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Protein Overview: LIN7B

General Information:
Name(s) found: LIN7B [HGNC (HUGO)]
Description(s) found:
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  • gi|59798472|sp|Q9HAP6.1|LIN7B_HUMAN RecName: Full=Lin-7 homolog B; Short=Lin-7B; Short=hLin7B; AltName: Full=Mammalian lin-seven protein 2; Short=MALS-2; AltName: Full=Vertebrate lin-7 homolog 2; Short=Veli-2 protein; Short=hVeli2 [NCBI NR]
  • gi|37182607|gb|AAQ89104.1| LIN-7B [Homo sapiens] [NCBI NR]
  • gi|20381193|gb|AAH27618.1| Lin-7 homolog B (C. elegans) [Homo sapiens] [NCBI NR]
  • gi|119572840|gb|EAW52455.1| lin-7 homolog B (C. elegans), isoform CRA_b [Homo sapiens] [NCBI NR]
  • gi|11545920|ref|NP_071448.1| lin-7 homolog B [Homo sapiens] [NCBI NR]
  • gi|11321325|gb|AAG34117.1|AF311862_1 Lin-7b [Homo sapiens] [NCBI NR]
  • lin-7 homolog B (C. elegans) [HGNC (HUGO)]
  • Protein lin-7 homolog B OS=Homo sapiens GN=LIN7B PE=1 SV=1 [Swiss-Prot]
  • Lin-7b protein, likely ortholog of mouse LIN-7B, mammalian LIN-7 protein 2 [hmr_yeast5_DM3-1_pombe.fasta]
  • lin-7 homolog B; Lin-7b protein; likely ortholog of mouse LIN-7B; mammalian LIN-7 protein 2 [HMR_022704.fasta]
  • LIN-7B [Homo sapiens]gi|11545920|ref|NP_071448.1| lin-7 homolog B [Homo sapiens]gi|20381193|gb|AAH27618.1| Lin-7 homolog B [Homo sapiens]gi|11321325|gb|AAG34117.1| Lin-7b [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • LIN-7 homolog B (LIN-7B) (hLin7B) (Mammalian LIN-seven protein 2) (MALS-2) (Vertebrate LIN 7 homolog 2) (Veli-2 protein) (hVeli2) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 LIN-7 homolog B [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_022165) Lin-7b protein [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • lin-7 homolog B [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • lin-7 homolog B; Lin-7b protein; likely ortholog of mouse LIN-7B; mammalian LIN-7 protein 2 [Homo sapiens] [HumanGallus06162005.fasta]
  • Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • lin-7 homolog B (C. elegans), isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Lin-7 homolog B (C. elegans) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • LIN-7B [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Lin-7b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Lin-7 homolog B [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 LIN-7B [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=LIN7B Lin-7 homolog B [human-ipi-250309-contam.fasta]
  • IPI:IPI00005566.1|SWISS-PROT:Q9HAP6|ENSEMBL:ENSP00000221459|REFSEQ:NP_071448|H-INV:HIT000252788|VEGA:OTTHUMP00000077215;OTTHUMP00000165836 Tax_Id=9606 Gene_Symbol=LIN7B Lin-7 homolog B [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=LIN7B Lin-7 homolog B ENSG00000104863 IPI00005566 IPI00792650 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=LIN7B Protein lin-7 homolog B [EBI-IPI_Human_3.71_03-24-2010_reversed.fasta]
  • protein lin-7 homolog B [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q9HAP6; RecName: Full=Protein lin-7 homolog B; AltName: Full=Mammalian lin-seven protein 2; AltName: Full=Vertebrate lin-7 homolog 2; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Protein lin-7 homolog B OS=Homo sapiens GN=LIN7B [011711_HMR.fasta]
  • IPI:IPI00005566.1|SWISS-PROT:Q9HAP6|ENSEMBL:ENSP00000221459|REFSEQ:NP_071448|H-INV:HIT000252788|VEGA:OTTHUMP00000077215;OTTHUMP00000165836 Tax_Id=9606 Gene_Symbol=LIN7B Protein lin-7 homolog B [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=LIN7B Synonyms=LIN-7B|MALS-2|MALS2|VELI2 protein lin-7 homolog B [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00005566.1|SWISS-PROT:Q9HAP6|ENSEMBL:ENSP00000221459|REFSEQ:NP_071448|H-INV:HIT000252788|VEGA:OTTHUMP00000165836 Tax_Id=9606 Gene_Symbol=LIN7B Protein lin-7 homolog B [ipi.HUMAN.20110912.fasta]
  • Protein lin-7 homolog B GN=LIN7B [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 207 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALVEPLGL ERDVSRAVEL LERLQRSGEL PPQKLQALQR VLQSRFCSAI REVYEQLYDT  60
   61 LDITGSAEIR AHATAKATVA AFTASEGHAH PRVVELPKTD EGLGFNIMGG KEQNSPIYIS 120
  121 RVIPGGVADR HGGLKRGDQL LSVNGVSVEG EQHEKAVELL KAAQGSVKLV VRYTPRVLEE 180
  181 MEARFEKMRS ARRRQQHQSY SSLESRG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] FFAS03 4.44 Solution Structure of mLin-2/mLin-7 L27 Domain Complex
    2 View Details [89..207] PSI-BLAST 20.69897 No description for 2dkrA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • epidermal growth factor receptor binding
    		•  2.83728577240611 bayes_pls_golite062009
  • binding
    		•  1.72922707266313 bayes_pls_golite062009
  • protein binding
    		•  1.08813585723961 bayes_pls_golite062009
  • PDZ domain binding
    		•  0.950044269901752 bayes_pls_golite062009
  • receptor binding
    		•  0.684990774885903 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.450006870427269 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle