Protein Overview: MADD_RAT

General Information:
Name(s) found:	MADD_RAT [Swiss-Prot]
Description(s) found: Found 18 descriptions. SHOW ALL	MAP kinase-activating death domain protein OS=Rattus norvegicus GN=Madd PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	1602 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [UNKNOWN][ISS]
Biological Process:	activation of MAPK activity [UNKNOWN][ISS] regulation of apoptosis [UNKNOWN][ISS] regulation of cell cycle [UNKNOWN][ISS]
Molecular Function:	protein binding [UNKNOWN] guanyl-nucleotide exchange factor activity [IEA] Rab guanyl-nucleotide exchange factor activity [UNKNOWN][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQKKFCPRL LDYLVIVGAR HPSSDSVAQT PELLRRYPLE DHPEFPLPPD VVFFCQPEGC  60
   61 LSVRQRRMSL RDDTSFVFTL TDKDTGVTRY GICVNFYRSF QKRMPKEKAE GGAGPRGKEG 120
  121 AHAPCASEEA ATESSESGST LQPPSADSTP DVNQSPRGKR RAKAGNRSRN STLTSLCVLS 180
  181 HYPFFSTFRE CLYTLKRLVD CCSERLLGKK PGIPRGVQRD TMWRIFTGSL LVEEKSSALL 240
  241 HDLREIEAWI YRLLRSPVPV SGQKRVDIEV LPQEVQQALT FALPDPSRFT LVDFPLHLPL 300
  301 ELLGVDACLQ VLTCILLEHK VVLQSRDYNA LSMSVMAFVA MIYPLEYMFP VIPLLPTCMA 360
  361 SAEQLLLAPT PYIIGVPASF FLYKLDFKMP DDVWLVDLDS NRVIAPTNAE VLPILPEPES 420
  421 LELKKHLKQA LASMSLNTQP ILNLEKFHEG QETPLLLGRF SNDLQSTPST EFNPLIYGND 480
  481 VDSVDVATRV AMVRFFNSAN VLQGFQMHTR TLRLFPRPVV AFQAGSFLAS RPRQTPFAEK 540
  541 LARTQAVEYF GEWILNPSNY AFQRIHNNTF DPALIGDKPK WYAHQLQPIH YRVYDSNSQL 600
  601 AEALSVPPER DSESDPTDDS GSDSMDYDDS SSSYSSLGDF VSEMMKCDIN GDTPNVDPLT 660
  661 HAALGDASEV EIDELQPQKE GEEPGPDSEN SQENLPLRSS SSTTASSSPS TIVHGAHSEP 720
  721 ADSTEVGDKA ATGISKPLPP VPPSICKSTV DRRQTETGEG SVCQRTYDHP YFEPQYGSPA 780
  781 EEDDDEQGES YTPRFSQHAS GSRAQKLLRP NSLKLASDSD AESDSRASSP NSTVSNNSTE 840
  841 GFGGIMSFAS SLYRNHSTSF SLSNLTLPTK GAREKTTPFP SLKGNRRALV DQKSSVIKHS 900
  901 PTVKREPPSP QGRSSNSSEN QQFLKEVVHS VLDGQGVGWL NMKKVRRLLE SEQLRVFVLS 960
  961 KLSRAVQSED DARQDVIQDV EISRKVYKGM LDLLKCTVLS LEQSYAHAGL GGMASIFGLL1020
 1021 EIAQTHYYSK EPDKRKRSPT ENVNTPVGKD PGLAGRGDPK AMAQLRVPQL GPRAPSATGR1080
 1081 GPKELDTRSL KEENFVASVG PEVIKPVFDL GETEEKKSQI SADSGVSLAS ASQRTDQDSV1140
 1141 IGVSPAVMIR SSSQDSEVSN SSGETLGADS DLSSNAGDGP GGEGSAHLAS SRATLSDSEI1200
 1201 ETNSATSTIF GKAHSLKPKE KPASSPVRSS EDVSQRVYLY EGLLGRDKGS MWDQLEDAAM1260
 1261 ETFSISKERS TLWDQMQFWE DAFLDAVMLE REGMGMDQGP QEMIDRYLSL GEHDRKRLED1320
 1321 DEDRLLATLL HNLISYMLLM KVNKNDIRKK VRRLMGKSHV GLVYSQQINE VLDQLTNLNG1380
 1381 RDLSIRSSGS RHMKKQTFVV HAGTDTNGDI FFMEVCDDCV VLRSNIGTVY ERWWYEKLIN1440
 1441 MTYCPKTKVL CLWRRNGSET QLNKFYTKKC RELYYCVKDS MERAAARQQS IKPGPELGGE1500
 1501 FPVQDMKTGE GGLLQVTLEG INLKFMHNQV FIELNHIKKC NTVRGVFVLE EFVPEIKEVV1560
 1561 SHKYKTPMAH EICYSVLCLF SYVAAVRSSE EDLRTPPRPV SS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.62

Protein Overview: MADD_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: