Protein Overview: RhoGAP18B-PD

General Information:
Name(s) found:	RhoGAP18B-PD / FBpp0288899 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|95025511\|gb\|ABF50838.1\| RhoGAP18B-PD [Drosophila melanogaster] [NCBI NR] gi\|221499246\|ref\|NP_001138220.1\| RhoGAP18B, isoform D [Drosophila melanogaster] [NCBI NR] gi\|220901828\|gb\|ACL82950.1\| RhoGAP18B, isoform D [Drosophila melanogaster] [NCBI NR] The gene RhoGAP18B is referred to in FlyBase by the symbol Dmel\RhoGAP18B (CG42274, FBgn0261461). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19030259..19059362. It has the cytological map location 18A3-18A4. There is experimental evidence that it has the molecular function</span>: GTPase activator activity. There is experimental evidence that it is involved in the biological process</span>: behavioral response to nicotine; behavioral response to ethanol; actin filament organization. 65 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] type=protein; loc=X:complement(19037618..19037801,19038038..19038529,19038597..19038624,19040001..19040175,19044844..19045992,19047061..19047291); ID=FBpp0288899; name=RhoGAP18B-PD; parent=FBgn0259169,FBtr0299624; dbxref=FlyBase:FBpp0288899,FlyBase_Annota [fly-100309-contam.fasta] RhoGAP18B-PD [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=X:complement(19037618..19037801,19038038..19038529,19038597..19038624,19040001..19040175,19044844..19045992,19047061..19047291); ID=FBpp0288899; name=RhoGAP18B-PD; parent=FBgn0259169,FBtr0299624; dbxref=FlyBase:FBpp0288899,FlyBase_Annotation_IDs:CG42274-PD,REFSEQ:NP_001138220,GB_protein:ACL82950; MD5=c9488ca23a84b6c928e9ccc94432e858; length=752; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=X:complement(19037618..19037801,19038038..19038529,19038597..19038624,19040001..19040175,19044844..19045992,19047061..19047291); ID=FBpp0288899; name=RhoGAP18B-PD; parent=FBgn0259169,FBtr0299624; dbxref=FlyBase:FBpp0288899,FlyBase_Annotation_IDs:CG42274-PD,REFSEQ:NP_001138220,GB_protein:ACL82950; MD5=c9488ca23a84b6c928e9ccc94432e858; length=752; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] RhoGAP18B, isoform D OS=Drosophila melanogaster GN=RhoGAP18B PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=X:complement(19037618..19037801,19038038..19038529,19038597..19038624,19040001..19040175,19044844..19045992,19047061..19047291); ID=FBpp0288899; name=RhoGAP18B-PD; parent=FBgn0261461,FBtr0299624; dbxref=FlyBase:FBpp0288899,FlyBase_Annotation_IDs:CG42274-PD,REFSEQ:NP_001138220,GB_protein:ACL82950,FlyMine:FBpp0288899,modMine:FBpp0288899; MD5=c9488ca23a84b6c928e9ccc94432e858; length=752; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=X:complement(join(19153028..19153258,19150811..19151959,19145968..19146142,19144564..19144591,19144005..19144496,19143585..19143768)); ID=FBpp0288899; name=RhoGAP18B-PD; parent=FBgn0261461,FBtr0299624; dbxref=FlyBase:FBpp0288899,FlyBase_Annotation_IDs:CG42274-PD,REFSEQ:NP_001138220,GB_protein:ACL82950,FlyMine:FBpp0288899,modMine:FBpp0288899; MD5