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Protein Overview: CLNS1A

General Information:
Name(s) found: CLNS1A [HGNC (HUGO)]
Description(s) found:
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  • gi|8571384|gb|AAF76858.1| chloride ion current inducer protein I(Cln) [Homo sapiens] [NCBI NR]
  • gi|717054|gb|AAC50111.1| chloride channel regulatory protein [NCBI NR]
  • gi|54696676|gb|AAV38710.1| chloride channel, nucleotide-sensitive, 1A [Homo sapiens] [NCBI NR]
  • gi|4502891|ref|NP_001284.1| chloride channel, nucleotide-sensitive, 1A [Homo sapiens] [NCBI NR]
  • gi|2570862|gb|AAB88806.1| chloride ion current inducer protein [Homo sapiens] [NCBI NR]
  • gi|2209235|gb|AAB61444.1| reticulocyte pICln [Homo sapiens] [NCBI NR]
  • gi|189055318|dbj|BAG37676.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|1708393|sp|P54105.1|ICLN_HUMAN RecName: Full=Methylosome subunit pICln; AltName: Full=Chloride conductance regulatory protein ICln; Short=I(Cln); AltName: Full=Chloride channel, nucleotide sensitive 1A; AltName: Full=Chloride ion current inducer protei [NCBI NR]
  • gi|1399646|gb|AAB03316.1| chloride ion current inducer protein [NCBI NR]
  • gi|119595438|gb|EAW75032.1| chloride channel, nucleotide-sensitive, 1A [Homo sapiens] [NCBI NR]
  • gi|110645852|gb|AAI19636.1| Chloride channel, nucleotide-sensitive, 1A [Homo sapiens] [NCBI NR]
  • gi|110645850|gb|AAI19635.1| Chloride channel, nucleotide-sensitive, 1A [Homo sapiens] [NCBI NR]
  • pir||JC4135 chloride conductance regulatory protein, pICln - human [NCBI NR]
  • gi|1001875|emb|CAA62902.1| Icln protein [Homo sapiens] [NCBI NR]
  • chloride channel, nucleotide-sensitive, 1A [HGNC (HUGO)]
  • Methylosome subunit pICln OS=Homo sapiens GN=CLNS1A PE=1 SV=1 [Swiss-Prot]
  • Methylosome subunit pICln [hmr_yeast5_DM3-1_pombe.fasta]
  • chloride channel, nucleotide-sensitive, 1A [Homo sapiens]gi|4502891|ref|NP_001284.1| chloride channel, nucleotide-sensitive, 1A [Homo sapiens]gi|8571384|gb|AAF76858.1| chloride ion current inducer protein I(Cln) [Homo sapiens]gi|1708393|sp|P54105|ICLN_ [nrdb_11152004_Chlamydomonas]
  • Methylosome subunit pICln (Chloride conductance regulatory protein ICln) (I(Cln)) (Chloride channel, nucleotide sensitive 1A) (Chloride ion current inducer protein) (ClCI) (Reticulocyte pICln) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Methylosome subunit pICln [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_001293) chloride channel, nucleotide-sensitive, 1A [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • chloride channel, nucleotide-sensitive, 1A [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Methylosome subunit pICln [EBI-IPI_Drosophila_na_12-13-2007_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chloride channel, nucleotide-sensitive, 1A [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • chloride ion current inducer protein I(Cln) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • chloride channel regulatory protein [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • chloride ion current inducer protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • reticulocyte pICln [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • chloride ion current inducer protein [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Icln protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 METHYLOSOME SUBUNIT PICLN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=CLNS1A Methylosome subunit pICln [human-ipi-250309-contam.fasta]
  • IPI:IPI00004795.1|SWISS-PROT:P54105|TREMBL:Q9P1H0|ENSEMBL:ENSP00000263309|REFSEQ:NP_001284|H-INV:HIT000324464 Tax_Id=9606 Gene_Symbol=CLNS1A Methylosome subunit pICln [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=CLNS1A Methylosome subunit pICln ENSG00000074201 IPI00004795 [drosphohumanreversed.fasta]
  • P54105;B2RCS9;Q0VDK6;Q9NRD2;Q9NRD3; RecName: Full=Methylosome subunit pICln; AltName: Full=Chloride conductance regulatory protein ICln; AltName: Full=Chloride channel, nucleotide sensitive 1A; AltName: Full=Chloride ion current inducer protein; AltName: Full=Reticulocyte pICln; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Methylosome subunit pICln OS=Homo sapiens GN=CLNS1A [011711_HMR.fasta]
  • GeneSymbol=CLNS1A Synonyms=CLCI|CLNS1B|ICln methylosome subunit pICln [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00004795.1|SWISS-PROT:P54105|ENSEMBL:ENSP00000433919;ENSP00000434311|REFSEQ:NP_001284|H-INV:HIT000324464|VEGA:OTTHUMP00000228612;OTTHUMP00000228845 Tax_Id=9606 Gene_Symbol=CLNS1A Methylosome subunit pICln [ipi.HUMAN.20110912.fasta]
  • Methylosome subunit pICln GN=CLNS1A [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 237 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFLKSFPPP GPAEGLLRQQ PDTEAVLNGK GLGTGTLYIA ESRLSWLDGS GLGFSLEYPT  60
   61 ISLHALSRDR SDCLGEHLYV MVNAKFEEES KEPVADEEEE DSDDDVEPIT EFRFVPSDKS 120
  121 ALEAMFTAMC ECQALHPDPE DEDSDDYDGE EYDVEAHEQG QGDIPTFYTY EEGLSHLTAE 180
  181 GQATLERLEG MLSQSVSSQY NMAGVRTEDS IRDYEDGMEV DTTPTVAGQF EDADVDH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..163] PSI-BLAST 54.522879 Solution structure of ICLN, a multifunctional protein involved in regulatory mechanisms as different as cell volume regulation and rna splicing
    2 View Details [164..237] MSA 1.030981 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle