Protein Overview: ATP8A1

General Information:
Name(s) found:	ATP8A1 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|8134331\|sp\|Q9Y2Q0.1\|AT8A1_HUMAN RecName: Full=Probable phospholipid-transporting ATPase IA; AltName: Full=Chromaffin granule ATPase II; AltName: Full=ATPase class I type 8A member 1 [NCBI NR] gi\|4972583\|gb\|AAD34706.1\|AF067820_1 ATPase II [Homo sapiens] [NCBI NR] gi\|17978471\|ref\|NP_006086.1\| ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 isoform a [Homo sapiens] [NCBI NR] gi\|119613410\|gb\|EAW93004.1\| ATPase, aminophospholipid transporter (APLT), Class I, type 8A, member 1, isoform CRA_b [Homo sapiens] [NCBI NR] ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 [HGNC (HUGO)] Phospholipid-transporting ATPase IA OS=Homo sapiens GN=ATP8A1 PE=1 SV=1 [Swiss-Prot] (Q9Y2Q0) Potential phospholipid-transporting ATPase IA (EC 3.6.3.1) (Chromaffin granule ATPase II) (ATPase class I type 8A member 1) [Swiss-Prot] Splice isoform Long of Q9Y2Q0 [hmr_yeast5_DM3-1_pombe.fasta] ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1; ATPase II; aminophospholipid translocase [HMR_022704.fasta] ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 [Homo sapiens]gi\|8134331\|sp\|Q9Y2Q0\|A8A1_HUMAN Potential phospholipid-transporting ATPase IA (Chromaffin granule ATPase II) (ATPase class I type 8A member 1)gi\|4972583\|gb\|AAD34706.1 [nrdb_11152004_Chlamydomonas] Potential phospholipid-transporting ATPase IA (Chromaffin granule ATPase II) (ATPase class I type 8A member 1) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Splice Isoform Long of Probable phospholipid-transporting ATPase IA [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_006095) ATPase, aminophospholipid transporter (APLT), Class I, type 8A, member 1; aminophospholipid translocase; ATPase II; PS translocase; Chromaffin granule ATPase II; phospholipid-transporting ATPase IA [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] Tax_Id=9606 Splice Isoform Long of Potential phospholipid-transporting ATPase IA [EBI-IPI_human_3.04_03-07-2005_reverse.fasta] ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1; ATPase II; aminophospholipid translocase [Homo sapiens] [HumanGallus06162005.fasta] ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 isoform a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Probable phospholipid-transporting ATPase IA (Chromaffin granule ATPase II) (ATPase class I type 8A member 1) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] ATPase, aminophospholipid transporter (APLT), Class I, type 8A, member 1, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] ATPase II [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 Isoform Long of Probable phospholipid-transporting ATPase IA [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta] Tax_Id=9606 SPLICE ISOFORM 1 OF POTENTIAL PHOSPHOLIPID-TRANSPORTING ATPASE IA [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=ATP8A1 Isoform Long of Probable phospholipid-transporting ATPase IA [human-ipi-250309-contam.fasta] IPI:IPI00032402.1\|SWISS-PROT:Q9Y2Q0-1\|TREMBL:Q59EX4\|ENSEMBL:ENSP00000371084\|REFSEQ:NP_006086\|H-INV:HIT000065580\|VEGA:OTTHUMP00000125252 Tax_Id=9606 Gene_Symbol=ATP8A1 Isoform Long of Probable phospholipid-transporting ATPase IA [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=ATP8A1 