=c9488ca23a84b6c928e9ccc94432e858; length=752; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=X:complement(join(19153028..19153258,19150811..19151959,19145968..19146142,19144564..19144591,19144005..19144496,19143585..19143768)); ID=FBpp0288899; name=RhoGAP18B-PD; parent=FBgn0261461,FBtr0299624; dbxref=FlyBase:FBpp0288899,FlyBase_Annotation_IDs:CG42274-PD,REFSEQ:NP_001138220,GB_protein:ACL82950,FlyMine:FBpp0288899,modMine:FBpp0288899; MD5=c9488ca23a84b6c928e9ccc94432e858; length=752; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of Q9VWL7, Rho GTPase activating protein at 18B, isoform D OS=Drosophila melanogaster GN=RhoGAP18B PE=1 SV=1 [DROME.fasta.20160308] FBpp0288899 type=protein; loc=X:complement(join(19153028..19153258,19150811..19151959,19145968..19146142,19144564..19144591,19144005..19144496,19143585..19143768)); ID=FBpp0288899; name=RhoGAP18B-PD; parent=FBgn0261461,FBtr0299624; dbxref=FlyBase:FBpp0288899,FlyBase_Annotation_IDs:CG42274-PD,REFSEQ:NP_001138220,GB_protein:ACL82950,FlyMine:FBpp0288899,modMine:FBpp0288899; MD5=c9488ca23a84b6c928e9ccc94432e858; length=752; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=X:complement(join(19153028..19153258,19150811..19151959,19145968..19146142,19144564..19144591,19144005..19144496,19143585..19143768)); ID=FBpp0288899; name=RhoGAP18B-PD; parent=FBgn0261461,FBtr0299624; dbxref=FlyBase:FBpp0288899,FlyBase_Annotation_IDs:CG42274-PD,REFSEQ:NP_001138220,GB_protein:ACL82950,UniProt/TrEMBL:Q00IN0,FlyMine:FBpp0288899,modMine:FBpp0288899; MD5=c9488ca23a84b6c928e9ccc94432e858; length=752; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	752 amino acids
Gene Ontology:
Cellular Component:	intracellular [IEA]
Biological Process:	behavioral response to nicotine [IMP] signal transduction [IEA] actin filament organization [IMP] behavioral response to ethanol [IMP]
Molecular Function:	GTPase activator activity [IDA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAPKPNGEA ERPSTNSNNN TINCSSNNNN DNISNNNNNH HTVDNESGIN NNKNNDGNAN  60
   61 CNVNEQQQQQ QQQPITQNCV IKVRRPAPKV PVRNPNTSLS NPRQIEEEQT KPNGGKKDNL 120
  121 RGNSFAAENS SPEEQEEESI YQPIWQFKTI EPVDQEIIEA LPVEGEDEED EDEEDDDVDD 180
  181 EEEDLGDYDE SLPSDADPDV MALQAAAVFA AGVRHKLSTS TLTKRSKMMM PTPLPSPTAS 240
  241 MDHGAWETDM EFMYSRESKE EADETLSLGS TVTNSTATLG SISSTGSSVT GQPKDTPKDL 300
  301 PADQQPSVVV HPILRNICIF YSQKDPKKYS AIFYDYHLSL VHQRFMTRIR RPAPPPPAQL 360
  361 ATSNTTSLAP RSDDSGCSCE AEDSYNHQHN PTPAIPKPLK EEWERAVLAA GAVAGKRGVA 420
  421 PRTGRKLRVR SNARLLLTDS VLAWRETLQD VNCCEDEEDM IVPVTDILRA QQIQEDNEVQ 480
  481 QTQQSTILQR YKSVSIGNLL DLPGEDDKKS IKNRMRMKFA VNSNVFRINR SPKSEKKSRS 540
  541 RRGQVNSLYL DEQKYPLFAA PLSALELNMT DHPNVPRFVV DVCAYIEQPE CIEQDGLYRA 600
  601 SGNKVLVDEL RKKLTHVYDP RWLKTDDIHT LTSLHKQFFR ELTSPLITQE AYERLGRSLN 660
  661 DDAAIERMSL AFDDMPEPNR STLRFLIRHL TRVAAASASN RMPSTNLAIV WGPCLLSANQ 720
  721 IQLDIGRMNM LAKVLIENYD RIFHPDNERL VC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: RhoGAP18B-PD

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: