Protein Overview: NHRF1_RAT

General Information:
Name(s) found:	NHRF1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8132349\|gb\|AAF73258.1\|AF154336_1 ERM-binding phosphoprotein [Rattus norvegicus] [NCBI NR] gi\|41688553\|sp\|Q9JJ19.3\|NHRF1_RAT RecName: Full=Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Short=NHERF-1; AltName: Full=Ezrin-radixin-moesin-binding phosphoprotein 50; Short=EBP50; AltName: Full=Regulatory cofactor of Na(+)/H(+) exchanger; AltName: [NCBI NR] gi\|149054746\|gb\|EDM06563.1\| solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1 [Rattus norvegicus] [NCBI NR] gi\|11024674\|ref\|NP_067605.1\| ERM-binding phosphoprotein [Rattus norvegicus] [NCBI NR] Na(+)/H(+) exchange regulatory cofactor NHE-RF1 OS=Rattus norvegicus GN=Slc9a3r1 PE=1 SV=3 [Swiss-Prot] (Q9JJ19) Ezrin-radixin-moesin binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 iso [Swiss-Prot] Ezrin-radixin-moesin-binding phosphoprotein 50 OS=Rattus norvegicus GN=Slc9a3r1 PE=1 SV=3 [Swiss-Prot] Ensembl_locations(Chr-bp):10-103227620 ERM-binding phosphoprotein [hmr_yeast5_DM3-1_pombe.fasta] ERM-binding phosphoprotein [HMR_022704-rand.fasta] ERM-binding phosphoprotein [Rattus norvegicus]gi\|41688553\|sp\|Q9JJ19\|NHR1_RAT Ezrin-radixin-moesin binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen [nrdb_11152004_Chlamydomonas] (NM_021594) ERM-binding phosphoprotein [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Ezrin-radixin-moesin binding phosphoprotein 50 [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] ERM-binding phosphoprotein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN 50 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory f [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Slc9a3r1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 [rat-ipi-250309-contam.fasta] Na(+)/H(+) exchange regulatory cofactor NHE-RF1 OS=Rattus norvegicus GN=Slc9a3r1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	356 amino acids
Gene Ontology:
Cellular Component:	apical part of cell [UNKNOWN] intracellular membrane-bounded organelle [UNKNOWN][IEA] endomembrane system [IEA] plasma membrane [UNKNOWN][IEA] apical plasma membrane [UNKNOWN][IEA]
Biological Process:	Wnt receptor signaling pathway [IEA] cellular phosphate ion homeostasis [UNKNOWN][IEA]
Molecular Function:	protein binding [UNKNOWN][IPI] protein C-terminus binding [IEA] PDZ domain binding [UNKNOWN][IEA] beta-2 adrenergic receptor binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSADAAAGEP LPRLCCLEKG PNGYGFHLHG EKGKVGQFIR LVEPGSPAEK SGLLAGDRLV  60
   61 EVNGENVEKE THQQVVSRIR AALNAVRLLV VDPETDEQLK KLGVPIREEL LRAQEKSEHT 120
  121 EPPAAADTKK AGDQNEAEKS HLERCELRPR LCTMKKGPNG YGFNLHSDKS KPGQFIRAVD 180
  181 PDSPAEASGL RAQDRIVEVN GVCMEGKQHG DVVSAIKAGG DEAKLLVVDK ETDEFFKKCR 240
  241 VTPSQEHLDG PLPEPFSNGE IQKENSREAL VEPASESPRP ALARSASSDT SEELNAQDSP 300
  301 KRHDSTEPSS TSSSSDPILD FNISLAVAKE RAHQKRSSKR APQMDWSKKN ELFSNL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: NHRF1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: