Protein Overview: EDNRA_RAT

General Information:
Name(s) found:	EDNRA_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|399458\|sp\|P26684.2\|EDNRA_RAT RecName: Full=Endothelin-1 receptor; AltName: Full=Endothelin A receptor; Short=ET-A; Flags: Precursor [NCBI NR] (P26684) Endothelin-1 receptor precursor (Endothelin A receptor) (ET-A) [Swiss-Prot] Endothelin-1 receptor OS=Rattus norvegicus GN=Ednra PE=2 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):19-31563782 Endothelin-1 receptor precursor [hmr_yeast5_DM3-1_pombe.fasta] endothelin receptor ETA, ETR ETA [rats, lung, Peptide, 426 aa]gi\|399458\|sp\|P26684\|ET1R_RAT Endothelin-1 receptor precursor (Endothelin A receptor) (ET-A) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Endothelin-1 receptor precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Endothelin-1 receptor precursor (Endothelin A receptor) (ET-A) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 ENDOTHELIN-1 RECEPTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Ednra Endothelin-1 receptor [rat-ipi-250309-contam.fasta] Endothelin-1 receptor OS=Rattus norvegicus GN=Ednra [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	426 amino acids
Gene Ontology:
Cellular Component:	T-tubule [IDA] nuclear membrane [IDA] membrane [IDA] integral to membrane [IEA] plasma membrane [IEA]
Biological Process:	signal transduction [IEA] neural crest cell development [UNKNOWN][IEA] positive regulation of inflammatory response [IMP] positive regulation of calcium ion transport [IMP] negative regulation of cAMP biosynthetic process [UNKNOWN][IEA] vasoconstriction [UNKNOWN][IMP] respiratory gaseous exchange [UNKNOWN][IEA] response to morphine [IMP] positive regulation of release of sequestered calcium ion into cytosol [IMP] activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway [IMP] [NOT]regulation of blood pressure [UNKNOWN] elevation of cytosolic calcium ion concentration [IDA] heart development [UNKNOWN][IEA] response to hypoxia [UNKNOWN][IEA] patterning of blood vessels [UNKNOWN][IEA] in utero embryonic development [UNKNOWN][IEA] elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger [IMP] positive regulation of protein amino acid phosphorylation [IMP] artery smooth muscle contraction [UNKNOWN][IEA] glucose transport [UNKNOWN][IEA] regulation of epithelial cell proliferation [IMP]
Molecular Function:	G-protein coupled receptor activity [IEA] endothelin-A receptor activity [IDA] protein binding [UNKNOWN][IEA] receptor activity [IEA] endothelin receptor activity [UNKNOWN][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVLCFLASF WLALVGGAIA DNAERYSANL SSHVEDFTPF PGTEFNFLGT TLQPPNLALP  60
   61 SNGSMHGYCP QQTKITTAFK YINTVISCTI FIVGMVGNAT LLRIIYQNKC MRNGPNALIA 120
  121 SLALGDLIYV VIDLPINVFK LLAGRWPFDH NDFGVFLCKL FPFLQKSSVG ITVLNLCALS 180
  181 VDRYRAVASW SRVQGIGIPL ITAIEIVSIW ILSFILAIPE AIGFVMVPFE YKGEQHRTCM 240
  241 LNATTKFMEF YQDVKDWWLF GFYFCMPLVC TAIFYTLMTC EMLNRRNGSL RIALSEHLKQ 300
  301 RREVAKTVFC LVVIFALCWF PLHLSRILKK TVYDEMDKNR CELLSFLLLM DYIGINLATM 360
  361 NSCINPIALY FVSKKFKNCF QSCLCCCCHQ SKSLMTSVPM NGTSIQWKNQ EQNHNTERSS 420
  421 HKDSMN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: EDNRA_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: