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Protein Overview: PK3C3_RAT

General Information:
Name(s) found: PK3C3_RAT [Swiss-Prot]
Description(s) found:
Found 20 descriptions.
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  • Phosphatidylinositol 3-kinase catalytic subunit type 3 OS=Rattus norvegicus GN=Pik3c3 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 887 amino acids

    Gene Ontology:
    Cellular Component: phosphoinositide 3-kinase complex [IEA]
    cytosol [UNKNOWN]
    cellular_component [ND]
    Biological Process: autophagic vacuole assembly [IMP]
    endosome organization [IMP]
    regulation of protein secretion [IMP]
    phosphoinositide-mediated signaling [IDA][IEA]
    phosphoinositide phosphorylation [IEA]
    response to leucine [IEP]
    protein maturation by peptide bond cleavage [IMP]
    protein amino acid phosphorylation [UNKNOWN][IEA]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    protein binding [UNKNOWN][IPI]
    inositol or phosphatidylinositol kinase activity [IEA]
    protein kinase activity [UNKNOWN][IEA]
    binding [IEA]
    transferase activity [IEA]
    phosphotransferase activity, alcohol group as acceptor [IEA]
    phosphoinositide 3-kinase activity [IMP]
    1-phosphatidylinositol-3-kinase activity [IDA][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEAEKFHYI YSCDLDINVQ LKIGSLEGKR EQKSYKAVLE DPMLKFSGLY QETCSDLYVT  60
   61 CQVFAEGKPL ALPVRTSYKP FSTRWNWNEW LKLPVKYPDL PRNAQVALTI WDVYGPGRAV 120
  121 PVGGTTVSLF GKYGMFRQGM HDLKVWPNVE ADGSEPTRTP GRTSSTLSED QMSRLAKLTK 180
  181 AHRQGHMVKV DWLDRLTFRE IEMINESEKR SSNFMYLMVE FRCVKCDDKE YGIVYYEKDG 240
  241 DESSPILTSF ELVKVPDPQM SMENLVESKH HKLARSLRSG PSDHDLKPNA TTRDQLNIIV 300
  301 SYPPTKQLTY EEQDLVWKFR YYLTNQEKAL TKFLKCVNWD LPQEAKQALE LLGKWKPMDV 360
  361 EDSLELLSSH YTNPTVRRYA VARLRQADDE DLLMYLLQLV QALKYENFDD IKNGLEPTKK 420
  421 DSQASVSESL SSSGVSSADI DSSQIITNPL PPVASPPPAS KSKEVSDGEN LEQDLCTFLI 480
  481 SRACKNSTLA NYLYWYVIVE CEDQDTQQRD PKTHEMYLNV MRRFSQALLK GDKSVRVMRS 540
  541 LLAAQQTFVD RLVHLMKAVQ RESGNRKKKN ERLQALLGDN EKMNLSDVEL IPLPLEPQVK 600
  601 IRGIIPETAT LFKSALMPAQ LFFKTEDGGK YPVIFKHGDD LRQDQLILQI ISLMDKLLRK 660
  661 ENLDLKLTPY KVLATSTKHG FMQFIQSVPV AEVLDTEGSI QNFFRKYAPS ETGPNGISAE 720
  721 VMDTYVKSCA GYCVITYILG VGDRHLDNLL LTKTGKLFHI DFGYILGRDP KPLPPPMKLN 780
  781 KEMVEGMGGT QSEQYQEFRK QCYTAFLHLR RYSNLILNLF SLMVDANIPD IALEPDKTVK 840
  841 KVQDKFRLDL SDEEAVHYMQ SLIDESVHAL FAAVVEQIHK FAQYWRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle