Protein Overview: EGLN2_RAT

General Information:
Name(s) found:	EGLN2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|61676841\|gb\|AAX51892.1\| HIF-1alpha prolyl-4-hydroxylase-1 [Rattus norvegicus] [NCBI NR] gi\|51858631\|gb\|AAH81858.1\| Egln2 protein [Rattus norvegicus] [NCBI NR] gi\|51854225\|ref\|NP_001004083.1\| EGL nine homolog 2 [Rattus norvegicus] [NCBI NR] gi\|50925525\|gb\|AAH78907.1\| EGL nine homolog 2 (C. elegans) [Rattus norvegicus] [NCBI NR] gi\|149056540\|gb\|EDM07971.1\| EGL nine homolog 2 (C. elegans), isoform CRA_a [Rattus norvegicus] [NCBI NR] Egl nine homolog 2 OS=Rattus norvegicus GN=Egln2 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):1-79735360;1-79743497 2-oxoglutarate-Fe [hmr_yeast5_DM3-1_pombe.fasta] EGL nine homolog 2 [Rattus norvegicus]gi\|51858631\|gb\|AAH81858.1\| Egln2 protein [Rattus norvegicus]gi\|50925525\|gb\|AAH78907.1\| EGL nine homolog 2 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 EGL nine homolog 2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] EGL nine homolog 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] EGL nine homolog 2 (C. elegans), isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] EGL nine homolog 2 (C. elegans) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] HIF-1alpha prolyl-4-hydroxylase-1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Egln2 protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 EGL NINE HOMOLOG 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Egln2 HIF-1alpha prolyl-4-hydroxylase-1 [rat-ipi-250309-contam.fasta] EGL nine homolog 2 (C. elegans) OS=Rattus norvegicus GN=Egln2 [011711_HMR.fasta] EGL nine homolog 2 (C. elegans) OS=Rattus norvegicus GN=Egln2 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	415 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN]
Biological Process:	response to hypoxia [UNKNOWN][IDA] positive regulation of protein catabolic process [UNKNOWN] cell redox homeostasis [UNKNOWN]
Molecular Function:	oxygen sensor activity [UNKNOWN] oxidoreductase activity [IDA] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSPCQPQAL NQALPQLPGS VSESLEPSRA RMGVESYLPC PLLPSYHRSG ASGEASAGNG  60
   61 TPRTTATATT TTASPLREGF GGQDGGELWP LQSEGAAALV TKECQRLAAQ GARPEAPKRK 120
  121 WAKDGGDAPS PSKRPWARQE NQEAKGESGV GCDSGGGSSN STTHSSGEAS SRLREEAQPS 180
  181 APERLALDYI VPCMRYYGIC VKDNFLGAVL GGRVLAEVEA LKWGGRLRDG QLVSQRAIPP 240
  241 RSIRGDQIAW VEGHEPGCRS IGALMAHVDA VIRHCAGRLG NYVINGRTKA MVACYPGNGL 300
  301 GYVRHVDNPH GDGRCITCIY YLNQNWDVKV HGGLLQIFPE GRPVVANIEP LFDRLLIFWS 360
  361 DRRNPHEVKP AYATRYAITV WYFDAKERAA ARDKYQLASG QKGVQVPVSQ PATPT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: EGLN2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: