Protein Overview: SIR2_MOUSE

General Information:
Name(s) found:	SIR2_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|38258618\|sp\|Q8VDQ8.2\|SIRT2_MOUSE RecName: Full=NAD-dependent deacetylase sirtuin-2; AltName: Full=SIR2-like protein 2; Short=mSIR2L2 [NCBI NR] gi\|170650630\|ref\|NP_071877.3\| sirtuin 2 isoform 1 [Mus musculus] [NCBI NR] gi\|148692168\|gb\|EDL24115.1\| sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae), isoform CRA_d [Mus musculus] [NCBI NR] gi\|11612477\|gb\|AAG39256.1\| SIR2L2 [Mus musculus] [NCBI NR] NAD-dependent deacetylase sirtuin-2 OS=Mus musculus GN=Sirt2 PE=1 SV=2 [Swiss-Prot] NAD-dependent protein deacetylase sirtuin-2 OS=Mus musculus GN=Sirt2 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):7-20366132 SIR2L2 [hmr_yeast5_DM3-1_pombe.fasta] Splice Isoform 1 of NAD-dependent deacetylase sirtuin 2 [ipi.MOUSE.v3.06.fasta] NAD-dependent deacetylase sirtuin 2 (SIR2-like protein 2) (mSIR2L2)gi\|11612477\|gb\|AAG39256.1\| SIR2L2 [Mus musculus] [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Splice Isoform 1 of NAD-dependent deacetylase sirtuin-2 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_022432) sirtuin 2 (silent mating type information regulation 2, homolog) 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10090 Splice Isoform 1 of NAD-dependent deacetylase sirtuin 2 [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] NAD-dependent deacetylase sirtuin-2 (SIR2-like protein 2) (mSIR2L2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] sirtuin 2 isoform 1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae), isoform CRA_d [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] SIR2L2 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 SPLICE ISOFORM 1 OF NAD-DEPENDENT DEACETYLASE SIRTUIN 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Sirt2 Isoform 1 of NAD-dependent deacetylase sirtuin-2 [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Sirt2 Isoform 1 of NAD-dependent deacetylase sirtuin-2 ENSMUSG00000015149 IPI00110265 IPI00473688 [IPIxENS.MOUSE_plus_REVERSE.fasta] NAD-dependent deacetylase sirtuin-2 isoform 1 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00110265.1\|SWISS-PROT:Q8VDQ8-1\|ENSEMBL:ENSMUSP00000072732\|REFSEQ:NP_071877\|VEGA:OTTMUSP00000018858 Tax_Id=10090 Gene_Symbol=Sirt2 Isoform 1 of NAD-dependent deacetylase sirtuin-2 [ipi.MOUSE.fasta.20090209] Isoform 1 of NAD-dependent deacetylase sirtuin-2 OS=Mus musculus GN=Sirt2 [011711_HMR.fasta] sp\|Q8VDQ8\|SIR2_MOUSE NAD-dependent protein deacetylase sirtuin-2 OS=Mus musculus GN=Sirt2 PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	389 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEPDPSDPL ETQAGKVQEA QDSDSDTEGG ATGGEAEMDF LRNLFTQTLG LGSQKERLLD  60
   61 ELTLEGVTRY MQSERCRKVI CLVGAGISTS AGIPDFRSPS TGLYANLEKY HLPYPEAIFE 120
  121 ISYFKKHPEP FFALAKELYP GQFKPTICHY FIRLLKEKGL LLRCYTQNID TLERVAGLEP 180
  181 QDLVEAHGTF YTSHCVNTSC RKEYTMGWMK EKIFSEATPR CEQCQSVVKP DIVFFGENLP 240
  241 SRFFSCMQSD FSKVDLLIIM GTSLQVQPFA SLISKAPLAT PRLLINKEKT GQTDPFLGMM 300
  301 MGLGGGMDFD SKKAYRDVAW LGDCDQGCLA LADLLGWKKE LEDLVRREHA NIDAQSGSQA 360
  361 PNPSTTISPG KSPPPAKEAA RTKEKEEQQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.86

Protein Overview: SIR2_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: