Protein Overview: CALCA

General Information:
Name(s) found:	CALCA [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|76880478\|ref\|NP_001029125.1\| calcitonin isoform CGRP preproprotein [Homo sapiens] [NCBI NR] gi\|296638\|emb\|CAA34070.1\| cgrp propeptide [Homo sapiens] [NCBI NR] pir\|\|TCHUR calcitonin gene-related peptide alpha precursor [validated] - human [NCBI NR] gi\|179828\|gb\|AAA51914.1\| preprocalcitonin gene-related protein [NCBI NR] gi\|119588875\|gb\|EAW68469.1\| calcitonin/calcitonin-related polypeptide, alpha, isoform CRA_b [Homo sapiens] [NCBI NR] gi\|115482\|sp\|P06881.2\|CALCA_HUMAN RecName: Full=Calcitonin gene-related peptide 1; AltName: Full=Calcitonin gene-related peptide I; Short=CGRP-I; AltName: Full=Alpha-type CGRP; Flags: Precursor [NCBI NR] calcitonin-related polypeptide alpha [HGNC (HUGO)] Calcitonin gene-related peptide 1 OS=Homo sapiens GN=CALCA PE=1 SV=2 [Swiss-Prot] (P06881) Calcitonin gene-related peptide I precursor (CGRP-I) (Alpha-type CGRP) [Swiss-Prot] Calcitonin gene-related peptide I precursor [hmr_yeast5_DM3-1_pombe.fasta] calcitonin gene-related peptide alpha precursor [validated] - humangi\|296638\|emb\|CAA34070.1\| cgrp propeptide [Homo sapiens]gi\|179828\|gb\|AAA51914.1\| preprocalcitonin gene-related proteingi\|115482\|sp\|P06881\|CAL1_HUMAN Calcitonin gene-related peptide I pr [nrdb_11152004_Chlamydomonas] Calcitonin gene-related peptide I precursor (CGRP-I) (Alpha-type CGRP) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Calcitonin gene-related peptide 1 precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] calcitonin isoform CGRP preproprotein [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] Tax_Id=9606 Calcitonin gene-related peptide I precursor [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta] Calcitonin gene-related peptide 1 precursor (Calcitonin gene-related peptide I) (CGRP-I) (Alpha-type CGRP) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] calcitonin/calcitonin-related polypeptide, alpha, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] cgrp propeptide [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] preprocalcitonin gene-related protein [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 CALCITONIN GENE-RELATED PEPTIDE I PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] RecName: Full=Calcitonin gene-related peptide 1; AltName: Full=Calcitonin gene-related peptide I; Short=CGRP-I; AltName: Full=Alpha-type CGRP; Flags: Precursor [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=CALCA Calcitonin gene-related peptide 1 [human-ipi-250309-contam.fasta] calcitonin/calcitonin-related polypeptide, alpha isoform CGRP preproprotein [Homo sapiens] [NCBI-RefSeq_Human_na_02-15-2010_reversed.fasta] IPI:IPI00027855.1\|SWISS-PROT:P06881\|ENSEMBL:ENSP00000354286;ENSP00000379659\|REFSEQ:NP_001029125 Tax_Id=9606 Gene_Symbol=CALCA Calcitonin gene-related peptide 1 [ipi.HUMAN.fasta.20090807] Tax_Id=9606 Gene_Symbol=CALCA Calcitonin gene-related peptide 1 precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta] calcitonin gene-related peptide 1 preproprotein [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] P06881;Q93048;Q9UCP0; RecName: Full=Calcitonin gene-related peptide 1; AltName: Full=Calcitonin gene-related peptide I; AltName: Full=Alpha-type CGRP; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] IPI:IPI00027855.1\|SWISS-PROT:P06881\|ENSEMBL:ENSP00000354286;ENSP00000379659;ENSP00000417833\|REFSEQ:NP_001029125 Tax_Id=9606 Gene_Symbol=CALCA Calcitonin gene-related peptide 1 [ipi.HUMAN.fasta.20100406] GeneSymbol=CALCA Synonyms=CALC1\|CGRP\|CGRP-I\|CGRP1\|CT\|KC\|MGC126648 calcitonin gene-related peptide 1 preproprotein [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] Calcitonin gene-related peptide 1 OS=Homo sapiens GN=CALCA PE=1 SV=3 VAR_048584 [swiss.HUMAN.20141123.contam.amyloid.poly.fasta]
Organism:	Homo sapiens
Length:	128 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MGFQKFSPFL ALSILVLLQA GSLHAAPFRS ALESSPADPA TLSEDEARLL LAALVQDYVQ 60 61 MKASELEQEQ EREGSRIIAQ KRACDTATCV THRLAGLLSR SGGVVKNNFV PTNVGSKAFG 120 121 RRRRDLQA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..128]	deduced	N/A	Confident ab initio structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
binding	2.2912619716107	bayes_pls_golite062009
protein binding	1.9593327660138	bayes_pls_golite062009
ion transmembrane transporter activity	1.19752781612021	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.06747829758878	bayes_pls_golite062009
ion channel inhibitor activity	0.728958862998098	bayes_pls_golite062009
channel inhibitor activity	0.728958862998098	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

Philius confidence legend

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