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Protein Overview: MD2L1_MOUSE

General Information:
Name(s) found: MD2L1_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|7769762|gb|AAF69525.1|AF261919_1 spindle assembly checkpoint protein [Mus musculus] [NCBI NR]
  • gi|57242953|gb|AAH89012.1| MAD2 mitotic arrest deficient-like 1 (yeast) [Mus musculus] [NCBI NR]
  • gi|31543218|ref|NP_062372.2| MAD2 mitotic arrest deficient-like 1 [Mus musculus] [NCBI NR]
  • gi|26350121|dbj|BAC38700.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|148666369|gb|EDK98785.1| mCG125314, isoform CRA_a [Mus musculus] [NCBI NR]
  • gi|12849432|dbj|BAB28338.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|12643257|sp|Q9Z1B5.2|MD2L1_MOUSE RecName: Full=Mitotic spindle assembly checkpoint protein MAD2A; AltName: Full=MAD2-like 1 [NCBI NR]
  • Mitotic spindle assembly checkpoint protein MAD2A OS=Mus musculus GN=Mad2l1 PE=1 SV=2 [Swiss-Prot]
  • (Q9Z1B5) Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) [Swiss-Prot]
  • Ensembl_locations(Chr-bp):6-66847876 Mitotic spindle assembly checkpoint protein MAD2A [hmr_yeast5_DM3-1_pombe.fasta]
  • MAD2 (mitotic arrest deficient, homolog)-like 1 [HMR_022704-rand.fasta]
  • Mitotic spindle assembly checkpoint protein MAD2A [ipi.MOUSE.v3.06.fasta]
  • MAD2 (mitotic arrest deficient, homolog)-like 1 [Mus musculus]gi|7769762|gb|AAF69525.1| spindle assembly checkpoint protein [Mus musculus]gi|26350121|dbj|BAC38700.1| unnamed protein product [Mus musculus]gi|12643257|sp|Q9Z1B5|MD21_MOUSE Mitotic spindle [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Mitotic spindle assembly checkpoint protein MAD2A [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • MAD2 (mitotic arrest deficient, homolog)-like 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • mCG125314, isoform CRA_a [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • MAD2 (mitotic arrest deficient, homolog)-like 1 (yeast) [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • spindle assembly checkpoint protein [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • MAD2 mitotic arrest deficient-like 1 [Mus musculus] [NCBI-RefSeq_mouse_na_04-07-2009_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Mad2l1 Mitotic spindle assembly checkpoint protein MAD2A [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Mad2l1 Mitotic spindle assembly checkpoint protein MAD2A ENSMUSG00000029910 IPI00323422 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • mitotic spindle assembly checkpoint protein MAD2A [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00323422.1|SWISS-PROT:Q9Z1B5|TREMBL:Q3TV93;Q5HZH8;Q9D802|ENSEMBL:ENSMUSP00000078504;ENSMUSP00000098897;ENSMUSP00000112304|REFSEQ:NP_062372|VEGA:OTTMUSP00000027373;OTTMUSP00000027374 Tax_Id=10090 Gene_Symbol=Mad2l1 Mitotic spindle assembly checkpoint protein MAD2A [ipi.MOUSE.fasta.20090209]
  • Mitotic spindle assembly checkpoint protein MAD2A OS=Mus musculus GN=Mad2l1 [011711_HMR.fasta]
  • Mitotic spindle assembly checkpoint protein MAD2A OS=Mus musculus GN=Mad2l1 PE=2 SV=2 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta]
  • sp|Q9Z1B5|MD2L1_MOUSE Mitotic spindle assembly checkpoint protein MAD2A OS=Mus musculus GN=Mad2l1 PE=2 SV=2 [uniprot.sptr.mouse.20130102]
  • tr|Q5HZH8|Q5HZH8_MOUSE MAD2 mitotic arrest deficient-like 1 (Yeast) OS=Mus musculus GN=Mad2l1 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • MAD2 mitotic arrest deficient-like 1 (Yeast) OS=Mus musculus GN=Mad2l1 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
  • Isoform of Q9Z1B5, MAD2 mitotic arrest deficient-like 1 (Yeast) OS=Mus musculus GN=Mad2l1 PE=1 SV=1 [MOUSE.fasta.20160308]
    • Organism: Mus musculus
    Length: 205 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQQLAREQG ITLRGSAEIV AEFFSFGINS ILYQRGIYPS ETFTRVQKYG LTLLTTTDPE  60
   61 LIKYLNNVVE QLKEWLYKCS VQKLVVVISN IESGEVLERW QFDIECDKTA KEEGVRREKS 120
  121 QKAIQDEIRS VIRQITATVT FLPLLEVSCS FDLLIYTDKD LVVPEKWEES GPQFITNCEE 180
  181 VRLRSFTTTI HKVNSMVAYK TPVND

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..205] PSI-BLAST 69.69897 The Mad2 spindle checkpoint protein possesses two distinct natively folded states

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.14424444268625 bayes_pls_golite062009
  • protein binding
    		•  0.856075580719879 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.77

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle