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Protein Overview: ana-PA

General Information:
Name(s) found: ana-PA / FBpp0087642 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene anachronism is referred to in FlyBase by the symbol Dmel\ana (CG8084, FBgn0011746). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4956606..4965059. It has the cytological map location 45A1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: growth factor activity. It is reported to be involved in the biological process</span>: negative regulation of neuroblast proliferation. 15 alleles are reported. The phenotypes of these alleles are annotated with: neuroblast; thoracic neuroblast. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 474 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [NAS]
    Biological Process: negative regulation of neuroblast proliferation [NAS]
    growth [IEA]
    Molecular Function: growth factor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASAMRGEKC ERSRIRELVL ILSLITMAGD SRATPFDPSF FIEGVQSEVV NPFNRTILNR  60
   61 FNLTEEQILS IQNRSNPNMR DDSAQSSNQQ YLQQVATQRL NDIFKRVQKA ISNEPNGSAS 120
  121 KEKAGFPICN AETTNPEDWS LGNNVTLQFA SSVFISNNDD RLSSALLRLY KTNPGQTREH 180
  181 NPGQASTQPI STENPGNTAP NCAEQPPVGP QIRVTVSIVH QQRKKQRKKR TCNTAMLSSS 240
  241 STGWVEIDVK CALAYWEQQH RQQLRQQQPL QPQLTASVVG ILMIEVHDDE ENLLRPGLYF 300
  301 APPTCDQADI AVPWSVYRTE PFKSHLASWT LPRKPRLDIF FNGSNSMKNS YNTPKSRAFI 360
  361 ESTTSNSPTI DNQLDESGEY ESQQRVHAPL VHHRRHHHNH QQPESESESA QLEAEIEAEE 420
  421 LMSSASNSEQ QMEPISNHHR HRTGHHHPHH QLHQHHHHHH RHTKHHRIPA HKQE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..308] deduced N/A No confident structure predictions are available.
    2 View Details [309..474] FFAS03 1.04 Crystal Structure of Rv2632c


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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