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Protein Overview: Act42A-PA

General Information:
Name(s) found: Act42A-PA / FBpp0085365 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene Actin 42A is referred to in FlyBase by the symbol Dmel\Act42A (CG12051, FBgn0000043). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:1901415..1903190. It has the cytological map location 42A7. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of cytoskeleton. There is experimental evidence that it is involved in the biological process</span>: cytokinesis; phagocytosis, engulfment. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 376 amino acids

    Gene Ontology:
    Cellular Component: actin filament [ISS][NAS]
    Biological Process: phagocytosis, engulfment [IMP]
    cytoskeleton organization [ISS]
    cytokinesis [IMP]
    Molecular Function: ATP binding [IEA]
    protein binding [IEA]
    structural constituent of cytoskeleton [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCDEEVAALV VDNGSGMCKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDSYVGDEAQ  60
   61 SKRGILTLKY PIEHGIVTNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANREKM 120
  121 TQIMFETFNT PAMYVAIQAV LSLYASGRTT GIVLDSGDGV SHTVPIYEGY ALPHAILRLD 180
  181 LAGRDLTDYL MKILTERGYS FTTTAEREIV RDIKEKLCYV ALDFEQEMAT AASSSSLEKS 240
  241 YELPDGQVIT IGNERFRCPE SLFQPSFLGM EACGIHETTY NSIMKCDVDI RKDLYANTVL 300
  301 SGGTTMYPGI ADRMQKEITA LAPSTMKIKI VAPPERKYSV WIGGSILASL STFQQMWISK 360
  361 QEYDESGPSI VHRKCF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..376] PSI-BLAST 151.0 Actin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle