Protein Overview: TP2A_MOUSE, TOP2...

General Information:
Name(s) found:	TP2A_MOUSE [Swiss-Prot] TOP2A_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|JS0703 DNA topoisomerase (ATP-hydrolyzing) (EC 5.99.1.3) II - mouse [NCBI NR] gi\|6755849\|ref\|NP_035753.1\| topoisomerase (DNA) II alpha [Mus musculus] [NCBI NR] gi\|267150\|sp\|Q01320.1\|TOP2A_MOUSE RecName: Full=DNA topoisomerase 2-alpha; AltName: Full=DNA topoisomerase II, alpha isozyme [NCBI NR] gi\|220616\|dbj\|BAA02076.1\| DNA topoisomerase II [Mus musculus] [NCBI NR] (Q01320) DNA topoisomerase II, alpha isozyme (EC 5.99.1.3) [Swiss-Prot] DNA topoisomerase 2-alpha OS=Mus musculus GN=Top2a PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):11-99833894 DNA topoisomerase II, alpha isozyme [hmr_yeast5_DM3-1_pombe.fasta] topoisomerase (DNA) II alpha; DNA Topoisomerase II alpha [HMR_022704-rand.fasta] DNA topoisomerase II, alpha isozyme [ipi.MOUSE.v3.06.fasta] topoisomerase (DNA) II alpha [Mus musculus]gi\|90458\|pir\|\|JS0703 DNA topoisomerase (ATP-hydrolyzing) (EC 5.99.1.3) II - mousegi\|220616\|dbj\|BAA02076.1\| DNA topoisomerase II [Mus musculus]gi\|267150\|sp\|Q01320\|TP2A_MOUSE DNA topoisomerase II, alpha isozyme [nrdb_11152004_Chlamydomonas] Tax_Id=10090 DNA topoisomerase 2-alpha [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_011623) topoisomerase (DNA) II alpha; DNA Topoisomerase II alpha [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] topoisomerase (DNA) II alpha [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Tax_Id=10090 DNA topoisomerase II, alpha isozyme [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] DNA topoisomerase 2-alpha (DNA topoisomerase II, alpha isozyme) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] DNA topoisomerase II [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 DNA TOPOISOMERASE II, ALPHA ISOZYME [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Top2a DNA topoisomerase 2-alpha [mouse-ipi-250309-contam.fasta] IPI:IPI00122223.1\|SWISS-PROT:Q01320\|TREMBL:Q3TTG4;Q3UUS6;Q52KI5;Q6PET9;Q8CCE5\|ENSEMBL:ENSMUSP00000068896\|REFSEQ:NP_035753\|VEGA:OTTMUSP00000006845 Tax_Id=10090 Gene_Symbol=Top2a DNA topoisomerase 2-alpha [ipi.MOUSE.fasta.20090209] DNA topoisomerase 2-alpha OS=Mus musculus GN=Top2a [011711_HMR.fasta]
Organism:	Mus musculus
Length:	1528 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELSPLQPVN ENMLMNKKKN EDGKKRLSIE RIYQKKTQLE HILLRPDTYI GSVELVTQQM  60
   61 WVYDEDVGIN YREVTFVPGL YKIFDEILVN AADNKQRDPK MSCIRVTIDP ENNVISIWNN 120
  121 GKGIPVVEHK VEKIYVPALI FGQLLTSSNY DDDEKKVTGG RNGYGAKLCN IFSTKFTVET 180
  181 ASRAYKKMFK QTWMDNMGRA GDMELKPFSG EDYTCITFQP DLSKFKMQSL DKDIVALMVR 240
  241 RAYDIAGSTK DVKVFLNGNM LPVKGFRSYV DLYLKDKVDE TGNSLKVIHE QVNPRWEVCL 300
  301 TMSERGFQQI SFVNSIATSK GGRHVDYVAD QIVSKLVDVV KKKNKGGVAV KAHQVKNHMW 360
  361 IFVNALIENP TFDSQTKENM TLQAKSFGST CQLSEKFIKA AIGCGIVESI LNWVKFKAQI 420
  421 QLNKKCSAVK HTKIKGIPKL DDANDAGSRN STECTLILTE GDSAKTLAVS GLGVVGRDKY 480
  481 GVFPLRGKIL NVREASHKQI MENAEINNII KIVGLQYKKN YEDEDSLKTL RYGKIMIMTD 540
  541 QDQDGSHIKG LLINFIHHNW PSLLRHRFLE EFITPIVKVS KNKQEIAFYS LPEFEEWKSS 600
  601 TPNHKKWKVK YYKGLGTSTS KEAKEYFADM KRHRIQFKYP GPEDDAAISL AFSKKQVDDR 660
  661 KEWLTNFMED RRQRKLLGLP EDYLYGQSTS YLTYNDFINK ELILFSNSDN ERSIPSMVDG 720
  721 LKPGQRKVLF TCFKRNDKRE VKVAQLAGSV AEMSSYHHGE MSLMMTIINL AQNFVGSNNL 780
  781 NLLQPIGQFG TRLHGGKDSA SPRYIFTMLS PLARLLFPPK DDHTLRFLYD DNQRVEPEWY 840
  841 NPINTMVLIN GAEGIGTGWS CKIPNFDVRE VVNNIRRLLD GEEPLPMLPS YKNFKGTIEE 900
  901 LASNQYVING EVAILDSTTI EISELPIRTW TQTYKEQVLE PMLNGTEKTP SLITDYREYH 960
  961 TDTTVKFVIK MTEEKLAEAE RVGLHKVFKL QSSLTCNSMV LFDHVGCLKK YDTVLDILRD1020
 1021 FFELRLKYYG LRKEWLLGML GAESSKLNNQ ARFILEKIDG KIVIENKPKK ELIKVLIQRG1080
 1081 YDSDPVKAWK EAQQKVPDEE ENEESDTETS TSDSAAEAGP TFNYLLDMPL WYLTKEKKDE1140
 1141 LCKQRNEKEQ ELNTLKQKSP SDLWKEDLAV FIEELEVVEA KEKQDEQVGL PGKAGKAKGK1200
 1201 KAQMCADVLP SPRGKRVIPQ VTVEMKAEAE KKIRKKIKSE NVEGTPAEDG AEPGSLRQRI1260
 1261 EKKQKKEPGA KKQTTLPFKP VKKGRKKNPW SDSESDVSSN ESNVDVPPRQ KEQRSRAAKA1320
 1321 KFTVDLDSDE DFSGLDEKDE DEDFLPLDAT PPKAKIPPKN TKKALKTQGS SMSVVDLESD1380
 1381 VKDSVPASPG VPAADFPAET EQSKPSKKTV GVKKTATKSQ SSVSTAGTKK RAAPKGTKSD1440
 1441 SALSARVSEK PAPAKAKNSR KRKPSSSDSS DSDFERAISK GATSKKAKGE EQDFPVDLED1500
 1501 TIAPRAKSDR ARKPIKYLEE SDDDDDLF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: TP2A_MOUSE, TOP2...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: