Protein Overview: sec71-PB

General Information:
Name(s) found:	sec71-PB / FBpp0080115 [FlyBase]
Description(s) found: Found 13 descriptions. SHOW ALL	The gene sec71 is referred to in FlyBase by the symbol Dmel\sec71 (CG7578, FBgn0028538). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:13793547..13799681. It has the cytological map location 34D1. Based on sequence similarity, it is predicted to have molecular function</span>: ARF guanyl-nucleotide exchange factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: ER to Golgi vesicle-mediated transport; intra-Golgi vesicle-mediated transport. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1614 amino acids
Gene Ontology:
Cellular Component:	Golgi apparatus [ISS]
Biological Process:	ER to Golgi vesicle-mediated transport [ISS] intra-Golgi vesicle-mediated transport [ISS] regulation of ARF protein signal transduction [IEA]
Molecular Function:	ARF guanyl-nucleotide exchange factor activity [ISS] binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHNNSTKTKE MFIVRALEKI LADKDIRRSH HSQLKKSCDS ALEQIKAELI SAGQIAEGNE  60
   61 LPCAALPLPK NDAASIINAE TYFLPFELAC KSRSPRIVVT ALDCLQKLIA YGHLTGSIQD 120
  121 SANPGHLLID RIVVTIYGCF SGPQTDEAVQ LQIIKALLTV VTSQHVEIHE FTLLQAVRTC 180
  181 YDIYLSSKNL VNQTTARATL TQMLNVIFAR MENQVYELPP PNSNPTNGSI HSEDCNGSGE 240
  241 ESLRDSDEVI ASELLAEIIS AAYNEAMKDQ ESVGEPEPTL NGNDYSSHSD HDSVELHSEN 300
  301 DAVVTAKFTH ILQKDAFLVF RALCKLSMKP LPDGHPDPKS HELRSKVLSL HLLLLILQNA 360
  361 GPVFRSNEMF IMAIKQYLCV ALSNNGVSLV PEVFELSLSI FVALLSNFKV HLKRQIEVFF 420
  421 KEIFLNILEA NSSSFEHKWM VIQALTRICA DAQSVVDIYV NYDCDFSAAN LFERLVNDLS 480
  481 KIAQGRQALE LGANPMQEKS MRIRGLECLV SILKCMVEWS KDLYVNPNMP VPPMQVQSPT 540
  541 STEQDQADTT IQTMHSGSSH SLNSNQEQLQ DLPEALEERK MRKEVMETGI ELFNRKPQKG 600
  601 VQFLQEKQLL GATCGDIARW LHEDERLDKT VIGNYIGEND DHSKEVMCAY IDAFDFRQME 660
  661 VVAALRFLLE GFRLPGEAQK IDRLMEKFAS RYCECNPKNQ LFQSADTVYV LAFSIIMLTT 720
  721 DLHSPQVKHK MTKEQYIKMN RGISDSKSDL PEEYLSSIYD EISEHEIKMK NNSGMLQQAK 780
  781 PTGKQAFITE KRRKLLWNME MEVISLTATN LMQSVSHVKS PFTSAKHLEH VRPMFKMAWT 840
  841 PFLAAFSVGL QDCDDPEIAT LCLDGIRCAI RIACIFHMSL ERDAYVQALA RFTLLNANSP 900
  901 INEMKAKNID TIKTLIMVAH TDGNYLGSSW LDIVKCISQL ELAQLIGTGV RPQFLSGAQT 960
  961 TLKDSLNPSV KEHIGETSSQ SVVVAVDRIF TGSMRLDGDA IVDFVKALCQ VSVDELQQQQ1020
 1021 PRMFSLQKIV EISYYNMERI RLQWSRIWQV LGEHFNAVGC NSNEEISFFA LDSLRQLSMK1080
 1081 FMEKGEFSNF RFQKDFLRPF EHIMKKNASP AIRDMVVRCI AQMVNSQAHN IRSGWKNIFS1140
 1141 IFHLAAGDNE EPIVELAFQT TGKIIGDLYK RQFAIMVDSF QDAVKCLSEF ATARFPDTSM1200
 1201 EAIRLVRTCA QCVHEAPQLF AEHAGMENDA SVAEEDRVWV RGWFPMLFSL SCVVNRCKLD1260
 1261 VRTRALTVLF EIVKTYGESF KPHWWKDLFN VIFRIFDNMK LPEHVTEKSE WMTTTCNHAL1320
 1321 YAIIDVFTQY FDVLGHLLLE ELFAQLHWCV QQSNEQLARS GTNCLENLVI SNGFKFNEST1380
 1381 WDKTCQCILD IFNATLPQDL LSWRPKAHSS NNIPQEHNHF EALHIRCVVQ LELIQTMDNI1440
 1441 VFFPATSRKE DAETLAQAAA DLTGGRSGSQ SQLLECQREE QGMYGYLRTR QLLTLADCLM1500
 1501 QSHRFAKRFN ADHDQRSLLW RAGFKGSVKP NLLKQETSSL ACVLRIFFKM YGDENRRSDW1560
 1561 PGIEQELVQF ATHVSNYYSL LCEMMCFDLK PELRSVLRRV FMRIGPVFNI MSVK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: sec71-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: