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Protein Overview: Mhcl-PF

General Information:
Name(s) found: Mhcl-PF / FBpp0110273 [FlyBase]
Description(s) found:
Found 16 descriptions.
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  • The gene Myosin heavy chain-like is referred to in FlyBase by the symbol Dmel\Mhcl (CG31045, FBgn0026059). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11894245..11923310. It has the cytological map location 89B2-89B3. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotypes of these alleles are annotated with: ventral nerve cord; peripheral nervous system. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1923 amino acids

    Gene Ontology:
    Cellular Component: myosin complex [ISS]
    Biological Process: NONE FOUND
    Molecular Function: ATP binding [IEA]
    protein binding [IEA]
    ATPase activity, coupled [ISS]
    motor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLKPKSFEQ SLRGGIVPAV PAAPGSGLNP NFHKGCTGKA HACGTNKSHR AGGSATSASG  60
   61 GSRAGRQTPK AQRKNSISSE TISESGSENS NSWPSSSSAA VPATVPPPKP PRLAATKAKE 120
  121 AAAIDCSPVQ PPFTPTFERS TKRSLSFRSN NSKTTEAKLT PGASSSIRPP WNISAAAASK 180
  181 YAAAAASAPQ SPNPSTRSSF RRRRDAQNAG LHWPAILASS LAASHKNYDA ILKQKSRHEN 240
  241 GNGGGEEGGA KGVGHDLEAD VADASQPERV WLVHRGGFTA AIRLPTASSG RDEENKLSLR 300
  301 LLHNGEQLTV DEDDVEKQNS PALDLVEDIC ELKYLNEASV LHCLRQRYAS NLIHTKAGPT 360
  361 LLVVNPMAPL SLYSEKVVSM FRGCKTEDMP PHVYSLAQTA YRSLVETRRD QSLIFMGRSG 420
  421 SGKSTSFKHA LNYLALAAGA YNNFINAEKV NALCTILEAF GNTKTCLNSN ATRMTQLLSL 480
  481 DFDQTGQIAS ASLQVLLPER QRAGRRLGHE HSFHIMTRLL AGAAGLLQKE LHLENITSED 540
  541 SHPFISLSQK LEDRHRAAND FMRTVQAFET LNIDAKAVRG IWSILAAIYH LGIAGVTKLG 600
  601 TGSTARTQFA NPTAARKASG LLGVNLEDLS SAAFGLTQPN APNGGLSPSK SPTSDTGHEW 660
  661 AWECLEALVI GLYSEALAAV VALINRQICT SSHTIASIML IDTPGFQNPA SCGQQVGATL 720
  721 ADLRHNYLQE RLQMLFHHTT LVAPRDRYAQ ELVEIEMDLA SECHPGPLIS LIDKAPQNHV 780
  781 VRSSQRDLRE HDRRGMLWLL DEEAIYPNSN DDTFLERLFS HYGDREHHSL LRKCAGPRQF 840
  841 VLHHLQGTNP VLYAVDGWVR HSREHPGIRN AVSLLQDSSR EEINRLYIGS LTRGSGAMVF 900
  901 CGSFAGLEGT QSLRRVSSIR RSFTTAGVKR NSIMLQVKFT VDGIIDTLRR TGTHFVHCYL 960
  961 LQHNAGKHTK YTANGSPSSA AGQVSSEEEM VNVPLLRSQL RGSQVLEAAR LHRLGFPESV1020
 1021 PLLEFVRRFG LLAGDLASNK DVSVEQILAV NELDVASYRI GPSQILFRSG VLSELEAKRD1080
 1081 VLLSDRIIQL QAFCRGYLAR KKMSQRRVQE LAVRCIQRNV KAFLAVRDWP WWRLLVRVTP1140
 1141 LLNVHRTEEQ LKTANEELLM LRAKLEKIEC DRSEVKAENQ KLEAKLSELT VDLAEERSTA1200
 1201 HIATERLEAE TAERLKLEKE LGDQTNKVKN LQETTEKLEM ELICAKSDLN GISEDEDAEN1260
 1261 EDGVGGGVYK LKYERVAREL EFTKRRLHTQ HEHDLEQLVA LKKHLEMKLS DAYEEVVEQR1320
 1321 QVVGQWKRKA QKMTNEMNDL RMLLEEQNAR NNLLEKKQRK FDAECQSLQD AVRQERQAKE1380
 1381 RYGREKDVLQ AEKFTLEQTL ADTRLDLEFK EEKLASLQRE LEEMTFGGGT EEEFAQLRRS1440
 1441 KNETERRAKE QEEELDEMAG QIQLLEQAKL RLEMTLETMR KEARRESQQR DEELEEVRGN1500
 1501 GYKKIKALEC QLETEHEERT LLLREKHELE RRLSSMEDRD RVDRDAEEAL NQKLRRDLRK1560
 1561 YKALLKDAQT QLERLKADTP GKTLIRQLRN QLEDAESARS LAMKARQTAE AELTEVQAMF1620
 1621 DESHRARNDA EERANAAHRD RAELQAQIEE NEEELGELMK KYSATVKQLN TEQINVSEAE1680
 1681 FKLNEMEAER NNLKEQVAEL QHRLDNVENL GDPSMAMMSK RLELRTKELE SRLELEQATR1740
 1741 ARLEVQVNRH KEALEKLQNE VTQSKMREMQ AQDVIKKSQK SLRDMREEFH AVSSREQESL1800
 1801 TRRKDLEKKV EQMESEGAAL KNDLRLALQR IADLQQAMEE EGEEELSESD ESLSSVGSIS1860
 1861 DLEDRLRPVH VKRSSQQSLN GSIGGGGGSV VSSTRTVVFE KDDNSPRYAD NEVNSNSRKQ1920
 1921 HKH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..249] PSI-BLAST 17.69897 No description for 1y0fA was found.
    2 View Details [250..1464] PSI-BLAST 1000.0 Heavy meromyosin subfragment
    3 View Details [1465..1610] FFAS03 1.56 Fibrinogen C-terminal domains; Fibrinogen gamma chain
    4 View Details [1611..1923] PSI-BLAST 4.09691 No description for 2ch7B was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.70

    Source: Reynolds et al. (2008)

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