Isoform Long of Probable phospholipid-transporting ATPase IA ENSG00000124406 IPI00221038 IPI00032402 [drosphohumanreversed.fasta] probable phospholipid-transporting ATPase IA isoform a [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Probable phospholipid-transporting ATPase IA OS=Homo sapiens GN=ATP8A1 PE=1 SV=1 [UniProtHuman070710.fasta] Q9Y2Q0; RecName: Full=Probable phospholipid-transporting ATPase IA; AltName: Full=Chromaffin granule ATPase II; AltName: Full=ATPase class I type 8A member 1; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Isoform Long of Probable phospholipid-transporting ATPase IA OS=Homo sapiens GN=ATP8A1 [011711_HMR.fasta] GeneSymbol=ATP8A1 Synonyms=ATPASEII\|ATPIA\|ATPP2\|MGC130042\|MGC130043\|MGC26327 probable phospholipid-transporting ATPase IA isoform a [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] Isoform 1 of Probable phospholipid-transporting ATPase IA OS=Homo sapiens GN=ATP8A1 [122011_hum.fasta] IPI:IPI00032402.1\|SWISS-PROT:Q9Y2Q0-1\|TREMBL:E7EUK4;Q59EX4\|ENSEMBL:ENSP00000371084\|REFSEQ:NP_006086\|H-INV:HIT000065580\|VEGA:OTTHUMP00000125252 Tax_Id=9606 Gene_Symbol=ATP8A1 Isoform 1 of Probable phospholipid-transporting ATPase IA [ipi.HUMAN.20110912.fasta] Probable phospholipid-transporting ATPase IA GN=ATP8A1 [Doctor+uniprot-HUMAN-120911.fasta] Tax_Id=9606 Gene_Symbol=ATP8A1 Isoform 1 of Probable phospholipid-transporting ATPase IA [human-ipi-270911-contam-BSA.fasta]
Organism:	Homo sapiens
Length:	1164 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTMRRTVSE IRSRAEGYEK TDDVSEKTSL ADQEEVRTIF INQPQLTKFC NNHVSTAKYN  60
   61 IITFLPRFLY SQFRRAANSF FLFIALLQQI PDVSPTGRYT TLVPLLFILA VAAIKEIIED 120
  121 IKRHKADNAV NKKQTQVLRN GAWEIVHWEK VAVGEIVKVT NGEHLPADLI SLSSSEPQAM 180
  181 CYIETSNLDG ETNLKIRQGL PATSDIKDVD SLMRISGRIE CESPNRHLYD FVGNIRLDGH 240
  241 GTVPLGADQI LLRGAQLRNT QWVHGIVVYT GHDTKLMQNS TSPPLKLSNV ERITNVQILI 300
  301 LFCILIAMSL VCSVGSAIWN RRHSGKDWYL NLNYGGASNF GLNFLTFIIL FNNLIPISLL 360
  361 VTLEVVKFTQ AYFINWDLDM HYEPTDTAAM ARTSNLNEEL GQVKYIFSDK TGTLTCNVMQ 420
  421 FKKCTIAGVA YGHVPEPEDY GCSPDEWQNS QFGDEKTFSD SSLLENLQNN HPTAPIICEF 480
  481 LTMMAVCHTA VPEREGDKII YQAASPDEGA LVRAAKQLNF VFTGRTPDSV IIDSLGQEER 540
  541 YELLNVLEFT SARKRMSVIV RTPSGKLRLY CKGADTVIYD RLAETSKYKE ITLKHLEQFA 600
  601 TEGLRTLCFA VAEISESDFQ EWRAVYQRAS TSVQNRLLKL EESYELIEKN LQLLGATAIE 660
  661 DKLQDQVPET IETLMKADIK IWILTGDKQE TAINIGHSCK LLKKNMGMIV INEGSLDGTR 720
  721 ETLSRHCTTL GDALRKENDF ALIIDGKTLK YALTFGVRQY FLDLALSCKA VICCRVSPLQ 780
  781 KSEVVEMVKK QVKVVTLAIG DGANDVSMIQ TAHVGVGISG NEGLQAANSS DYSIAQFKYL 840
  841 KNLLMIHGAW NYNRVSKCIL YCFYKNIVLY IIEIWFAFVN GFSGQILFER WCIGLYNVMF 900
  901 TAMPPLTLGI FERSCRKENM LKYPELYKTS QNALDFNTKV FWVHCLNGLF HSVILFWFPL 960
  961 KALQYGTAFG NGKTSDYLLL GNFVYTFVVI TVCLKAGLET SYWTWFSHIA IWGSIALWVV1020
 1021 FFGIYSSLWP AIPMAPDMSG EAAMLFSSGV FWMGLLFIPV ASLLLDVVYK VIKRTAFKTL1080
 1081 VDEVQELEAK SQDPGAVVLG KSLTERAQLL KNVFKKNHVN LYRSESLQQN LLHGYAFSQD1140
 1141 ENGIVSQSEV IRAYDTTKQR PDEW

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..1091]	PSI-BLAST	165.0	Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M
2	View Details	[1092..1164]	deduced	N/A	No confident structure predictions are available.

Protein Overview: ATP8A1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: