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Protein Overview: FBpp0302051, Vps...

General Information:
Name(s) found: FBpp0302051 [FlyBase]
Vps28-PA / FBpp0087901 [FlyBase]
Description(s) found:
Found 30 descriptions.
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  • type=protein; loc=2R:complement(3966823..3967455); ID=FBpp0302051; name=Vps28-PB; parent=FBgn0021814,FBtr0310370; dbxref=FlyBase:FBpp0302051,FlyBase_Annotation_IDs:CG12770-PB,REFSEQ:NP_001260796,GB_protein:AGB93329; MD5=7cb4254324d20286de3b4636551eaf0a; length=210; release=r5.56; species=Dmel; [FlyBase]
  • The gene Vacuolar protein sorting 28 is referred to in FlyBase by the symbol Dmel\Vps28 (CG12770, FBgn0021814). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3966742..3967561. It has the cytological map location 44A4. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: regulation of multivesicular body size involved in endosome transport; actin cytoskeleton organization; compound eye development; embryonic development ending in birth or egg hatching; negative regulation of growth or development of symbiont in host; sperm individualization. 9 alleles are reported. The phenotypes of these alleles are annotated with: larval digestive system; spermatid; spermatozoon. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 210 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: sperm individualization [IMP]
    embryonic development ending in birth or egg hatching [IMP]
    regulation of multivesicular body size involved in endosome transport [IDA]
    compound eye development [IMP]
    actin cytoskeleton organization [IMP]
    Molecular Function: protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQEQSPELYE EVKLFRNARE REKYDNMADL YAIINTIQQL EKAYIRDCIT PQEYTAACSK  60
   61 YLVQYKVAFK QVQCDEFPSV ETFVKKFRLD CPAALERIRE DRPITIRDDK GNTSKCIAEI 120
  121 VSLFITIMDK LRLQINTMDA LQPDVKDLAD NMNRLSLIPE DFDAKLKVEK WLGSLNEMQA 180
  181 SDELSEGQVR QFLFDLESAY ADFNKLLHSQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..111] PSI-BLAST 31.154902 No description for 2cazB was found.
    2 View Details [112..210] PSI-BLAST 44.69897 No description for 2j9wA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.84486828479515 bayes_pls_golite062009
  • protein binding
    		•  1.057045320917 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle