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Protein Overview: Tgt-PA

General Information:
Name(s) found: Tgt-PA / FBpp0077636 [FlyBase]
Description(s) found:
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  • gi|8928447|sp|Q9VPY8.1|TGT_DROME RecName: Full=Probable queuine tRNA-ribosyltransferase; AltName: Full=tRNA-guanine transglycosylase; AltName: Full=Guanine insertion enzyme [NCBI NR]
  • gi|7296102|gb|AAF51396.1| tRNA-guanine transglycosylase [Drosophila melanogaster] [NCBI NR]
  • gi|19920510|ref|NP_608585.1| tRNA-guanine transglycosylase [Drosophila melanogaster] [NCBI NR]
  • gi|15292377|gb|AAK93457.1| LP01967p [Drosophila melanogaster] [NCBI NR]
  • Probable queuine tRNA-ribosyltransferase OS=Drosophila melanogaster GN=Tgt PE=2 SV=1 [Swiss-Prot]
  • The gene tRNA-guanine transglycosylase is referred to in FlyBase by the symbol Dmel\Tgt (CG4947, FBgn0031321). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:1184088..1185698. It has the cytological map location 21F2. Based on sequence similarity, it is predicted to have molecular function</span>: queuine tRNA-ribosyltransferase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: queuosine biosynthetic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG4947-PA translation from_gene[CG4947 CG4947 FBgn0031321] seq_release:3 mol_weight=47751 cds_boundaries:(2L:1,185,832..1,187,180[+]) aa_length:427 transcript_info:[CG4947-RA seq_release:3] gene_info:[gene symbol:CG4947 FBgn0031321 gene_boundaries:(2L [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VPY8) Probable queuine tRNA-ribosyltransferase (EC 2.4.2.29) (tRNA-guanine transglycosylase) (Guanine insertion enzyme) [DrosMelano7227.FASTAC.txt]
  • (AE003587) CG4947 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG4947-PA [Drosophila melanogaster]gi|15292377|gb|AAK93457.1| LP01967p [Drosophila melanogaster]gi|19920510|ref|NP_608585.1| CG4947-PA [Drosophila melanogaster]gi|8928447|sp|Q9VPY8|TGT_DROME Probable queuine tRNA-ribosyltransferase (tRNA-guanine transg [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:join(1184166..1184254,1184323..1185517); ID=FBpp0077636; name=Tgt-PA; parent=FBgn0031321,FBtr0077971; dbxref=FlyBase:FBpp0077636,FlyBase_Annotation_IDs:CG4947-PA,GB_protein:AAF51396.1,REFSEQ:NP_608585,GB_protein:AAF51396; MD5=a9cd3317 [fly-100309-contam.fasta]
  • tRNA-guanine transglycosylase CG4947-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG4947-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Probable queuine tRNA-ribosyltransferase (tRNA-guanine transglycosylase) (Guanine insertion enzyme) [nr-271106-contam.fasta]
  • LP01967p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2L:join(1184166..1184254,1184323..1185517); ID=FBpp0077636; name=Tgt-PA; parent=FBgn0031321,FBtr0077971; dbxref=FlyBase:FBpp0077636,FlyBase_Annotation_IDs:CG4947-PA,GB_protein:AAF51396.1,REFSEQ:NP_608585,GB_protein:AAF51396; MD5=a9cd331795c6a8bbe5d888b2744b07df; length=427; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:join(1184166..1184254,1184323..1185517); ID=FBpp0077636; name=Tgt-PA; parent=FBgn0031321,FBtr0077971; dbxref=FlyBase:FBpp0077636,FlyBase_Annotation_IDs:CG4947-PA,GB_protein:AAF51396.1,REFSEQ:NP_608585,GB_protein:AAF51396; MD5=a9cd331795c6a8bbe5d888b2744b07df; length=427; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=2L:join(1184166..1184254,1184323..1185517); ID=FBpp0077636; name=Tgt-PA; parent=FBgn0031321,FBtr0077971; dbxref=FlyBase:FBpp0077636,FlyBase_Annotation_IDs:CG4947-PA,GB_protein:AAF51396.1,REFSEQ:NP_608585,GB_protein:AAF51396,FlyMine:FBpp0077636,modMine:FBpp0077636; MD5=a9cd331795c6a8bbe5d888b2744b07df; length=427; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:join(1184166..1184254,1184323..1185517); ID=FBpp0077636; name=Tgt-PA; parent=FBgn0031321,FBtr0077971; dbxref=FlyBase:FBpp0077636,FlyBase_Annotation_IDs:CG4947-PA,GB_protein:AAF51396.1,REFSEQ:NP_608585,GB_protein:AAF51396,FlyMine:FBpp0077636,modMine:FBpp0077636; MD5=a9cd331795c6a8bbe5d888b2744b07df; length=427; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:join(1184166..1184254,1184323..1185517); ID=FBpp0077636; name=Tgt-PA; parent=FBgn0031321,FBtr0077971; dbxref=FlyBase:FBpp0077636,FlyBase_Annotation_IDs:CG4947-PA,GB_protein:AAF51396.1,REFSEQ:NP_608585,GB_protein:AAF51396,FlyMine:FBpp0077636,modMine:FBpp0077636; MD5=a9cd331795c6a8bbe5d888b2744b07df; length=427; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0077636 type=protein; loc=2L:join(1184166..1184254,1184323..1185517); ID=FBpp0077636; name=Tgt-PA; parent=FBgn0031321,FBtr0077971; dbxref=FlyBase:FBpp0077636,FlyBase_Annotation_IDs:CG4947-PA,GB_protein:AAF51396.1,REFSEQ:NP_608585,GB_protein:AAF51396,FlyMine:FBpp0077636,modMine:FBpp0077636; MD5=a9cd331795c6a8bbe5d888b2744b07df; length=427; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:join(1184166..1184254,1184323..1185517); ID=FBpp0077636; name=Tgt-PA; parent=FBgn0031321,FBtr0077971; dbxref=FlyBase:FBpp0077636,FlyBase_Annotation_IDs:CG4947-PA,GB_protein:AAF51396.1,REFSEQ:NP_608585,GB_protein:AAF51396,UniProt/Swiss-Prot:Q9VPY8,FlyMine:FBpp0077636,modMine:FBpp0077636; MD5=a9cd331795c6a8bbe5d888b2744b07df; length=427; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 427 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: queuosine biosynthetic process [ISS]
    Molecular Function: queuine tRNA-ribosyltransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPSHIPPLT YKVVAECSVS KARAGLMTLR HSEVNTPVFM PVGTQGTLKG IVPDQLIELN  60
   61 CQILLGNTYH LGLRPGIETL KKAGGLHKFM GWPRAILTDS GGFQMVSLLQ LAEIDEHGVN 120
  121 FRSPFDNSQC MLTPEHSIEI QNAIGGDIMM QLDDVVKTTT TGPRVEEAME RTIRWVDRCI 180
  181 EAHARDDDQS LFPIVQGGLD VPLRQRCVSA LMERQVRGFA VGGLSGGESK HDFWRMVDVC 240
  241 TGYLPKDKPR YLMGVGFAAD LVVCVALGID MFDCVFPTRT ARFGCALVDS GQLNLKQPKY 300
  301 KLDMEPIDKD CDCSTCRRYT RSYLHHIATN ESVSSSLLSI HNVAYQLRLM RSMREAIQRD 360
  361 EFPQFVADFM ARHFKAEPVP AWIREALSAV NIQLPADPER IDEQDQKPKT EKRRETEDVA 420
  421 EEQVASS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle