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Protein Overview: CE39682

General Information:
Name(s) found: CE39682 [WormBase]
Description(s) found:
Found 12 descriptions.
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  • WBGene00016335 locus:gba-1 Putative glucosylceramidase 1 status:Confirmed UniProt:O16580 protein_id:CCD66450.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 470 amino acids

    Gene Ontology:
    Cellular Component: lysosome [IEALink to PubMed article]
    Biological Process: lysosome organization [IEALink to PubMed article]
    sphingolipid metabolic process [IEALink to PubMed article]
    Molecular Function: glucosylceramidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQAALYTTS HTGARLHRDV IYATDTEPFG TLHMTIDSSK KYQTIQGFGS TFSDASGANL  60
   61 KSLPDKLSDL IMKQYFSDTG LNLQFGRVPI ASTDFSGRVY SYNDVANDYS MQNFNLTKED 120
  121 FQWKIPYIKN AQKYNPNLKL FAAPWAAPGW LKTTKEMTGP GALNGKAGDN YHQAYAKYFV 180
  181 RFLEEYGKSG ISFWGLSTQN QPTLGSDKKN KIQSTLFTAE TQRDFIKTDL GPALAASSSG 240
  241 KDVKLLILDD NRGNLPKWAD TVLNDMDAAK YVGGIGVHAY QDGETDNHLD ETHKKHPNFF 300
  301 ILGTEASEGY GSKDTHVDYG NWDRAADTAS DILDNMNNWM TGWTERNLIL DALGGPSWVS 360
  361 DYTDAPVIAF PAMAQFYKQP MFYAIAHFSH FIKPGAVRID HSLNVIELEV ETTAFLNPDG 420
  421 SKVIVMLNKG SLVSTEHTVV VQDAADSRNH YHFTLPHRAI TTLYIQTSQF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..470] PSI-BLAST 141.0 No description for 2v3dA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  4.11319792356479 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  3.92012282533754 bayes_pls_golite062009
  • chitinase activity
    		•  2.45357334610104 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • hydrolase activity
    		•  1.54366929433155 bayes_pls_golite062009
  • amylase activity
    		•  0.748967897302847 bayes_pls_golite062009
  • glucosidase activity
    		•  0.528679164808812 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.4998423581103 bayes_pls_golite062009
  • hexosaminidase activity
    		•  0.423006654245821 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle