Protein Overview: FGFR1_RAT

General Information:
Name(s) found:	FGFR1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|544292\|sp\|Q04589.1\|FGFR1_RAT RecName: Full=Basic fibroblast growth factor receptor 1; Short=FGFR-1; Short=bFGF-R; AltName: Full=MFR; AltName: CD_antigen=CD331; Flags: Precursor [NCBI NR] gi\|444772\|prf\|\|1908208A fibroblast growth factor receptor 1 [NCBI NR] pir\|\|S29840 fibroblast growth factor receptor 1 - rat [NCBI NR] gi\|220738\|dbj\|BAA02059.1\| FGF receptor-1 [Rattus norvegicus] [NCBI NR] gi\|13162333\|ref\|NP_077060.1\| fibroblast growth factor receptor 1 [Rattus norvegicus] [NCBI NR] (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC 2.7.1.112) (FGFR-1) (bFGF-R) (MFR) [Swiss-Prot] Fibroblast growth factor receptor 1 OS=Rattus norvegicus GN=Fgfr1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):16-66967176 Basic fibroblast growth factor receptor 1 precursor [hmr_yeast5_DM3-1_pombe.fasta] FGF receptor-1 [HMR_022704-rand.fasta] FGF receptor-1 [Rattus norvegicus]gi\|544292\|sp\|Q04589\|FGR1_RAT Basic fibroblast growth factor receptor 1 precursor (FGFR-1) (bFGF-R) (MFR)gi\|346998\|pir\|\|S29840 fibroblast growth factor receptor 1 - ratgi\|220738\|dbj\|BAA02059.1\| FGF receptor-1 [Rattus no [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Basic fibroblast growth factor receptor 1 precursor [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_024146) FGF receptor-1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Basic fibroblast growth factor receptor 1 precursor (FGFR-1) (bFGF-R) (MFR) (CD331 antigen) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] FGF receptor-1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] fibroblast growth factor receptor 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] fibroblast growth factor receptor 1 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Fgfr1 Basic fibroblast growth factor receptor 1 [rat-ipi-250309-contam.fasta] Basic fibroblast growth factor receptor 1 OS=Rattus norvegicus GN=Fgfr1 [011711_HMR.fasta] Basic fibroblast growth factor receptor 1 OS=Rattus norvegicus GN=Fgfr1 PE=1 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	822 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA] plasma membrane [UNKNOWN]
Biological Process:	lung-associated mesenchyme development [UNKNOWN] positive regulation of cardiac muscle cell proliferation [UNKNOWN][IEA] positive regulation of cell proliferation [UNKNOWN][IEA] chondrocyte differentiation [UNKNOWN][IEA] paraxial mesoderm development [UNKNOWN] fibroblast growth factor receptor signaling pathway [UNKNOWN][IEA] blood vessel morphogenesis [UNKNOWN] generation of neurons [UNKNOWN][IEA] protein amino acid phosphorylation [IEA] branching involved in salivary gland morphogenesis [UNKNOWN][IEA] regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [UNKNOWN][IEA] salivary gland morphogenesis [UNKNOWN] embryonic limb morphogenesis [UNKNOWN][IEA] positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [UNKNOWN][IEA] midbrain development [UNKNOWN][IEA] angiogenesis [UNKNOWN][IEA] in utero embryonic development [UNKNOWN][IEA] mesenchymal cell differentiation [UNKNOWN][IEA] lung development [UNKNOWN][IEA] neuron projection development [IDA] positive regulation of mesenchymal cell proliferation [UNKNOWN][IEA] cell maturation [UNKNOWN][IEA] brain development [UNKNOWN] regulation of cell proliferation [UNKNOWN][IDA] ureteric bud development [UNKNOWN][IEA] regulation of lateral mesodermal cell fate specification [UNKNOWN] negative regulation of apoptosis [UNKNOWN][IEA] inner ear morphogenesis [UNKNOWN][IEA] induction of an organ [UNKNOWN][IEA] regulation of gene expression [UNKNOWN][IEA]
Molecular Function:	nucleotide binding [IEA] fibroblast growth factor receptor activity [UNKNOWN][IEA][TAS] ATP binding [IEA] protein tyrosine kinase activity [UNKNOWN][IEA] protein binding [UNKNOWN][IEA][IPI] heparin binding [IEA] fibroblast growth factor binding [IEA] receptor activity [IEA] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWGWRGLLFW AVLVTATLCT ARPAPTLPEQ AQPWGVPVEV ESLLVHPGDL LQLRCRLRDD  60
   61 VQSINWLRDG VQLAESNRTR ITGEEVEVRD SIPADSGLYA CVTNSPSGSD TTYFSVNVSD 120
  121 ALPSSEDDDD DDDSSSEEKE TDNTKPNRRP VAPYWTSPEK MEKKLHAVPA AKTVKFKCPS 180
  181 SGTPSPTLRW LKNGKEFKPD HRIGGYKVRY ATWSIIMDSV VPSDKGNYTC IVENEYGSIN 240
  241 HTYQLDVVER SPHRPILQAG LPANKTVALG SNVEFMCKVY SDPQPHIQWL KHIEVNGSKI 300
  301 GPDNLPYDQI LKTAGVNTTD KEMEVLHLRN VSFEDAGEYT CLAGNSIGLS HHSAWLTVLE 360
  361 ALEERPAVMT SPLYLEIIIY CTGAFLISCM VGSVIIYKMK SGTKKSDFHS QMAVHKLAKS 420
  421 IPLRRQVTVS ADSSASMNSG VLLVRPSRLS SSGTPMLAGV SEYELPEDPR WELPRDRLVL 480
  481 GKPLGEGCFG QVVLAEAIGL DKDKPNRVTK VAVKMLKSDA TEKDLSDLIS EMEMMKMIGK 540
  541 HKNIINLLGA CTQDGPLYVI VEYASKGNLR EYLQARRPPG LEYCYNPSHN PEEQLSSKDL 600
  601 VSCAYQVARG MEYLASKKCI HRDLAARNVL VTEDNVMKIA DFGLARDIHH IDYYKKTTNG 660
  661 RLPVKWMAPE ALFDRIYTHQ SDVWSFGVLL WEIFTLGGSP NPGVPVEELF KLLKEGHRMD 720
  721 KPSNCTNELY MMMRDCWNAV PSQRPTFKQL VEDLDRIVAL TSNQEYLDLS MPLDQDSPSF 780
  781 PDTRSSTCSS GEDSVFSHEP FPEEPCLPRH PTQLANGGLN RR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: FGFR1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: