Protein Overview: iHog-PA

General Information:
Name(s) found:	iHog-PA / FBpp0078993 [FlyBase]
Description(s) found: Found 21 descriptions. SHOW ALL	The gene interference Hedgehog is referred to in FlyBase by the symbol Dmel\iHog (CG9211, FBgn0031872). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:6945458..6948778. It has the cytological map location 27C6. There is experimental evidence that it has the molecular function</span>: heparin binding; protein binding; hedgehog receptor activity; protein homodimerization activity. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; cuticle pattern formation; positive regulation of smoothened signaling pathway; wing disc pattern formation. 16 alleles are reported. The phenotype of these alleles is annotated with: wing. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	886 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [ISS]
Biological Process:	wing disc pattern formation [IMP] positive regulation of smoothened signaling pathway [IMP] smoothened signaling pathway [IDA][IMP] cuticle pattern formation [IMP]
Molecular Function:	protein binding [IPI] protein homodimerization activity [IDA] hedgehog receptor activity [IPI] heparin binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLLTSSLLL FSLLTSRLEA IPVLEKSPAH PAHSAHPAHP AHPAHPAHPS PGVRILRAPE  60
   61 SLVAPLGDEV VLECETSLQP ERFEWSHRSS RSPGAGFKYL KTGTAKANVS QEAAISRLRV 120
  121 LVRPDTLGEY RCVGWFGPLV VTSTIARLEL ASTSLVDAQE SESPLQWRVS AGNSVLWSCG 180
  181 QQVQSNPSAS WSYYRNGVEI KPEFIGTNGN LFLSNVSSES SGSYSCQATN PASGERIQLP 240
  241 GSLQLQVTPE QRSESKSPHL LRGQPSSQEI TIREGSSLLL LCPGVGSPPP TVVWSSPDVV 300
  301 GAVKNKRSKV FGHALEISNT RVNDAGTYIC FQDNGVRPAL EHYIKVHVEQ PPQIVRPPWA 360
  361 DLTNEGDRLK LECKATGVPT PEIYWLLNGH SSIDDSEAEL SNNFLILHSV LKRHAGYVQC 420
  421 FARNRLGEHS AGTLLQVNPK QIQEPRESGG THRPKPNQGS RQKQMYPPTP PNVTRLSDES 480
  481 VMLRWMVPRN DGLPIVIFKV QYRMVGKRKN WQTTNDNIPY GKPKWNSELG KSFTASVTDL 540
  541 KPQHTYRFRI LAVYSNNDNK ESNTSAKFYL QPGAALDPMP VPELLEIEEY SETAVVLHWS 600
  601 LASDADEHLI TGYYAYYRPS SSAGEYFKAT IEGAHARSFK IAPLETATMY EFKLQSFSAA 660
  661 SASEFSALKQ GRTQRPKTST TEEPTLQMGD RDTTTPSHNE TFNMSPMLTG TIGGGAVLIL 720
  721 LLISTCFCVC RRRNSRSRGN NPNKPRMAEL RDDFVPLGNC SPTKQRQRTR HIHITLNPLA 780
  781 QQQQQALEEK NDTDQDAPYY QRPSSYDYDP TLRRMSSSSL RRSQRTLERA GGSNGSNNGN 840
  841 NNNLNQSAEA GSIENPGKPG RVLMKRPRLS SRSENLSSGS LNSVGV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: iHog-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: