Protein Overview: TMC1_MOUSE

General Information:
Name(s) found:	TMC1_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|24212480\|sp\|Q8R4P5.1\|TMC1_MOUSE RecName: Full=Transmembrane channel-like protein 1; AltName: Full=Transmembrane cochlear-expressed protein 1; AltName: Full=Beethoven protein; AltName: Full=Deafness protein [NCBI NR] gi\|20127392\|ref\|NP_083229.1\| transmembrane channel-like gene family 1 [Mus musculus] [NCBI NR] gi\|19223981\|gb\|AAL86400.1\|AF417579_1 transmembrane channel-like protein 1 [Mus musculus] [NCBI NR] gi\|148709633\|gb\|EDL41579.1\| transmembrane channel-like gene family 1 [Mus musculus] [NCBI NR] Transmembrane channel-like protein 1 OS=Mus musculus GN=Tmc1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):19-20065254 transmembrane, cochlear expressed 1 [hmr_yeast5_DM3-1_pombe.fasta] transmembrane channel-like gene family 1; deafness; transmembrane, cochlear expressed 1 [HMR_022704-rand.fasta] Splice Isoform 1 of Transmembrane cochlear-expressed protein 1 [ipi.MOUSE.v3.06.fasta] transmembrane channel-like gene family 1 [Mus musculus]gi\|19223981\|gb\|AAL86400.1\| transmembrane channel-like protein 1 [Mus musculus]gi\|24212480\|sp\|Q8R4P5\|TMC1_MOUSE Transmembrane cochlear-expressed protein 1 (Beethoven protein) (Deafness protein) [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Splice Isoform 1 of Transmembrane cochlear-expressed protein 1 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_028953) transmembrane, cochlear expressed 1; deafness [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] transmembrane channel-like gene family 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Transmembrane channel-like protein 1 (Transmembrane cochlear-expressed protein 1) (Beethoven protein) (Deafness protein) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] transmembrane channel-like protein 1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Tmc1 Isoform 1 of Transmembrane channel-like protein 1 [mouse-ipi-250309-contam.fasta] Transmembrane cochlear-expressed protein 1 (Beethoven protein) (Deafness protein) [nr-271106-contam.fasta] Tax_Id=10090 Gene_Symbol=Tmc1 Isoform 1 of Transmembrane channel-like protein 1 ENSMUSG00000024749 IPI00230747 IPI00331320 IPI00461216 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00331320.3\|SWISS-PROT:Q8R4P5-1\|TREMBL:Q8C5T3\|ENSEMBL:ENSMUSP00000040859\|REFSEQ:NP_083229 Tax_Id=10090 Gene_Symbol=Tmc1 Isoform 1 of Transmembrane channel-like protein 1 [ipi.MOUSE.fasta.20090209] Isoform 1 of Transmembrane channel-like protein 1 OS=Mus musculus GN=Tmc1 [011711_HMR.fasta] sp\|Q8R4P5\|TMC1_MOUSE Transmembrane channel-like protein 1 OS=Mus musculus GN=Tmc1 PE=1 SV=1 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	757 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA]
Biological Process:	sensory perception of sound [IMP]
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLQIQVEEKE EDTEESSSEE EEDKLPRRES LRPKRKRTRD VINEDDPEPE PEDEETRKAR  60
   61 EKERRRRLRR GAEEEEEIDE EELERLKALL DENRQMIATV KCKPWKMEKK IEVLKEAKKF 120
  121 VSENEGALGK GKGKKWFAFK MMMAKKWAKF LRDFENFKAA CVPWENKIKA IESQFGSSVA 180
  181 SYFLFLRWMY GVNMVLFVLT FSLIMLPEYL WGLPYGSLPR KTVPRAEEAS AANFGVLYDF 240
  241 NGLAQYSVLF YGYYDNKRTI GWLNFRLPLS YFLVGIMCIG YSFLVVLKAM TKNIGDDGGG 300
  301 DDNTFNFSWK VFCSWDYLIG NPETADNKFN SITMNFKEAI IEERAAQVEE NIHLIRFLRF 360
  361 LANFFVFLTL GASGYLIFWA VKRSQEFAQQ DPDTLGWWEK NEMNMVMSLL GMFCPTLFDL 420
  421 FAELEDYHPL IALKWLLGRI FALLLGNLYV FILALMDEIN NKIEEEKLVK ANITLWEANM 480
  481 IKAYNESLSG LSGNTTGAPF FVHPADVPRG PCWETMVGQE FVRLTVSDVL TTYVTILIGD 540
  541 FLRACFVRFC NYCWCWDLEY GYPSYTEFDI SGNVLALIFN QGMIWMGSFF APSLPGINIL 600
  601 RLHTSMYFQC WAVMCCNVPE ARVFKASRSN NFYLGMLLLI LFLSTMPVLY MIVSLPPSFD 660
  661 CGPFSGKNRM FEVIGETLEH DFPSWMAKIL RQLSNPGLVI AVILVMVLTI YYLNATAKGQ 720
  721 KAANLDLKKK MKQQALENKM RNKKMAAARA AAAAGGQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: TMC1_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: