Protein Overview: MAGI2_RAT

General Information:
Name(s) found:	MAGI2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|7514091\|pir\|\|T14152 synaptic scaffolding protein S-SCAM - rat [NCBI NR] gi\|37537749\|sp\|O88382.1\|MAGI2_RAT RecName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2; AltName: Full=Membrane-associated guanylate kinase inverted 2; Short=MAGI-2; AltName: Full=Atrophin-1-interacting protein 1; AltN [NCBI NR] gi\|3411053\|gb\|AAC31124.1\| synaptic scaffolding molecule [Rattus norvegicus] [NCBI NR] gi\|16758422\|ref\|NP_446073.1\| membrane associated guanylate kinase, WW and PDZ domain containing 2 [Rattus norvegicus] [NCBI NR] Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 OS=Rattus norvegicus GN=Magi2 PE=1 SV=1 [Swiss-Prot] (O88382) Atrophin-1-interacting protein 1 (Membrane-associated guanylate kinase inverted-2) (MAGI-2) (Synaptic scaffolding molecule) (S-SCAM) [Swiss-Prot] Ensembl_locations(Chr-bp):4-8808894;4-8808894 Synaptic scaffolding molecule [hmr_yeast5_DM3-1_pombe.fasta] activin receptor interacting protein 1 [HMR_022704-rand.fasta] activin receptor interacting protein 1 [Rattus norvegicus]gi\|37537749\|sp\|O88382\|AIP1_RAT Atrophin-1 interacting protein 1 (Membrane associated guanylate kinase inverted-2) (MAGI-2) (Synaptic scaffolding molecule) (S-SCAM)gi\|7514091\|pir\|\|T14152 synaptic [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform 1 of Atrophin-1-interacting protein 1 [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_053621) activin receptor interacting protein 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform 1 of Atrophin-1 interacting protein 1 [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Synaptic-scaffolding molecule) (S-SCAM) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] membrane associated guanylate kinase, WW and PDZ domain containing 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] synaptic scaffolding molecule [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF ATROPHIN-1 INTERACTING PROTEIN 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] activin receptor interacting protein 1 [Rattus norvegicus] [nr-271106-contam.fasta] Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Synaptic scaffolding molecule) (S-SCAM) [nr-271106-contam.fasta] synaptic scaffolding protein S-SCAM - rat [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Magi2 Isoform 1 of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 [rat-ipi-250309-contam.fasta] Isoform 1 of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 OS=Rattus norvegicus GN=Magi2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1277 amino acids
Gene Ontology:
Cellular Component:	synaptosome [IEA] cell junction [IEA] protein complex [IDA] synapse [IEA] plasma membrane [IEA]
Biological Process:	intracellular signaling pathway [IPI] signal transduction [UNKNOWN]
Molecular Function:	phosphatase binding [UNKNOWN][IEA] protein binding [UNKNOWN][IEA][IPI] protein complex binding [IPI] signal transducer activity [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKSLKKKSH WTSKVHESVI GRNPEGQLGF ELKGGAENGQ FPYLGEVKPG KVAYESGSKL  60
   61 VSEELLLEVN ETPVAGLTIR DVLAVIKHCK DPLRLKCVKQ GGIVDKDLRH YLNLRFQKGS 120
  121 VDHELQQIIR DNLYLRTVPC TTRPHKEGEV PGVDYIFITV EDFMELEKSG ALLESGTYED 180
  181 NYYGTPKPPA EPAPLLLNVT DQILPGATPS AEGKRKRNKS VTNMEKASIE PPEEEEEERP 240
  241 VVNGNGVVIT PESSEHEDKS AGASGETPSQ PYPAPVYSQP EELKDQMDDT KSTKPEENED 300
  301 SDPLPDNWEM AYTEKGEVYF IDHNTKTTSW LDPRLAKKAK PAEECKENEL PYGWEKIDDP 360
  361 IYGTYYVDHI NRRTQFENPV LEAKRKLQQH NMPHTELGTK PLQAPGFREK PLFTRDASQL 420
  421 KGTFLSTTLK KSNMGFGFTI IGGDEPDEFL QVKSVIPDGP AAQDGKMETG DVIVYINEVC 480
  481 VLGHTHADVV KLFQSVPIGQ SVNLVLCRGY PLPFDPEDPA NSMVPPLAIM ERPPPVMVNG 540
  541 RHNYETYLEY ISRTSQSVPD ITDRPPHSLH SMPADGQLDG TYPPPVHDDN VSVASSGATQ 600
  601 AELMTLTIVK GAKGFGFTIA DSPTGQRVKQ ILDIQGCPGL CEGDLIVEIN QQNVQNLSHT 660
  661 EVVDILKDCP VGSETSLIIH RGGFFSPWKT PKPMVDRWEN QGSPQTSLSA PAVPQSLPFP 720
  721 PALHRSSFPD STEAFDPRKP DPYELYEKSR AIYESRQQVP PRTSFRMDSS GPDYKELDVH 780
  781 LRRMESGFGF RILGGDEPGQ PILIGAVIAM GSADRDGRLH PGDELVYVDG IPVAGKTHRY 840
  841 VIDLMHHAAR NGQVNLTVRR KVLCGGEPCP ENGRSPGSVS THHSSPRSDY ATYANSNHAA 900
  901 PSNNASPPEG FASHSLQTSD VIIHRKENEG FGFVIISSLN RPESGATITV PHKIGRIIDG 960
  961 SPADRCAKLK VGDRILAVNG QSIINMPHAD IVKLIKDAGL SVTLRIIPQE ELNNPTSAPS1020
 1021 SEKQSPMAQQ HSPLAQQHSP LAQPSPATPN SPVAQPAPPQ PLQLQGHENS YRSEVKARQD1080
 1081 VKPDIRQPPF TDYRQPPLDY RQPPGGDYSQ PSPLDYRQHS PDTRQYPLSD YRQPQDFDYF1140
 1141 TVDMEKGAKG FGFSIRGGRE YKMDLYVLRL AEDGPAIRNG RMRVGDQIIE INGESTRDMT1200
 1201 HARAIELIKS GGRRVRLLLK RGTGQVPEYG MVPSSLSMCM KSDKHGSPYF YLLGHPKDTT1260
 1261 NPTPGALPLP PPQACRK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: MAGI2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: