Protein Overview: SERA_RAT

General Information:
Name(s) found:	SERA_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|7688285\|emb\|CAB89828.1\| 3-phosphoglycerate dehydrogenase [Rattus norvegicus] [NCBI NR] gi\|55562727\|gb\|AAH86327.1\| Phgdh protein [Rattus norvegicus] [NCBI NR] gi\|3122856\|sp\|O08651.3\|SERA_RAT RecName: Full=D-3-phosphoglycerate dehydrogenase; Short=3-PGDH [NCBI NR] gi\|1944614\|emb\|CAA66374.1\| D-3-phosphoglycerate dehydrogenase [Rattus norvegicus] [NCBI NR] gi\|149030528\|gb\|EDL85565.1\| 3-phosphoglycerate dehydrogenase, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149030526\|gb\|EDL85563.1\| 3-phosphoglycerate dehydrogenase, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|13928850\|ref\|NP_113808.1\| phosphoglycerate dehydrogenase [Rattus norvegicus] [NCBI NR] D-3-phosphoglycerate dehydrogenase OS=Rattus norvegicus GN=Phgdh PE=1 SV=3 [Swiss-Prot] Ensembl_locations(Chr-bp):2-188317547 D-3-phosphoglycerate dehydrogenase [hmr_yeast5_DM3-1_pombe.fasta] 3-phosphoglycerate dehydrogenase [HMR_022704-rand.fasta] Phgdh protein [Rattus norvegicus]gi\|13928850\|ref\|NP_113808.1\| 3-phosphoglycerate dehydrogenase [Rattus norvegicus]gi\|7688285\|emb\|CAB89828.1\| 3-phosphoglycerate dehydrogenase [Rattus norvegicus]gi\|1944614\|emb\|CAA66374.1\| D-3-phosphoglycerate dehydrogena [nrdb_11152004_Chlamydomonas] (NM_031620) 3-phosphoglycerate dehydrogenase [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Ensembl_locations(Chr-bp):2-188317547 D-3-phosphoglycerate dehydrogenase [EBI-IPI_Drosophila_na_12-13-2007_con_reversed.fasta] D-3-phosphoglycerate dehydrogenase (3-PGDH) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 3-phosphoglycerate dehydrogenase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 3-phosphoglycerate dehydrogenase, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] D-3-phosphoglycerate dehydrogenase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Phgdh protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 3-PHOSPHOGLYCERATE DEHYDROGENASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] phosphoglycerate dehydrogenase [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Phgdh D-3-phosphoglycerate dehydrogenase [rat-ipi-250309-contam.fasta] D-3-phosphoglycerate dehydrogenase OS=Rattus norvegicus GN=Phgdh [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	533 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	neural tube development [UNKNOWN][IEA] neuron projection development [UNKNOWN][IEA] glutamine metabolic process [UNKNOWN][IEA] L-serine metabolic process [UNKNOWN] cell cycle process [UNKNOWN][IEA] L-serine biosynthetic process [IEA] neurogenesis [UNKNOWN][IEA] glial cell development [UNKNOWN][IEA] gamma-aminobutyric acid metabolic process [UNKNOWN][IEA] glycine metabolic process [UNKNOWN][IEA] threonine metabolic process [UNKNOWN][IEA] spinal cord development [UNKNOWN][IEA] regulation of gene expression [UNKNOWN][IEA] taurine metabolic process [UNKNOWN][IEA] oxidation reduction [IEA] serine family amino acid biosynthetic process [TAS]
Molecular Function:	oxidoreductase activity [IEA] cofactor binding [IEA] NAD or NADH binding [IEA] phosphoglycerate dehydrogenase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFANLRKIL ISDSLDPCCR KILQDGGLQV VEKQNLSKEE LIAELQDCEG LIVRSATKVT  60
   61 ADVINAAEKL QVVGRAGTGV DNVDLEAATR KGVLVMNTPN GNSLSAAELT CGMLMCLARQ 120
  121 IPQATASMKD GKWDRKKFMG TELNGKTLGI LGLGRIGREV AARMQAFGMK TVGYDPIISP 180
  181 EVAASFGVQQ LPLEEIWPLC DFITVHTPLL PSTTGLLNDS TFAQCKKGVR VVNCARGGIV 240
  241 DEGALLRALQ SGQCAGAALD VFTEEPPRDR ALVDHENVIS CPHLGASTKE AQSRCGEEIA 300
  301 VQFVDMVKGK SLTGVVNAQA LTSAFSPHTK PWIGLAEALG TLMHAWAGSP KGTIQVVTQG 360
  361 TSLKNAGTCL SPAVIVGLLR EASKQADVNL VNAKLLVKEA GLNVTTSHSP GVPGEQGIGE 420
  421 CLLTVALAGA PYQAVGLVQG TTPMLQMLNG AVFRPEVPLR RGQPLLLFRA QPSDPVMLPT 480
  481 MIGLLAEAGV QLLSYQTSKV SDGDTWHVMG LSSLLPSLDA WKQHVSEAFQ FCF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.92

Protein Overview: SERA_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: