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Protein Overview: OTUD5

General Information:
Name(s) found: OTUD5 [HGNC (HUGO)]
Description(s) found:
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  • gi|74731791|sp|Q96G74.1|OTUD5_HUMAN RecName: Full=OTU domain-containing protein 5; AltName: Full=Deubiquinating enzyme A; Short=DUBA [NCBI NR]
  • gi|33457350|ref|NP_060072.1| OTU domain containing 5 isoform a [Homo sapiens] [NCBI NR]
  • gi|14602829|gb|AAH09917.1| OTU domain containing 5 [Homo sapiens] [NCBI NR]
  • gi|119571111|gb|EAW50726.1| OTU domain containing 5, isoform CRA_d [Homo sapiens] [NCBI NR]
  • gi|119571110|gb|EAW50725.1| OTU domain containing 5, isoform CRA_d [Homo sapiens] [NCBI NR]
  • OTU domain containing 5 [HGNC (HUGO)]
  • OTU domain-containing protein 5 OS=Homo sapiens GN=OTUD5 PE=1 SV=1 [Swiss-Prot]
  • Hypothetical protein [hmr_yeast5_DM3-1_pombe.fasta]
  • hypothetical protein DKFZp761A052 [HMR_022704.fasta]
  • hypothetical protein DKFZp761A052 [Homo sapiens]gi|14602829|gb|AAH09917.1| Hypothetical protein DKFZp761A052 [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 Hypothetical protein OTUD5 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • OTU domain containing 5 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Hypothetical protein DKFZp761A052 [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • hypothetical protein DKFZp761A052 [Homo sapiens] [HumanGallus06162005.fasta]
  • OTU domain-containing protein 5 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • OTU domain containing 5, isoform CRA_d [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 OTU domain containing 5 [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 HYPOTHETICAL PROTEIN DKFZP761A052 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=OTU domain-containing protein 5; AltName: Full=Deubiquinating enzyme A; Short=DUBA [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • OTU domain containing 5 isoform a [Homo sapiens] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=OTUD5 Isoform 1 of OTU domain-containing protein 5 [human-ipi-250309-contam.fasta]
  • IPI:IPI00640364.2|SWISS-PROT:Q96G74-1|ENSEMBL:ENSP00000156084|REFSEQ:NP_060072|H-INV:HIT000034669|VEGA:OTTHUMP00000025821 Tax_Id=9606 Gene_Symbol=OTUD5 Isoform 1 of OTU domain-containing protein 5 [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Isoform 1 of OTU domain-containing protein 5 [IPI_human_3.26.fasta]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=OTUD5 Isoform 1 of OTU domain-containing protein 5 ENSG00000068308 IPI00640364 IPI00641956 IPI00062321 IPI00827562 [drosphohumanreversed.fasta]
  • OTU domain-containing protein 5 isoform a [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q96G74;Q4KMN9;Q8N6T5;Q9H650;Q9H9U0;Q9NT65; RecName: Full=OTU domain-containing protein 5; AltName: Full=Deubiquitinating enzyme A; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of OTU domain-containing protein 5 OS=Homo sapiens GN=OTUD5 [011711_HMR.fasta]
  • GeneSymbol=OTUD5 Synonyms=DKFZp761A052|DUBA|MGC104871 OTU domain-containing protein 5 isoform a [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • OTU domain-containing protein 5 GN=OTUD5 [Doctor+uniprot-HUMAN-120911.fasta]
  • OTU domain containing 5, isoform CRA_d OS=Homo sapiens GN=OTUD5 PE=4 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 571 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTILPKKKPP PPDADPANEP PPPGPMPPAP RRGGGVGVGG GGTGVGGGDR DRDSGVVGAR  60
   61 PRASPPPQGP LPGPPGALHR WALAVPPGAV AGPRPQQASP PPCGGPGGPG GGPGDALGAA 120
  121 AAGVGAAGVV VGVGGAVGVG GCCSGPGHSK RRRQAPGVGA VGGGSPEREE VGAGYNSEDE 180
  181 YEAAAARIEA MDPATVEQQE HWFEKALRDK KGFIIKQMKE DGACLFRAVA DQVYGDQDMH 240
  241 EVVRKHCMDY LMKNADYFSN YVTEDFTTYI NRKRKNNCHG NHIEMQAMAE MYNRPVEVYQ 300
  301 YSTGTSAVEP INTFHGIHQN EDEPIRVSYH RNIHYNSVVN PNKATIGVGL GLPSFKPGFA 360
  361 EQSLMKNAIK TSEESWIEQQ MLEDKKRATD WEATNEAIEE QVARESYLQW LRDQEKQARQ 420
  421 VRGPSQPRKA SATCSSATAA ASSGLEEWTS RSPRQRSSAS SPEHPELHAE LGMKPPSPGT 480
  481 VLALAKPPSP CAPGTSSQFS AGADRATSPL VSLYPALECR ALIQQMSPSA FGLNDWDDDE 540
  541 ILASVLAVSQ QEYLDSMKKN KVHRDPPPDK S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..197] PSI-BLAST 5.69897 No description for 1y0fB was found.
    2 View Details [198..351] PSI-BLAST 7.045757 Structure of Otubain-2
    3 View Details [352..472] FFAS03 1.0 Crystal structure of human pregnenolone sulfotransferase (SULT2B1a) in the presence of PAP
    4 View Details [473..571] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  0.529663942126259 bayes_pls_golite062009
  • hydrolase activity
    		•  0.16837900182603 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.57

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle