Protein Overview: D2HDH_RAT

General Information:
Name(s) found:	D2HDH_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|97048478\|sp\|P84850.1\|D2HDH_RAT RecName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial; Flags: Precursor [NCBI NR] gi\|183986286\|gb\|AAI66559.1\| D2hgdh protein [Rattus norvegicus] [NCBI NR] gi\|109486381\|ref\|XP_217474.4\| PREDICTED: similar to D-2-hydroxyglutarate dehydrogenase [Rattus norvegicus] [NCBI NR] D-2-hydroxyglutarate dehydrogenase, mitochondrial OS=Rattus norvegicus GN=D2hgdh PE=3 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):9-101528942 [hmr_yeast5_DM3-1_pombe.fasta] Tax_Id=10116 D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] D2hgdh protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] PREDICTED: similar to D-2-hydroxyglutarate dehydrogenase [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=D2hgdh D-2-hydroxyglutarate dehydrogenase, mitochondrial [rat-ipi-250309-contam.fasta] D-2-hydroxyglutarate dehydrogenase, mitochondrial OS=Rattus norvegicus GN=D2hgdh [011711_HMR.fasta] D2hgdh protein OS=Rattus norvegicus GN=D2hgdh PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta] Isoform of P84850, D-2-hydroxyglutarate dehydrogenase, mitochondrial OS=Rattus norvegicus GN=D2hgdh PE=1 SV=1 [RAT.fasta.20160308]
Organism:	Rattus norvegicus
Length:	535 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA]
Biological Process:	response to manganese ion [IDA] response to zinc ion [IDA] response to calcium ion [IDA] response to cobalt ion [IDA] cellular protein metabolic process [IDA] response to magnesium ion [IDA] oxidation reduction [IEA]
Molecular Function:	protein binding [UNKNOWN][IEA] (R)-2-hydroxyglutarate dehydrogenase activity [IDA] oxidoreductase activity [IEA] FAD binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLHLVPRWS ASLFRASPRW KKTYSQRASA QLKWLGCPRS VYSPLACRAY SKVSGSPEVM  60
   61 LTPERYPVQR LPFSTVSEED LAAFECIIPG RVITDPEQLQ TCNVDWLRTV RGCSKVLLRP 120
  121 QTSEEVSQIL RHCYKRNLAV NPQGGNTGMV GGSVPVFDEV ILSTALMNQV ISFHDVSGIL 180
  181 VCQAGCVLEE LSRYVQERDF IMPLDLGAKG SCHIGGNVAT NAGGLRFLRY GSLRGTVLGL 240
  241 EVVLADGTIL NCLTSLRKDN TGYDLKQMFI GSEGTLGVIT AVSIVCPPRP KAVNVAFLGC 300
  301 PGFTEVLQTF RTCKGQLGEI LSAFEFMDAE CMQLVGQHLH LTNPVQESPF YVLVETSGSS 360
  361 AGHDAEKLTN VLEQVLNSGL VIDGTMATDQ RKVQMLWALR ERITEALSRD GYVFKYDLSL 420
  421 PVERLYDLVI DLRTRLGPRA KHVVGYGHLG DGNLHLNVTA EAFSQELLGA LEPYVYAWTA 480
  481 EQRGSVSAEH GLGFKKKNVL GYSKPPVAVK LMQQLKAMLD PKGILNPYKT LPARA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Protein Overview: D2HDH_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: