Protein Overview: GBRB2_RAT

General Information:
Name(s) found:	GBRB2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|S04465 gamma-aminobutyric acid/benzodiazepine receptor beta-2 chain precursor - rat [NCBI NR] gi\|6978869\|ref\|NP_037089.1\| gamma-aminobutyric acid receptor, subunit beta 2 [Rattus norvegicus] [NCBI NR] gi\|52000957\|sp\|P63138.1\|GBRB2_RAT RecName: Full=Gamma-aminobutyric acid receptor subunit beta-2; AltName: Full=GABA(A) receptor subunit beta-2; Flags: Precursor [NCBI NR] gi\|46371157\|gb\|AAS90347.1\| GABA-A receptor beta2 subunit [Rattus norvegicus] [NCBI NR] gi\|149052307\|gb\|EDM04124.1\| gamma-aminobutyric acid (GABA-A) receptor, subunit beta 2 [Rattus norvegicus] [NCBI NR] Gamma-aminobutyric acid receptor subunit beta-2 OS=Rattus norvegicus GN=Gabrb2 PE=1 SV=1 [Swiss-Prot] (P63138) Gamma-aminobutyric-acid receptor beta-2 subunit precursor (GABA(A) receptor) [Swiss-Prot] Ensembl_locations(Chr-bp):10-25657979 Gamma-aminobutyric-acid receptor beta-2 subunit precursor [hmr_yeast5_DM3-1_pombe.fasta] gamma-aminobutyric acid receptor, subunit beta 2; Gamma-aminobutyric acid receptor beta 2 [HMR_022704-rand.fasta] gamma-aminobutyric acid receptor, subunit beta 2 [Rattus norvegicus]gi\|6679909\|ref\|NP_032096.1\| gamma-aminobutyric acid (GABA-A) receptor, subunit beta 2 [Mus musculus]gi\|57798\|emb\|CAA33494.1\| GABA(A) receptor beta-2 preprotein [Rattus sp.]gi\|46371157\| [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Gamma-aminobutyric-acid receptor beta-2 subunit precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012957) gamma-aminobutyric acid receptor beta 2 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] gamma-aminobutyric acid receptor, subunit beta 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Gamma-aminobutyric acid receptor subunit beta-2 precursor (GABA(A) receptor subunit beta-2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] gamma-aminobutyric acid (GABA-A) receptor, subunit beta 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] GABA-A receptor beta2 subunit [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 GAMMA-AMINOBUTYRIC-ACID RECEPTOR BETA-2 SUBUNIT PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Gamma-aminobutyric-acid receptor subunit beta-2 precursor (GABA(A) receptor subunit beta-2) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 [rat-ipi-250309-contam.fasta] Gamma-aminobutyric acid receptor subunit beta-2 OS=Rattus norvegicus GN=Gabrb2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	474 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] chloride channel complex [IEA] postsynaptic membrane [IEA] integral to membrane [IEA] cytosol [IDA] cell junction [IEA] synapse [IEA] plasma membrane [IEA]
Biological Process:	ion transport [IEA] gamma-aminobutyric acid signaling pathway [TAS]
Molecular Function:	ion channel activity [IEA] protein binding [UNKNOWN][IPI] GABA-A receptor activity [IMP][TAS] chloride channel activity [IEA] inhibitory extracellular ligand-gated ion channel activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWRVRKRGYF GIWSFPLIIA AVCAQSVNDP SNMSLVKETV DRLLKGYDIR LRPDFGGPPV  60
   61 AVGMNIDIAS IDMVSEVNMD YTLTMYFQQA WRDKRLSYNV IPLNLTLDNR VADQLWVPDT 120
  121 YFLNDKKSFV HGVTVKNRMI RLHPDGTVLY GLRITTTAAC MMDLRRYPLD EQNCTLEIES 180
  181 YGYTTDDIEF YWRGDDNAVT GVTKIELPQF SIVDYKLITK KVVFSTGSYP RLSLSFKLKR 240
  241 NIGYFILQTY MPSILITILS WVSFWINYDA SAARVALGIT TVLTMTTINT HLRETLPKIP 300
  301 YVKAIDMYLM GCFVFVFMAL LEYALVNYIF FGRGPQRQKK AAEKAANANN EKMRLDVNKM 360
  361 DPHENILLST LEIKNEMATS EAVMGLGDPR STMLAYDASS IQYRKAGLPR HSFGRNALER 420
  421 HVAQKKSRLR RRASQLKITI PDLTDVNAID RWSRIFFPVV FSFFNIVYWL YYVN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: GBRB2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: