Protein Overview: LDLR_RAT

General Information:
Name(s) found:	LDLR_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|56570\|emb\|CAA32001.1\| unnamed protein product [Rattus norvegicus] [NCBI NR] gi\|547842\|sp\|P35952.1\|LDLR_RAT RecName: Full=Low-density lipoprotein receptor; Short=LDL receptor; Flags: Precursor [NCBI NR] gi\|28461161\|ref\|NP_786938.1\| Low density lipoprotein receptor [Rattus norvegicus] [NCBI NR] Low-density lipoprotein receptor OS=Rattus norvegicus GN=Ldlr PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):8-20229366 Low-density lipoprotein receptor precursor [hmr_yeast5_DM3-1_pombe.fasta] Low density lipoprotein receptor; LDL receptor [HMR_022704-rand.fasta] Low density lipoprotein receptor [Rattus norvegicus]gi\|56570\|emb\|CAA32001.1\| unnamed protein product [Rattus norvegicus]gi\|547842\|sp\|P35952\|LDLR_RAT Low-density lipoprotein receptor precursor (LDL receptor) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Low-density lipoprotein receptor precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Low-density lipoprotein receptor precursor (LDL receptor) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Low density lipoprotein receptor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 LOW-DENSITY LIPOPROTEIN RECEPTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Ldlr Low-density lipoprotein receptor [rat-ipi-250309-contam.fasta] low density lipoprotein receptor precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Low-density lipoprotein receptor OS=Rattus norvegicus GN=Ldlr [011711_HMR.fasta] Low-density lipoprotein receptor OS=Rattus norvegicus GN=Ldlr PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	879 amino acids
Gene Ontology:
Cellular Component:	caveola [IDA] endosome [UNKNOWN][IEA] clathrin-coated endocytic vesicle membrane [UNKNOWN] coated pit [IEA] membrane [IEA] low-density lipoprotein particle [IEA] integral to membrane [IEA] endosome membrane [UNKNOWN] plasma membrane [UNKNOWN][IDA]
Biological Process:	low-density lipoprotein particle clearance [UNKNOWN][IEA] response to estrogen stimulus [IEP] cholesterol metabolic process [UNKNOWN][IEA] steroid metabolic process [IEA] lipoprotein metabolic process [UNKNOWN] endocytosis [IEA][IMP] aging [IEP] response to hormone stimulus [IEP] lipoprotein catabolic process [UNKNOWN][IEA] cholesterol homeostasis [UNKNOWN][IEA] lipid transport [IEA] lipid metabolic process [UNKNOWN] response to estradiol stimulus [IEP] intestinal cholesterol absorption [UNKNOWN][IEA] response to glucagon stimulus [IEP] cholesterol transport [UNKNOWN]
Molecular Function:	protein binding [UNKNOWN][IPI] very-low-density lipoprotein receptor activity [UNKNOWN][IEA] calcium ion binding [IEA] low-density lipoprotein receptor activity [UNKNOWN][IMP][TAS] receptor activity [IEA] low-density lipoprotein binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTADLMLRW AIALLLAAAG VAAEDSCGKN EFQCRDGKCI VSKWVCDGSR ECPDGSDESP  60
   61 ETCMSVTCRS GEFSCGGRVS RCIPDSWRCD GRTDCENGSD ELDCSPKTCS LDEFRCQDGK 120
  121 CISRQFVCDQ DWDCLDGSDE AHCAATTCGP AHFRCNSSSC IPSLWACDGD RDCDDGSDEW 180
  181 PQNCGAEDTA AEVVSSPCSS LEFHCGSSEC IHRSWVCDGA ADCKDKSDEE NCAVTTCRPD 240
  241 EFQCADGSCI HGSRQCDREH DCKDMSDELG CINVTQCDGP NKFKCHSGEC ISLDKVCNSA 300
  301 RDCRDWSDEP IKECKTNECL DNNGGCSHIC KDLKIGYECL CPSGFRLVDG HQCEDIDECQ 360
  361 EPDTCSQLCV NLEGSFKCEC RAGFHMDPHT RVCKAVGSIG FLLFTNRHEV RKMTLDRSEY 420
  421 TSLIPNLKNV VALDTEVANN RIYWSDLSQR KIYSAVMDQG TSLSYDAIIS GDLHAPDGLA 480
  481 VDWIHGNIYW TDSVPGTVSV ADTKGVRRRT LFREKGSRPR AIVVDPVHGF MYWTDWGTPA 540
  541 KIKKGGLNGV DIYSLVTEDI QWPNGITLDL PSGRLYWVDS KLHSISSIDV NGGGRKTILE 600
  601 DEKQLAHPFS LAIYEDKVYW TDVLNEAIFS ANRLTGSDVN LVAKNLMSPE DIVLFHNVTQ 660
  661 PRGVNWCEAT VLPNGGCQYM CLPAPQISAH SPKFTCACPD GMLLAKDMRS CLPEVDTVPT 720
  721 TQGTSTIGPV VTTSAAVSLK RKEDPSATRH KEDPSATRHN EDPSATSTSR QPGDTPELST 780
  781 VESVTVSSQV QGDMAGRGDE VQRHGVGFLS IFLPIALVAL LVFGAILLWR NWRLRNINSI 840
  841 NFDNPVYQKT TEDEIHICRS QDGYTYPSRQ MVSLEDDVA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: LDLR_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: