Protein Overview: SCNNA_MOUSE

General Information:
Name(s) found:	SCNNA_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8928570\|sp\|Q61180.2\|SCNNA_MOUSE RecName: Full=Amiloride-sensitive sodium channel subunit alpha; AltName: Full=Epithelial Na(+) channel subunit alpha; AltName: Full=Alpha-ENaC; AltName: Full=SCNEA; AltName: Full=Nonvoltage-gated sodium channel 1 subunit [NCBI NR] gi\|4469399\|gb\|AAD21244.1\| epithelial sodium channel alpha subunit [Mus musculus] [NCBI NR] gi\|33859618\|ref\|NP_035454.1\| sodium channel, nonvoltage-gated 1 alpha [Mus musculus] [NCBI NR] Amiloride-sensitive sodium channel subunit alpha OS=Mus musculus GN=Scnn1a PE=1 SV=2 [Swiss-Prot] (Q61180) Amiloride-sensitive sodium channel alpha-subunit (Epithelial Na+ channel alpha subunit) (Alpha ENaC) (Nonvoltage-gated sodium channel 1 alpha subunit) (SCNEA) (Alpha NaCH) [Swiss-Prot] Ensembl_locations(Chr-bp):6-126129071 Amiloride-sensitive sodium channel alpha-subunit [hmr_yeast5_DM3-1_pombe.fasta] sodium channel, nonvoltage-gated, type I, alpha polypeptide; ENaC alpha [HMR_022704-rand.fasta] Amiloride-sensitive sodium channel alpha-subunit [ipi.MOUSE.v3.06.fasta] sodium channel, nonvoltage-gated, type I, alpha polypeptide [Mus musculus]gi\|4469399\|gb\|AAD21244.1\| epithelial sodium channel alpha subunit [Mus musculus]gi\|8928570\|sp\|Q61180\|SCAA_MOUSE Amiloride-sensitive sodium channel alpha-subunit (Epithelial Na+ ch [nrdb_11152004_Chlamydomonas] sodium channel, nonvoltage-gated, type I, alpha [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Tax_Id=10090 Amiloride-sensitive sodium channel alpha-subunit [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] sodium channel, nonvoltage-gated 1 alpha [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Amiloride-sensitive sodium channel subunit alpha (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (SCNEA) (Nonvoltage-gated sodium channel 1 subunit alpha) (Alpha-NaCH) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] epithelial sodium channel alpha subunit [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 AMILORIDE-SENSITIVE SODIUM CHANNEL ALPHA-SUBUNIT [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Amiloride-sensitive sodium channel subunit alpha (Epithelial Na+ channel subunit alpha) (Alpha ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA) (Alpha NaCH) [nr-271106-contam.fasta] Amiloride-sensitive sodium channel subunit alpha OS=Mus musculus GN=Scnn1a [122011_mus.fasta] Tax_Id=10090 Gene_Symbol=Scnn1a Amiloride-sensitive sodium channel subunit alpha [EBI-IPI_mouse_2_08-18-2011_reversed.fasta] sp\|Q61180\|SCNNA_MOUSE Amiloride-sensitive sodium channel subunit alpha OS=Mus musculus GN=Scnn1a PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	699 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] sodium channel complex [IGI] membrane [IEA] integral to membrane [IDA] external side of plasma membrane [IDA] apical plasma membrane [UNKNOWN] plasma membrane [IEA] cortical actin cytoskeleton [UNKNOWN]
Biological Process:	sodium ion transport [UNKNOWN][IDA][IGI] ion transport [IEA] sensory perception of taste [IEA] transport [IEA] response to stimulus [IEA]
Molecular Function:	ion channel activity [IEA] actin binding [UNKNOWN] sodium channel activity [IDA] amiloride-sensitive sodium channel activity [UNKNOWN][IDA][IGI] WW domain binding [UNKNOWN][IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDHTRAPEL NLDLDLDVSN SPKGSMKGNN FKEQDLCPPL PMQGLGKGDK REEQALGPEP  60
   61 SEPRQPTEEE EALIEFHRSY RELFQFFCNN TTIHGAIRLV CSKHNRMKTA FWAVLWLCTF 120
  121 GMMYWQFALL FEEYFSYPVS LNINLNSDKL VFPAVTVCTL NPYRYTEIKE DLEELDRITE 180
  181 QTLFDLYKYN SSYTRQAGGR RRSTRDLRGA LPHPLQRLRT PPPPNPARSA RSASSSVRDN 240
  241 NPQVDRKDWK IGFQLCNQNK SDCFYQTYSS GVDAVREWYR FHYINILSRL PDTSPALEEE 300
  301 ALGSFIFTCR FNQAPCNQAN YSQFHHPMYG NCYTFNNKNN SNLWMSSMPG VNNGLSLTLR 360
  361 TEQNDFIPLL STVTGARVMV HGQDEPAFMD DGGFNVRPGV ETSISMRKEA LDSLGGNYGD 420
  421 CTENGSDVPV KNLYPSKYTQ QVCIHSCFQE NMIKKCGCAY IFYPKPKGVE FCDYLKQSSW 480
  481 GYCYYKLQAA FSLDSLGCFS KCRKPCSVTN YKLSAGYSRW PSVKSQDWIF EMLSLQNNYT 540
  541 INNKRNGVAK LNIFFKELNY KTNSESPSVT MVSLLSNLGS QWSLWFGSSV LSVVEMAELI 600
  601 FDLLVITLIM LLHRFRSRYW SPGRGARGAR EVASTPASSF PSRFCPHPTS PPPSLPQQGT 660
  661 TPPLALTAPP PAYATLGPSA SPLDSAVPGS SACAPAMAL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: SCNNA_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: