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Protein Overview: Mhcl-PG

General Information:
Name(s) found: Mhcl-PG / FBpp0110274 [FlyBase]
Description(s) found:
Found 16 descriptions.
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  • The gene Myosin heavy chain-like is referred to in FlyBase by the symbol Dmel\Mhcl (CG31045, FBgn0026059). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11894245..11923310. It has the cytological map location 89B2-89B3. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotypes of these alleles are annotated with: ventral nerve cord; peripheral nervous system. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 2160 amino acids

    Gene Ontology:
    Cellular Component: myosin complex [ISS]
    Biological Process: NONE FOUND
    Molecular Function: ATP binding [IEA]
    protein binding [IEA]
    ATPase activity, coupled [ISS]
    motor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFNFMKKSAG DEDKERRKRE KKLRKEAKGT SGGPGMGGVT GVTGSMSTDE LLRLDEVRRS  60
   61 LKIRGRRKEK EKLPSGITAD YSADFFAALN ADANGGSNGG AVGAADPEQD RGNEEIVASV 120
  121 MTHIESRASN GAGVSVNYSE VTHSLLSGGL KNRFLPPIPP KPPKRGILKG SRSNMTNVHE 180
  181 EISFAGSAGG AGGTPEMLLR NTFQNESLYE GAARGAGSIG SNSSQHGTSF TSVESLRSDG 240
  241 EQTGGQQRAM TLPANARYGA LPQGNSQGSH LHVLTSPSPS ADSLTDTTNS SFATPPFSLS 300
  301 PVGESQGIDR WARVHAFEDV ELPLPPVQLV KLPPPRQLVI RRQKSPRQDF GFSLRKAICL 360
  361 DRTESLTSPI FRPVIFAEPG AGGGATGLLP GDRLIKVNGT PVGELPREII IEMIRNSGEA 420
  421 VTVEVQPVAE LVELSKRCMA PSTATVEEID HSITNGNCNT LRRSASKRFK RQSRHENGNG 480
  481 GGEEGGAKGV GHDLEADVAD ASQPERVWLV HRGGFTAAIR LPTASSGRDE ENKLSLRLLH 540
  541 NGEQLTVDED DVEKQNSPAL DLVEDICELK YLNEASVLHC LRQRYASNLI HTKAGPTLLV 600
  601 VNPMAPLSLY SEKVVSMFRG CKTEDMPPHV YSLAQTAYRS LVETRRDQSL IFMGRSGSGK 660
  661 STSFKHALNY LALAAGAYNN FINAEKVNAL CTILEAFGNT KTCLNSNATR MTQLLSLDFD 720
  721 QTGQIASASL QVLLPERQRA GRRLGHEHSF HIMTRLLAGA AGLLQKELHL ENITSEDSHP 780
  781 FISLSQKLED RHRAANDFMR TVQAFETLNI DAKAVRGIWS ILAAIYHLGI AGVTKLGTGS 840
  841 TARTQFANPT AARKASGLLG VNLEDLSSAA FGLTQPNAPN GGLSPSKSPT SDTGHEWAWE 900
  901 CLEALVIGLY SEALAAVVAL INRQICTSSH TIASIMLIDT PGFQNPASCG QQVGATLADL 960
  961 RHNYLQERLQ MLFHHTTLVA PRDRYAQELV EIEMDLASEC HPGPLISLID KAPQNHVVRS1020
 1021 SQRDLREHDR RGMLWLLDEE AIYPNSNDDT FLERLFSHYG DREHHSLLRK CAGPRQFVLH1080
 1081 HLQGTNPVLY AVDGWVRHSR EHPGIRNAVS LLQDSSREEI NRLYIGSLTR GSGAMVFCGS1140
 1141 FAGLEGTQSL RRVSSIRRSF TTAGVKRNSI MLQVKFTVDG IIDTLRRTGT HFVHCYLLQH1200
 1201 NAGKHTKYTA NGSPSSAAGQ VSSEEEMVNV PLLRSQLRGS QVLEAARLHR LGFPESVPLL1260
 1261 EFVRRFGLLA GDLASNKDVS VEQILAVNEL DVASYRIGPS QILFRSGVLS ELEAKRDVLL1320
 1321 SDRIIQLQAF CRGYLARKKM SQRRVQELAV RCIQRNVKAF LAVRDWPWWR LLVRVTPLLN1380
 1381 VHRTEEQLKT ANEELLMLRA KLEKIECDRS EVKAENQKLE AKLSELTVDL AEERSTAHIA1440
 1441 TERLEAETAE RLKLEKELGD QTNKVKNLQE TTEKLEMELI CAKSDLNGIS EDEDAENEDG1500
 1501 VGGGVYKLKY ERVARELEFT KRRLHTQHEH DLEQLVALKK HLEMKLSDAY EEVVEQRQVV1560
 1561 GQWKRKAQKM TNEMNDLRML LEEQNARNNL LEKKQRKFDA ECQSLQDAVR QERQAKERYG1620
 1621 REKDVLQAEK FTLEQTLADT RLDLEFKEEK LASLQRELEE MTFGGGTEEE FAQLRRSKNE1680
 1681 TERRAKEQEE ELDEMAGQIQ LLEQAKLRLE MTLETMRKEA RRESQQRDEE LEEVRGNGYK1740
 1741 KIKALECQLE TEHEERTLLL REKHELERRL SSMEDRDRVD RDAEEALNQK LRRDLRKYKA1800
 1801 LLKDAQTQLE RLKADTPGKT LIRQLRNQLE DAESARSLAM KARQTAEAEL TEVQAMFDES1860
 1861 HRARNDAEER ANAAHRDRAE LQAQIEENEE ELGELMKKYS ATVKQLNTEQ INVSEAEFKL1920
 1921 NEMEAERNNL KEQVAELQHR LDNVENLGDP SMAMMSKRLE LRTKELESRL ELEQATRARL1980
 1981 EVQVNRHKEA LEKLQNEVTQ SKMREMQAQD VIKKSQKSLR DMREEFHAVS SREQESLTRR2040
 2041 KDLEKKVEQM ESEGAALKND LRLALQRIAD LQQAMEEEGE EELSESDESL SSVGSISDLE2100
 2101 DRLRPVHVKR SSQQSLNGSI GGGGGSVVSS TRTVVFEKDD NSPRYADNEV NSNSRKQHKH2160
 2161

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..488] PSI-BLAST 16.30103 No description for 1y0fB was found.
    2 View Details [489..1705] PSI-BLAST 1000.0 Heavy meromyosin subfragment
    3 View Details [1706..1893] FFAS03 2.1 Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
    4 View Details [1894..2160] PSI-BLAST 15.39794 Tropomyosin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle