YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: DYRK3

General Information:
Name(s) found: DYRK3 [HGNC (HUGO)]
Description(s) found:
Found 30 descriptions.
SHOW ALL
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 588 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGTARGPGR KDAGPPGAGL PPQQRRLGDG VYDTFMMIDE TKCPPCSNVL CNPSEPPPPR  60
   61 RLNMTTEQFT GDHTQHFLDG GEMKVEQLFQ EFGNRKSNTI QSDGISDSEK CSPTVSQGKS 120
  121 SDCLNTVKSN SSSKAPKVVP LTPEQALKQY KHHLTAYEKL EIINYPEIYF VGPNAKKRHG 180
  181 VIGGPNNGGY DDADGAYIHV PRDHLAYRYE VLKIIGKGSF GQVARVYDHK LRQYVALKMV 240
  241 RNEKRFHRQA AEEIRILEHL KKQDKTGSMN VIHMLESFTF RNHVCMAFEL LSIDLYELIK 300
  301 KNKFQGFSVQ LVRKFAQSIL QSLDALHKNK IIHCDLKPEN ILLKHHGRSS TKVIDFGSSC 360
  361 FEYQKLYTYI QSRFYRAPEI ILGSRYSTPI DIWSFGCILA ELLTGQPLFP GEDEGDQLAC 420
  421 MMELLGMPPP KLLEQSKRAK YFINSKGIPR YCSVTTQADG RVVLVGGRSR RGKKRGPPGS 480
  481 KDWGTALKGC DDYLFIEFLK RCLHWDPSAR LTPAQALRHP WISKSVPRPL TTIDKVSGKR 540
  541 VVNPASAFQG LGSKLPPVVG IANKLKANLM SETNGSIPLC SVLPKLIS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..140] FFAS03 0.982 Riboflavin kinase
    2 View Details [141..195] PSI-BLAST 47.30103 No description for 2j0jA was found.
    3 View Details [196..522] PSI-BLAST 49.09691 Crystal structure of human CLK1 in complex with 10Z-Hymenialdisine
    4 View Details [523..588] PSI-BLAST 55.0 crystal structure of Glycogen synthase kinase 3 in complexed with inhibitor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleotidyltransferase activity
    		•  5.59376023091234 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.18423339044378 bayes_pls_golite062009
  • kinase activity
    		•  5.0294488232015 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.70542899771579 bayes_pls_golite062009
  • transferase activity
    		•  3.88612105627624 bayes_pls_golite062009
  • binding
    		•  1.90127159993102 bayes_pls_golite062009
  • catalytic activity
    		•  1.869789701891 bayes_pls_golite062009
  • protein binding
    		•  1.4526641351614 bayes_pls_golite062009
  • riboflavin kinase activity
    		•  1.30775390950083 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle