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Protein Overview: l(2)44DEa-PA, l(...

General Information:
Name(s) found: l(2)44DEa-PH / FBpp0099849 [FlyBase]
l(2)44DEa-PE / FBpp0099846 [FlyBase]
l(2)44DEa-PB / FBpp0087780 [FlyBase]
l(2)44DEa-PA / FBpp0087779 [FlyBase]
Description(s) found:
Found 58 descriptions.
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  • The gene lethal (2) 44DEa is referred to in FlyBase by the symbol Dmel\l(2)44DEa (CG8732, FBgn0010609). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4553360..4570296. It has the cytological map location 44E1-44E2. Based on sequence similarity, it is predicted to have molecular function</span>: long-chain-fatty-acid-CoA ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 34 alleles are reported. No phenotypic data is available. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
  • The gene lethal (2) 44DEa is referred to in FlyBase by the symbol Dmel\l(2)44DEa (CG8732, FBgn0010609). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4553360..4570296. It has the cytological map location 44E1-44E2. Based on sequence similarity, it is predicted to have molecular function</span>: long-chain-fatty-acid-CoA ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 34 alleles are reported. No phenotypic data is available. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
  • The gene lethal (2) 44DEa is referred to in FlyBase by the symbol Dmel\l(2)44DEa (CG8732, FBgn0010609). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4553360..4570296. It has the cytological map location 44E1-44E2. Based on sequence similarity, it is predicted to have molecular function</span>: long-chain-fatty-acid-CoA ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 34 alleles are reported. No phenotypic data is available. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
  • The gene lethal (2) 44DEa is referred to in FlyBase by the symbol Dmel\l(2)44DEa (CG8732, FBgn0010609). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4553360..4570296. It has the cytological map location 44E1-44E2. Based on sequence similarity, it is predicted to have molecular function</span>: long-chain-fatty-acid-CoA ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 34 alleles are reported. No phenotypic data is available. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 715 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    Biological Process: metabolic process [IEA]
    Molecular Function: long-chain fatty acid-CoA ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFIEDDAQMD SFWVQSAIGA IKAIAFVYDI ITLPVYLVLQ KPWKRRQDSR RVKAKIVRND  60
   61 DNELTYRTTD PPRDVHVKML QENIDTLEKV FNYVAKTYTS KRCLGTRQIL SEEDEVQQNG 120
  121 RVFKKYNLGD YKWKTFTEAE RTAANFGRGL RELGQKPREN IVIFAETRAE WMIAAHGCFK 180
  181 QAMPIVTVYA TLGDDGVAHC ITETEVTTVI TSHDLLPKFK TLLDKCPLVK TIIYIEDQLQ 240
  241 KTETTGFKEG VKILPFNQVV KTGQDSKFEH VPPKGDDIAI IMYTSGSTGT PKGVLLSHKN 300
  301 CIATMKGFVD MVPIYPDDVL IGFLPLAHVF ELVAESVCLM TGVPIGYSTP LTLIDTSSKI 360
  361 KRGCKGDATV LKPTCMTSVP LILDRISKGI NDKVNSGSAF KKSLFKFLYQ YKVKWVQRGY 420
  421 KTPLIDKLVF KKVAKLMGGK VRIIMSGGAP LSADTHEQIK TCLCLELIQG YGLTETTSGA 480
  481 TVMDYRDMTY GRTGGPLTVC DIRLVNWEEG NYRVTNKPYP QGEVLIGGEC VSQGYYKLPG 540
  541 KTNEDFFEED GQRWFKTGDI GEIQADGVLK IIDRKKDLVK LQAGEYVSLG KVESELKTCG 600
  601 IIENICVYGD PTKQYTVALV VPNQNHLEEL AQKHGLGDKS FEELCSSPII EKAILKEIAE 660
  661 HARKCKLQKY EVPAAITLCK EVWSPDMGLV TAAFKLKRKD IQDRYQHDIN RMYAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..715] PSI-BLAST 137.0 No description for 2p2bA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.48

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle