Protein Overview: SIR1_MOUSE

General Information:
Name(s) found:	SIR1_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|9790229\|ref\|NP_062786.1\| sirtuin 1 isoform 1 [Mus musculus] [NCBI NR] gi\|6693711\|gb\|AAF24983.1\|AF214646_1 Sir2alpha protein [Mus musculus] [NCBI NR] gi\|38565067\|gb\|AAR23928.1\| Sir2alpha [Mus musculus] [NCBI NR] gi\|38258625\|sp\|Q923E4.2\|SIRT1_MOUSE RecName: Full=NAD-dependent deacetylase sirtuin-1; AltName: Full=SIR2alpha; Short=mSIR2a; Short=Sir2; AltName: Full=SIR2-like protein 1 [NCBI NR] NAD-dependent deacetylase sirtuin-1 OS=Mus musculus GN=Sirt1 PE=1 SV=2 [Swiss-Prot] NAD-dependent protein deacetylase sirtuin-1 OS=Mus musculus GN=Sirt1 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):10-62989072 Sir2alpha protein [hmr_yeast5_DM3-1_pombe.fasta] sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sir2-like 1 [HMR_022704-rand.fasta] NAD-dependent deacetylase sirtuin 1 [ipi.MOUSE.v3.06.fasta] sirtuin 1 ((silent mating type information regulation 2, homolog) 1 [Mus musculus]gi\|38258625\|sp\|Q923E4\|SIR1_MOUSE NAD-dependent deacetylase sirtuin 1 (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1)gi\|6693711\|gb\|AAF24983.1\| Sir2alpha protein [Mus musc [nrdb_11152004_Chlamydomonas] Tax_Id=10090 NAD-dependent deacetylase sirtuin-1 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_019812) sirtuin 1 ((silent mating type information regulation 2, homolog) 1 (S. cerevisiae); sir2-like 1 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] sirtuin 1 ((silent mating type information regulation 2, homolog) 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Tax_Id=10090 NAD-dependent deacetylase sirtuin 1 [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] sirtuin 1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] NAD-dependent deacetylase sirtuin-1 (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Sir2alpha [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Sir2alpha protein [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 NAD-DEPENDENT DEACETYLASE SIRTUIN 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Sirt1 NAD-dependent deacetylase sirtuin-1 [mouse-ipi-250309-contam.fasta] sirtuin 1 isoform 1 [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Sirt1 NAD-dependent deacetylase sirtuin-1 ENSMUSG00000020063 IPI00875167 IPI00134988 [IPIxENS.MOUSE_plus_REVERSE.fasta] NAD-dependent deacetylase sirtuin-1 isoform 1 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00134988.1\|SWISS-PROT:Q923E4\|TREMBL:Q3USJ2;Q53Z05\|ENSEMBL:ENSMUSP00000020257;ENSMUSP00000112595\|REFSEQ:NP_062786\|VEGA:OTTMUSP00000040277 Tax_Id=10090 Gene_Symbol=Sirt1 NAD-dependent deacetylase sirtuin-1 [ipi.MOUSE.fasta.20090209] NAD-dependent deacetylase sirtuin-1 OS=Mus musculus GN=Sirt1 [011711_HMR.fasta] sp\|Q923E4\|SIR1_MOUSE NAD-dependent protein deacetylase sirtuin-1 OS=Mus musculus GN=Sirt1 PE=1 SV=2 [uniprot.sptr.mouse.20130102] tr\|Q53Z05\|Q53Z05_MOUSE Sir2alpha OS=Mus musculus GN=Sirt1 PE=2 SV=1 [uniprot.sptr.mouse.20130102] Sir2alpha OS=Mus musculus GN=Sirt1 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
Organism:	Mus musculus
Length:	737 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADEVALALQ AAGSPSAAAA MEAASQPADE PLRKRPRRDG PGLGRSPGEP SAAVAPAAAG  60
   61 CEAASAAAPA ALWREAAGAA ASAEREAPAT AVAGDGDNGS GLRREPRAAD DFDDDEGEEE 120
  121 DEAAAAAAAA AIGYRDNLLL TDGLLTNGFH SCESDDDDRT SHASSSDWTP RPRIGPYTFV 180
  181 QQHLMIGTDP RTILKDLLPE TIPPPELDDM TLWQIVINIL SEPPKRKKRK DINTIEDAVK 240
  241 LLQECKKIIV LTGAGVSVSC GIPDFRSRDG IYARLAVDFP DLPDPQAMFD IEYFRKDPRP 300
  301 FFKFAKEIYP GQFQPSLCHK FIALSDKEGK LLRNYTQNID TLEQVAGIQR ILQCHGSFAT 360
  361 ASCLICKYKV DCEAVRGDIF NQVVPRCPRC PADEPLAIMK PEIVFFGENL PEQFHRAMKY 420
  421 DKDEVDLLIV IGSSLKVRPV ALIPSSIPHE VPQILINREP LPHLHFDVEL LGDCDVIINE 480
  481 LCHRLGGEYA KLCCNPVKLS EITEKPPRPQ KELVHLSELP PTPLHISEDS SSPERTVPQD 540
  541 SSVIATLVDQ ATNNNVNDLE VSESSCVEEK PQEVQTSRNV ENINVENPDF KAVGSSTADK 600
  601 NERTSVAETV RKCWPNRLAK EQISKRLEGN QYLFVPPNRY IFHGAEVYSD SEDDVLSSSS 660
  661 CGSNSDSGTC QSPSLEEPLE DESEIEEFYN GLEDDTERPE CAGGSGFGAD GGDQEVVNEA 720
  721 IATRQELTDV NYPSDKS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: SIR1_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: