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Protein Overview: FGF4

General Information:
Name(s) found: FGF4 [HGNC (HUGO)]
Description(s) found:
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  • pir||TVHUHS fibroblast growth factor 4 - human [NCBI NR]
  • gi|4503701|ref|NP_001998.1| fibroblast growth factor 4 precursor [Homo sapiens] [NCBI NR]
  • gi|386788|gb|AAB59555.1| transforming protein [Homo sapiens] [NCBI NR]
  • gi|307092|gb|AAA59473.1| fibroblast growth factor (put.); putative [Homo sapiens] [NCBI NR]
  • gi|245437|gb|AAB21430.1| HST1=fibroblast growth factor related protein [human, stomach, Peptide, 206 aa] [NCBI NR]
  • gi|122750|sp|P08620.1|FGF4_HUMAN RecName: Full=Fibroblast growth factor 4; Short=FGF-4; AltName: Full=Heparin secretory-transforming protein; AltName: Full=HST-1; Short=HST; AltName: Full=Transforming protein KS3; AltName: Full=Heparin-binding growth fact [NCBI NR]
  • gi|119595158|gb|EAW74752.1| fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene) [Homo sapiens] [NCBI NR]
  • fibroblast growth factor 4 [HGNC (HUGO)]
  • Fibroblast growth factor 4 OS=Homo sapiens GN=FGF4 PE=1 SV=1 [Swiss-Prot]
  • Fibroblast growth factor-4 precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • fibroblast growth factor 4 precursor; heparin secretory transforming protein 1; oncogene HST; human stomach cancer, transforming factor from FGF-related oncogene; kaposi sarcoma oncogene; transforming protein KS3 [HMR_022704.fasta]
  • fibroblast growth factor 4 precursor [Homo sapiens]gi|69033|pir||TVHUHS fibroblast growth factor 4 - humangi|386788|gb|AAB59555.1| transforming protein [Homo sapiens]gi|245437|gb|AAB21430.1| HST1=fibroblast growth factor related protein [human, stomach [nrdb_11152004_Chlamydomonas]
  • Fibroblast growth factor 4 precursor (FGF-4) (Heparin secretory transforming protein) (HST-1) (HST) (Transforming protein KS3) (HBGF-4) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Fibroblast growth factor 4 precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_002007) fibroblast growth factor 4 precursor; heparin secretory transforming protein 1; oncogene HST; human stomach cancer, transforming factor from FGF-related oncogene; kaposi sarcoma oncogene; transforming protein KS3 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • fibroblast growth factor 4 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Fibroblast growth factor-4 precursor [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • fibroblast growth factor 4 precursor; heparin secretory transforming protein 1; oncogene HST; human stomach cancer, transforming factor from FGF-related oncogene; kaposi sarcoma oncogene; transforming protein KS3 [Homo sapiens] [HumanGallus06162005.fasta]
  • Fibroblast growth factor 4 precursor (FGF-4) (Heparin secretory-transforming protein) (HST-1) (HST) (Transforming protein KS3) (HBGF-4) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • HST1=fibroblast growth factor related protein [human, stomach, Peptide, 206 aa] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • transforming protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • fibroblast growth factor (put.); putative [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 FIBROBLAST GROWTH FACTOR-4 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=FGF4 Fibroblast growth factor 4 [human-ipi-250309-contam.fasta]
  • IPI:IPI00029760.1|SWISS-PROT:P08620|TREMBL:B7U994|ENSEMBL:ENSP00000168712|REFSEQ:NP_001998|H-INV:HIT000194544 Tax_Id=9606 Gene_Symbol=FGF4 Fibroblast growth factor 4 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=FGF4 Fibroblast growth factor 4 precursor ENSG00000075388 IPI00029760 IPI00028232 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=FGF4 Fibroblast growth factor 4 precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • P08620; RecName: Full=Fibroblast growth factor 4; AltName: Full=Heparin secretory-transforming protein 1; AltName: Full=Transforming protein KS3; AltName: Full=Heparin-binding growth factor 4; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Fibroblast growth factor 4 OS=Homo sapiens GN=FGF4 [011711_HMR.fasta]
  • GeneSymbol=FGF4 Synonyms=HBGF-4|HST|HST-1|HSTF1|K-FGF|KFGF fibroblast growth factor 4 precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00029760.1|SWISS-PROT:P08620|TREMBL:B7U994|ENSEMBL:ENSP00000168712|REFSEQ:NP_001998|H-INV:HIT000194544|VEGA:OTTHUMP00000237541 Tax_Id=9606 Gene_Symbol=FGF4 Fibroblast growth factor 4 [ipi.HUMAN.20110912.fasta]
  • Fibroblast growth factor 4 GN=FGF4 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 206 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGPGTAAVA LLPAVLLALL APWAGRGGAA APTAPNGTLE AELERRWESL VALSLARLPV  60
   61 AAQPKEAAVQ SGAGDYLLGI KRLRRLYCNV GIGFHLQALP DGRIGGAHAD TRDSLLELSP 120
  121 VERGVVSIFG VASRFFVAMS SKGKLYGSPF FTDECTFKEI LLPNNYNAYE SYKYPGMFIA 180
  181 LSKNGKTKKG NRVSPTMKVT HFLPRL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..206] PSI-BLAST 42.522879 Fibroblast growth factor 4 (FGF4)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • fibroblast growth factor receptor binding
    		•  5.68976822724664 bayes_pls_golite062009
  • growth factor activity
    		•  5.6790632853895 bayes_pls_golite062009
  • receptor binding
    		•  4.8109037277027 bayes_pls_golite062009
  • cytokine activity
    		•  3.72907359340826 bayes_pls_golite062009
  • protein binding
    		•  2.99442649109752 bayes_pls_golite062009
  • binding
    		•  2.90110516688922 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  2.49177421879896 bayes_pls_golite062009
  • heparin binding
    		•  2.1616134585534 bayes_pls_golite062009
  • polysaccharide binding
    		•  1.81686028727894 bayes_pls_golite062009
  • signal transducer activity
    		•  1.24692031673405 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.24692031673405 bayes_pls_golite062009
  • interleukin-1 receptor binding
    		•  0.8084616632765 bayes_pls_golite062009
  • pattern binding
    		•  0.323275442862789 bayes_pls_golite062009
  • nerve growth factor receptor binding
    		•  0.308245352535379 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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