Protein Overview: Mt2-PA

General Information:
Name(s) found:	Mt2-PA / FBpp0079911 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7297918\|gb\|AAF53163.1\| methyltransferase 2, isoform A [Drosophila melanogaster] [NCBI NR] gi\|17137742\|ref\|NP_477475.1\| methyltransferase 2, isoform A [Drosophila melanogaster] [NCBI NR] The gene Methyltransferase 2 is referred to in FlyBase by the symbol Dmel\Mt2 (CG10692, FBgn0028707). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12096586..12097694. It has the cytological map location 33C4. There is experimental evidence that it has the molecular function</span>: DNA (cytosine-5-)-methyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: gene silencing; determination of adult lifespan; tRNA methylation; telomere maintenance; DNA methylation during embryonic development; DNA methylation. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG10692-PA translation from_gene[CG10692 Mt2 FBgn0028707] seq_release:3 mol_weight=39334 cds_boundaries:(2L:12,085,506..12,086,540[+]) aa_length:345 transcript_info:[CG10692-RA seq_release:3] gene_info:[gene symbol:Mt2 FBgn0028707 gene_boundaries:(2L: [hmr_yeast5_DM3-1_pombe.fasta] (Q9VKB3) Mt2 protein (EC 2.1.1.73) (Modification methylase) (Cytosine-specific methyltransferase) [DrosMelano7227.FASTAC.txt] (AE003635) Mt2 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG10692-PA, isoform A [Drosophila melanogaster]gi\|17137742\|ref\|NP_477475.1\| CG10692-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:12096635..12097672; ID=FBpp0079911; name=Mt2-PA; parent=FBgn0028707,FBtr0080329; dbxref=GB_protein:AAF53163.1,FlyBase:FBpp0079911,FlyBase_Annotation_IDs:CG10692-PA,REFSEQ:NP_477475,GB_protein:AAF53163; MD5=18a948e5966e3b6004f935c2eff9 [fly-100309-contam.fasta] DNA methyltransferase 2 CG10692-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] CG10692-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:12096635..12097672; ID=FBpp0079911; name=Mt2-PA; parent=FBgn0028707,FBtr0080329; dbxref=GB_protein:AAF53163.1,FlyBase:FBpp0079911,FlyBase_Annotation_IDs:CG10692-PA,REFSEQ:NP_477475,GB_protein:AAF53163; MD5=18a948e5966e3b6004f935c2eff98faf; length=345; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:12096635..12097672; ID=FBpp0079911; name=Mt2-PA; parent=FBgn0028707,FBtr0080329; dbxref=GB_protein:AAF53163.1,FlyBase:FBpp0079911,FlyBase_Annotation_IDs:CG10692-PA,REFSEQ:NP_477475,GB_protein:AAF53163; MD5=18a948e5966e3b6004f935c2eff98faf; length=345; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Methyltransferase 2, isoform A OS=Drosophila melanogaster GN=Mt2 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:12096635..12097672; ID=FBpp0079911; name=Mt2-PA; parent=FBgn0028707,FBtr0080329; dbxref=GB_protein:AAF53163.1,FlyBase:FBpp0079911,FlyBase_Annotation_IDs:CG10692-PA,REFSEQ:NP_477475,GB_protein:AAF53163,FlyMine:FBpp0079911,modMine:FBpp0079911; MD5=18a948e5966e3b6004f935c2eff98faf; length=345; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
Organism:	Drosophila melanogaster
Length:	345 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] nuclear chromatin [NAS]
Biological Process:	gene silencing [IMP] DNA methylation [IDA][ISS][NAS] determination of adult lifespan [IMP] DNA methylation involved in embryonic development [IMP] telomere maintenance [IMP] tRNA methylation [IMP]
Molecular Function:	DNA (cytosine-5-)-methyltransferase activity [IDA][ISS][NAS] DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLIVSSSIM IHAKLIYTFE DAQLDGQIVA ALDVNTVANA VYAHNYGSNL VKTRNIQSLS  60
   61 VKEVTKLQAN MLLMSPPCQP HTRQGLQRDT EDKRSDALTH LCGLIPECQE LEYILMENVK 120
  121 GFESSQARNQ FIESLERSGF HWREFILTPT QFNVPNTRYR YYCIARKGAD FPFAGGKIWE 180
  181 EMPGAIAQNQ GLSQIAEIVE ENVSPDFLVP DDVLTKRVLV MDIIHPAQSR SMCFTKGYTH 240
  241 YTEGTGSAYT PLSEDESHRI FELVKEIDTS NQDASKSEKI LQQRLDLLHQ VRLRYFTPRE 300
  301 VARLMSFPEN FEFPPETTNR QKYRLLGNSI NVKVVGELIK LLTIK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: Mt2-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: