Protein Overview: RPA1_RAT

General Information:
Name(s) found:	RPA1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|T14103 probable DNA-directed RNA polymerase (EC 2.7.7.6) I large chain - rat [NCBI NR] gi\|3914802\|sp\|O54889.1\|RPA1_RAT RecName: Full=DNA-directed RNA polymerase I subunit RPA1; Short=RNA polymerase I subunit A1; AltName: Full=DNA-directed RNA polymerase I subunit A; AltName: Full=DNA-directed RNA polymerase I largest subunit; AltName: Full= [NCBI NR] gi\|2739050\|gb\|AAB94601.1\| RNA polymerase I 194 kDa subunit [Rattus norvegicus] [NCBI NR] gi\|13929086\|ref\|NP_113960.1\| DNA-directed RNA polymerase I A [Rattus norvegicus] [NCBI NR] DNA-directed RNA polymerase I subunit RPA1 OS=Rattus norvegicus GN=Polr1a PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):4-108615635;4-108615635 DNA-directed RNA polymerase I largest subunit [hmr_yeast5_DM3-1_pombe.fasta] RNA polymerase 1-4; RNA polymerase I (194 kDa subunit) [HMR_022704-rand.fasta] RNA polymerase 1-4 [Rattus norvegicus]gi\|2739050\|gb\|AAB94601.1\| RNA polymerase I 194 kDa subunit [Rattus norvegicus]gi\|7514047\|pir\|\|T14103 probable DNA-directed RNA polymerase (EC 2.7.7.6) I large chain - ratgi\|3914802\|sp\|O54889\|RPA1_RAT DNA-directed R [nrdb_11152004_Chlamydomonas] Tax_Id=10116 DNA-directed RNA polymerase I largest subunit [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031772) RNA polymerase I (194 kDa subunit) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (DNA-directed RNA polymerase I subunit A) (DNA-directed RNA polymerase I largest subunit) (RNA polymerase I 194 kDa subunit) (RPA194) (A194) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] RNA polymerase 1-4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] RNA polymerase I 194 kDa subunit [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 DNA-DIRECTED RNA POLYMERASE I LARGEST SUBUNIT [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] polymerase (RNA) I polypeptide A [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] DNA-directed RNA polymerase I largest subunit (RNA polymerase I 194 kDa subunit) (RPA194) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Polr1a DNA-directed RNA polymerase I subunit RPA1 [rat-ipi-250309-contam.fasta] DNA-directed RNA polymerase I subunit RPA1 OS=Rattus norvegicus GN=Polr1a [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1716 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA] DNA-directed RNA polymerase I complex [UNKNOWN][IDA] nucleolus [IEA] nucleoplasm [UNKNOWN]
Biological Process:	transcription [IEA] rRNA transcription [IDA]
Molecular Function:	DNA binding [IEA] zinc ion binding [IEA] nucleotidyltransferase activity [IEA] DNA-directed RNA polymerase activity [IDA] protein binding [UNKNOWN][IEA] metal ion binding [IEA] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLASKHTPWR RLQGISFGMY SAEELKKLSV KSITNPRYVD SLGNPSADGL YDLALGPADS  60
   61 KEVCSTCVQD FNNCSGHLGH IDLPLTVYNP LLFDKLYLLL RGSCLNCHML TCPRAAIHLL 120
  121 VCQLKVLDVG ALQAVYELER ILSRFLEETS DPSAFEIQEE LEEYTSKILQ NNLLGSQGAH 180
  181 VKNVCESRSK LVAHFWKTHM AAKRCPHCKT GRSVVRKEHN SKLTITYPAM VHKKSGQKDA 240
  241 ELPEGAPAAP GIDEAQMGKR GYLTPSSAQE HLFAIWKNEG FFLNYLFSGL DDIGPESSFN 300
  301 PSMFFLDFIV VPPSRYRPIN RLGDQMFTNG QTVNLQAVMK DAVLIRKLLA VMAQEQKLPC 360
  361 EMTEITIDKE NDSSGAIDRS FLSLLPGQSL TDKLYNIWIR LQSHVNIVFD SDMDKLMLEK 420
  421 YPGIRQILEK KEGLFRKHMM GKRVDYAARS VICPDMYINT NEIGIPMVFA TKLTYPQPVT 480
  481 PWNVQELRQA VINGPNVHPG ASMVINEDGS RTALSAVDAT QREAVAKQLL TPSTGIPKPQ 540
  541 GAKVVCRHVK NGDILLLNRQ PTLHRPSIQA HRAHILPEEK VLRLHYANCK AYNADFDGDE 600
  601 MNAHFPQSEL GRAEAYVLAC TDQQYLVPKD GQPLAGLIQD HMVSGANMTI RGCFFTREQY 660
  661 MELVYRGLTD KVGRVKLFPP AILKPFPLWT GKQVVSTLLI NIIPEDYTPL NLTGKAKIGS 720
  721 KAWVKEKPRP VPDFDPDSMC ESQVIIREGE LLCGVLDKAH YGSSAYGLVH CCYEIYGGET 780
  781 SGRVLTCLAR LFTAYLQLYR GFTLGVEDIL VKPNADVMRQ RIIEESTQCG PRAVRAALNL 840
  841 PEAASCDEIQ GKWQDAIWRK DQRDFNMIDM KFKEEVNHYS NEINKACMPF GLHRQFPENN 900
  901 LQMMVQSGAK GSTVNTMQIS CLLGQIELEG RRPPLMASGK SLPCFEPYEF TPRAGGFVTG 960
  961 RFLTGIRPPE FFFHCMAGRE GLVDTAVKTS RSGYLQRCII KHLEGLVIQY DLTVRDSDGS1020
 1021 VVQFLYGEDG LDIPKTQFLQ PKQFPFLASN YEVIMKSKHL HEVLSRADPQ KVLRHFRAIK1080
 1081 KWHHRHSSAL LRKGAFLSFS QKIQAAVKAL NLEGKTQNGR SPETQQMLQM WHELDEQSRR1140
 1141 KYQKRAAPCP DPSLSVWRPD IHFASVSETF EKKIDDYSQE WAAQAEKSHN RSELSLDRLR1200
 1201 TLLQLKWQRS LCDPGEAVGL LAAQSIGEPS TQMTLNTFHF AGRGEMNVTL GIPRLREILM1260
 1261 VASANIKTPM MSVPVFNTKK ALRRVKSLKK QLTRVCLGEV LQKVDIQESF CMGEKQNKFR1320
 1321 VYELRFQFLP HAYYQQEKCL RPEDILHFME TRFFKLLMEA IKKKNSKASA FRSVNTRRAT1380
 1381 QKDLDDTEDS GRNRREEERD EEEEGNIVDA EAEEGDADAS DTKRKEKQEE EVDYESEEEG1440
 1441 EEEEEEDVQE EENIKGEGAH QTHEPDEEEG SGLEEESSQN PPCRHSRPQG AEAMERRIQA1500
 1501 VRESHSFIED YQYDTEESLW CQVTVKLPLM KINFDMSSLV VSLAHNAIVY TTKGITRCLL1560
 1561 NETINSKNEK EFVLNTEGIN LPELFKYSEV LDLRRLYSND IHAVANTYGI EAALRVIEKE1620
 1621 IKDVFAVYGI AVDPRHLSLV ADYMCFEGVY KPLNRFGIQS SSSPLQQMTF ETSFQFLKQA1680
 1681 TMMGSHDELK SPSACLVVGK VVKGGTGLFE LKQPLR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: RPA1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: