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Protein Overview: INS

General Information:
Name(s) found: INS [HGNC (HUGO)]
Description(s) found:
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  • gi|758088|emb|CAA23828.1| preproinsulin [Homo sapiens] [NCBI NR]
  • pir||IPHU insulin precursor [validated] - human [NCBI NR]
  • gi|59036749|gb|AAW83741.1| proinsulin [Homo sapiens] [NCBI NR]
  • gi|4557671|ref|NP_000198.1| proinsulin precursor [Homo sapiens] [NCBI NR]
  • gi|394766|emb|CAA49913.1| pre-proinsulin [Homo sapiens] [NCBI NR]
  • gi|386829|gb|AAA59173.1| insulin [Homo sapiens] [NCBI NR]
  • gi|386828|gb|AAA59172.1| insulin [Homo sapiens] [NCBI NR]
  • gi|30582455|gb|AAP35454.1| insulin [Homo sapiens] [NCBI NR]
  • gi|23986711|gb|AAN39451.1| insulin [Homo sapiens] [NCBI NR]
  • gi|223160|prf||0601246A insulin,prepro [NCBI NR]
  • gi|13528924|gb|AAH05255.1| Insulin [Homo sapiens] [NCBI NR]
  • gi|124617|sp|P01308.1|INS_HUMAN RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor [NCBI NR]
  • gi|119622894|gb|EAX02489.1| insulin, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119622893|gb|EAX02488.1| insulin, isoform CRA_a [Homo sapiens] [NCBI NR]
  • insulin [HGNC (HUGO)]
  • Insulin OS=Homo sapiens GN=INS PE=1 SV=1 [Swiss-Prot]
  • Insulin precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • proinsulin precursor [HMR_022704.fasta]
  • insulin [Homo sapiens]gi|22901140|gb|AAN06935.1| insulin precursor [Gorilla gorilla]gi|4557671|ref|NP_000198.1| proinsulin precursor [Homo sapiens]gi|30582455|gb|AAP35454.1| insulin [Homo sapiens]gi|13528924|gb|AAH05255.1| Proinsulin, precursor [Homo [nrdb_11152004_Chlamydomonas]
  • Insulin precursor [Contains: Insulin B chain; Insulin A chain] [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Insulin precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_000207) proinsulin precursor [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • proinsulin precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • insulin, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Insulin [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • proinsulin [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • insulin [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • pre-proinsulin [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • insulin,prepro [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • preproinsulin [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 INSULIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=INS Insulin [human-ipi-250309-contam.fasta]
  • IPI:IPI00001508.1|SWISS-PROT:P01308|ENSEMBL:ENSP00000250971;ENSP00000370731;ENSP00000380432|REFSEQ:NP_000198|VEGA:OTTHUMP00000011161;OTTHUMP00000011162;OTTHUMP00000196038 Tax_Id=9606 Gene_Symbol=INS-IGF2;INS Insulin [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=INS Insulin precursor ENSG00000129965 IPI00853225 IPI00001508 IPI00853573 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=INS Insulin precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=INS;INS-IGF2 Insulin [EBI-IPI_Human_3.71_03-24-2010_reversed.fasta]
  • P01308;Q5EEX2; RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Insulin OS=Homo sapiens GN=INS [011711_HMR.fasta]
  • IPI:IPI00001508.1|SWISS-PROT:P01308|ENSEMBL:ENSP00000250971;ENSP00000370731;ENSP00000380432|REFSEQ:NP_000198|VEGA:OTTHUMP00000011161;OTTHUMP00000011162;OTTHUMP00000196038 Tax_Id=9606 Gene_Symbol=INS;INS-IGF2 Insulin [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=INS Synonyms=IDDM2|ILPR|IRDN|MODY10 insulin preproprotein [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00001508.1|SWISS-PROT:P01308|TREMBL:F6MZK5|ENSEMBL:ENSP00000250971;ENSP00000370731;ENSP00000380432|REFSEQ:NP_000198;NP_001172026;NP_001172027|VEGA:OTTHUMP00000011161;OTTHUMP00000011162;OTTHUMP00000196038 Tax_Id=9606 Gene_Symbol=INS;IGF2;INS-IGF2 Insulin [ipi.HUMAN.20110912.fasta]
  • Insulin GN=INS [Doctor+uniprot-HUMAN-120911.fasta]
  • Tax_Id=9606 Gene_Symbol=IGF2;INS;INS-IGF2 Insulin [human-ipi-270911-contam-BSA.fasta]
  • IPI:IPI00001508.1|SWISS-PROT:P01308|TREMBL:F6MZK5|ENSEMBL:ENSP00000250971;ENSP00000370731;ENSP00000380432|REFSEQ:NP_000198;NP_001172026;NP_001172027|VEGA:OTTHUMP00000011161;OTTHUMP00000011162;OTTHUMP00000196038 Tax_Id=9606 Gene_Symbol=IGF2;INS;INS-IGF2 Insulin [ipi.HUMAN.fasta.20110927]
  • Insulin, isoform CRA_a OS=Homo sapiens GN=INS PE=2 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 110 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALWMRLLPL LALLALWGPD PAAAFVNQHL CGSHLVEALY LVCGERGFFY TPKTRREAED  60
   61 LQVGQVELGG GPGAGSLQPL ALEGSLQKRG IVEQCCTSIC SLYQLENYCN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..110] PSI-BLAST 17.69897 Insulin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.278956919805523 bayes_pls_golite062009
  • protein binding
    		•  0.06220495723124 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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