Protein Overview: CACNA1B

General Information:
Name(s) found:	CACNA1B [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|57209533\|emb\|CAI40687.1\| calcium channel, voltage-dependent, N type, alpha 1B subunit [Homo sapiens] [NCBI NR] gi\|55962841\|emb\|CAI17144.1\| calcium channel, voltage-dependent, N type, alpha 1B subunit [Homo sapiens] [NCBI NR] gi\|4502523\|ref\|NP_000709.1\| calcium channel, voltage-dependent, N type, alpha 1B subunit [Homo sapiens] [NCBI NR] gi\|179758\|gb\|AAA51897.1\| N-type calcium channel alpha-1 subunit [Homo sapiens] [NCBI NR] gi\|1705854\|sp\|Q00975.1\|CAC1B_HUMAN RecName: Full=Voltage-dependent N-type calcium channel subunit alpha-1B; AltName: Full=Voltage-gated calcium channel subunit alpha Cav2.2; AltName: Full=Calcium channel, L type, alpha-1 polypeptide isoform 5; AltName: Fu [NCBI NR] calcium channel, voltage-dependent, N type, alpha 1B subunit [HGNC (HUGO)] (Q00975) Voltage-dependent N-type calcium channel alpha-1B subunit (Voltage-gated calcium channel alpha subunit Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII) [Swiss-Prot] Voltage-dependent N-type calcium channel subunit alpha-1B OS=Homo sapiens GN=CACNA1B PE=1 SV=1 [Swiss-Prot] Splice isoform Alpha-1B-1 of Q00975 [hmr_yeast5_DM3-1_pombe.fasta] calcium channel, voltage-dependent, L type, alpha 1B subunit; calcium channel, N type; calcium channel, voltage-dependent, alpha 1B subunit, N type [HMR_022704.fasta] calcium channel, voltage-dependent, L type, alpha 1B subunit [Homo sapiens]gi\|1705854\|sp\|Q00975\|CCAB_HUMAN Voltage-dependent N-type calcium channel alpha-1B subunit (Voltage-gated calcium channel alpha subunit Cav2.2) (Calcium channel, L type, alpha-1 po [nrdb_11152004_Chlamydomonas] Voltage-dependent N-type calcium channel alpha-1B subunit (Voltage-gated calcium channel alpha subunit Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Splice Isoform Alpha-1B-1 of Voltage-dependent N-type calcium channel alpha-1B subunit [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_000718) calcium channel, voltage-dependent, L type, alpha 1B subunit; calcium channel, N type; calcium channel, voltage-dependent, alpha 1B subunit, N type [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] calcium channel, voltage-dependent, L type, alpha 1B subunit [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] calcium channel, voltage-dependent, L type, alpha 1B subunit; calcium channel, N type; calcium channel, voltage-dependent, alpha 1B subunit, N type [Homo sapiens] [HumanGallus06162005.fasta] Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage-gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] calcium channel, voltage-dependent, N type, alpha 1B subunit [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] N-type calcium channel alpha-1 subunit [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 Isoform Alpha-1B-1 of Voltage-dependent N-type calcium channel subunit alpha-1B [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=CACNA1B Isoform Alpha-1B-1 of Voltage-dependent N-type calcium channel subunit alpha-1B ENSG00000148408 IPI00025477 IPI00029505 IPI00643852 IPI00029502 IPI00642867 IPI00645750 IPI00553112 IPI00744508 IPI00220431 IPI00815762 [drosphohumanreversed.fasta] Tax_Id=9606 Gene_Symbol=CACNA1B Isoform Alpha-1B-1 of Voltage-dependent N-type calcium channel subunit alpha-1B [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta] voltage-dependent N-type calcium channel subunit alpha-1B [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Q00975;B1AQK5; RecName: