General Information: |
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Name(s) found: |
IL6RB_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 918 amino acids |
Gene Ontology: |
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Cellular Component: |
extracellular space
[UNKNOWN]
oncostatin-M receptor complex [UNKNOWN][IEA] membrane [IEA] ciliary neurotrophic factor receptor complex [UNKNOWN][IEA] external side of plasma membrane [UNKNOWN][IEA] integral to membrane [IEA] cellular_component [ND] interleukin-6 receptor complex [UNKNOWN][IEA] |
Biological Process: |
response to cytokine stimulus
[UNKNOWN][IEA]
positive regulation of tyrosine phosphorylation of Stat3 protein [UNKNOWN][IEA] signal transduction [UNKNOWN][IEA] regulation of Notch signaling pathway [UNKNOWN][IEA] positive regulation of cell proliferation [UNKNOWN][IEA] reduction of cytosolic calcium ion concentration [IMP] response to nutrient [IEP] positive regulation of astrocyte differentiation [UNKNOWN] positive regulation of T cell proliferation [UNKNOWN][IEA] positive regulation of osteoblast differentiation [UNKNOWN][IEA] positive regulation of tyrosine phosphorylation of Stat1 protein [UNKNOWN][IEA] triglyceride mobilization [IMP] JAK-STAT cascade [IMP] positive regulation of cell growth [TAS] glycogen metabolic process [UNKNOWN][IEA] regulation of hormone secretion [TAS] cytokine-mediated signaling pathway [UNKNOWN] leukemia inhibitory factor signaling pathway [UNKNOWN][IEA] ciliary neurotrophic factor-mediated signaling pathway [UNKNOWN][IEA] negative regulation of interleukin-6-mediated signaling pathway [UNKNOWN] positive regulation of smooth muscle cell migration [IMP] interleukin-27-mediated signaling pathway [UNKNOWN][IEA] |
Molecular Function: |
growth factor binding
[UNKNOWN]
receptor activity [IEA] cytokine activity [TAS] cytokine receptor activity [IEA] ciliary neurotrophic factor receptor binding [UNKNOWN][IEA] interleukin-6 receptor binding [UNKNOWN][IEA] ciliary neurotrophic factor receptor activity [UNKNOWN] interleukin-11 receptor activity [UNKNOWN][IEA] protein binding [UNKNOWN] oncostatin-M receptor activity [UNKNOWN][IEA] leukemia inhibitory factor receptor activity [UNKNOWN][IEA] interleukin-6 receptor activity [UNKNOWN][IEA] interleukin-11 binding [UNKNOWN] interleukin-6 binding [UNKNOWN] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MSALRIWLMQ ALLIFLTTES IGQLVEPCGY IYPEFPVVQR GSNFTATCVL KEKCLQVYSV 60 61 NATYIVWKTN HVAVPKEQVT VINRTASSVT FTDVVFQNVQ LTCNILSFGQ IEQNVYGITI 120 121 LSGYPPDIPT NLSCIVNEGK NMLCQLDPGR ETYLETNYTL KSEWATEKFP DCRTKHGTSS 180 181 CMMGYTPIYF VNIEVWVEAE NALGNVSSEP INFDPVDKVK PSPPHNLSVT NSEELSSILK 240 241 LAWVNSGLDS ILRLKSDIQY RTKDASTWIQ VPLEDTVSPR TSFTVQDLKP FTEYVFRIRS 300 301 IKENGKGYWS DWSEEASGTT YEDRPSKAPS FWYKVNANHP QEYRSARLIW KTLPLSEANG 360 361 KILDYEVVLT QSKSVSQTYT VNGTELIVNL TNNRYVASLA ARNVVGKSPA TVLTIPGSHF 420 421 KASHPVVDLK AFPKDNLLWV EWTPPSKPVN KYILEWCVLS ENSPCIPDWQ QEDGTVNRTH 480 481 LRGSLLESKC YLITVTPVFP GGPGSPESMK AYLKQAAPSK GPTVRTKKVG KNEAVLEWDH 540 541 LPVDVQNGFI RNYSISYRTS VGKEMVVRVD SSHTEYTLSS LSSDTLYMVH MAAYTEEGGK 600 601 DGPEFTFTTL KFAQGEIEAI VVPVCLAFLL TTLLGVLFCF NKRDLIKKHI WPNVPDPSKS 660 661 HIAQWSPHTP PRHNFNSKDQ MYSDANFTDV SVVEIEANNK KPCPDDLKSL DLFKKEKIST 720 721 EGHSSGIGGS SCMSSSRPSI SSSEENESAQ STASTVQYST VVHSGYRHQV PSVQVFSRSE 780 781 STQPLLDSEE RPEDLQLVDS VDSGDEILPR QQYFKQSCSQ PGASPDVSHF GRSSQVPSGS 840 841 EEDFVRLKQQ QVSDHISEPY GSEQRRLFQE GSVADALGTG TDGQIERFES VGMETAMDED 900 901 ISKSYLPQTV RQGGYMPQ |
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