Full=Voltage-dependent N-type calcium channel subunit alpha-1B; AltName: Full=Voltage-gated calcium channel subunit alpha Cav2.2; AltName: Full=Calcium channel, L type, alpha-1 polypeptide isoform 5; AltName: Full=Brain calcium channel III; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Isoform Alpha-1B-1 of Voltage-dependent N-type calcium channel subunit alpha-1B OS=Homo sapiens GN=CACNA1B [011711_HMR.fasta] GeneSymbol=CACNA1B Synonyms=BIII\|CACNL1A5\|CACNN\|Cav2.2 voltage-dependent N-type calcium channel subunit alpha-1B [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] Voltage-dependent N-type calcium channel subunit alpha-1B GN=CACNA1B [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	2339 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRFGDELGG RYGGPGGGER ARGGGAGGAG GPGPGGLQPG QRVLYKQSIA QRARTMALYN  60
   61 PIPVKQNCFT VNRSLFVFSE DNVVRKYAKR ITEWPPFEYM ILATIIANCI VLALEQHLPD 120
  121 GDKTPMSERL DDTEPYFIGI FCFEAGIKII ALGFVFHKGS YLRNGWNVMD FVVVLTGILA 180
  181 TAGTDFDLRT LRAVRVLRPL KLVSGIPSLQ VVLKSIMKAM VPLLQIGLLL FFAILMFAII 240
  241 GLEFYMGKFH KACFPNSTDA EPVGDFPCGK EAPARLCEGD TECREYWPGP NFGITNFDNI 300
  301 LFAILTVFQC ITMEGWTDIL YNTNDAAGNT WNWLYFIPLI IIGSFFMLNL VLGVLSGEFA 360
  361 KERERVENRR AFLKLRRQQQ IERELNGYLE WIFKAEEVML AEEDRNAEEK SPLDVLKRAA 420
  421 TKKSRNDLIH AEEGEDRFAD LCAVGSPFAR ASLKSGKTES SSYFRRKEKM FRFFIRRMVK 480
  481 AQSFYWVVLC VVALNTLCVA MVHYNQPRRL TTTLYFAEFV FLGLFLTEMS LKMYGLGPRS 540
  541 YFRSSFNCFD FGVIVGSVFE VVWAAIKPGS SFGISVLRAL RLLRIFKVTK YWSSLRNLVV 600
  601 SLLNSMKSII SLLFLLFLFI VVFALLGMQL FGGQFNFQDE TPTTNFDTFP AAILTVFQIL 660
  661 TGEDWNAVMY HGIESQGGVS KGMFSSFYFI VLTLFGNYTL LNVFLAIAVD NLANAQELTK 720
  721 DEEEMEEAAN QKLALQKAKE VAEVSPMSAA NISIAARQQN SAKARSVWEQ RASQLRLQNL 780
  781 RASCEALYSE MDPEERLRFA TTRHLRPDMK THLDRPLVVE LGRDGARGPV GGKARPEAAE 840
  841 APEGVDPPRR HHRHRDKDKT PAAGDQDRAE APKAESGEPG AREERPRPHR SHSKEAAGPP 900
  901 EARSERGRGP GPEGGRRHHR RGSPEEAAER EPRRHRAHRH QDPSKECAGA KGERRARHRG 960
  961 GPRAGPREAE SGEEPARRHR ARHKAQPAHE AVEKETTEKE ATEKEAEIVE ADKEKELRNH1020
 1021 QPREPHCDLE TSGTVTVGPM HTLPSTCLQK VEEQPEDADN QRNVTRMGSQ PPDPNTIVHI1080
 1081 PVMLTGPLGE ATVVPSGNVD LESQAEGKKE VEADDVMRSG PRPIVPYSSM FCLSPTNLLR1140
 1141 RFCHYIVTMR YFEVVILVVI ALSSIALAAE DPVRTDSPRN NALKYLDYIF TGVFTFEMVI1200
 1201 KMIDLGLLLH PGAYFRDLWN ILDFIVVSGA LVAFAFSGSK GKDINTIKSL RVLRVLRPLK1260
 1261 TIKRLPKLKA VFDCVVNSLK NVLNILIVYM LFMFIFAVIA VQLFKGKFFY CTDESKELER1320
 1321 DCRGQYLDYE KEEVEAQPRQ WKKYDFHYDN VLWALLTLFT VSTGEGWPMV LKHSVDATYE1380
 1381 EQGPSPGYRM ELSIFYVVYF VVFPFFFVNI FVALIIITFQ EQGDKVMSEC SLEKNERACI1440
 1441 DFAISAKPLT RYMPQNRQSF QYKTWTFVVS PPFEYFIMAM IALNTVVLMM KFYDAPYEYE1500
 1501 LMLKCLNIVF TSMFSMECVL KIIAFGVLNY FRDAWNVFDF VTVLGSITDI LVTEIAETNN1560
 1561 FINLSFLRLF RAARLIKLLR QGYTIRILLW TFVQSFKALP YVCLLIAMLF FIYAIIGMQV1620
 1621 FGNIALDDDT SINRHNNFRT FLQALMLLFR SATGEAWHEI MLSCLSNQAC DEQANATECG1680
 1681 SDFAYFYFVS FIFLCSFLML NLFVAVIMDN FEYLTRDSSI LGPHHLDEFI RVWAEYDPAA1740
 1741 CGRISYNDMF EMLKHMSPPL GLGKKCPARV AYKRLVRMNM PISNEDMTVH FTSTLMALIR1800
 1801 TALEIKLAPA GTKQHQCDAE LRKEISVVWA NLPQKTLDLL VPPHKPDEMT VGKVYAALMI1860
 1861 FDFYKQNKTT RDQMQQAPGG LSQMGPVSLF HPLKATLEQT QPAVLRGARV FLRQKSSTSL1920
 1921 SNGGAIQNQE SGIKESVSWG TQRTQDAPHE ARPPLERGHS TEIPVGRSGA LAVDVQMQSI1980
 1981 TRRGPDGEPQ PGLESQGRAA SMPRLAAETQ PVTDASPMKR SISTLAQRPR GTHLCSTTPD2040
 2041 RPPPSQASSH HHHHRCHRRR DRKQRSLEKG PSLSADMDGA PSSAVGPGLP PGEGPTGCRR2100
 2101 ERERRQERGR SQERRQPSSS SSEKQRFYSC DRFGGREPPK PKPSLSSHPT SPTAGQEPGP2160
 2161 HPQGSGSVNG SPLLSTSGAS TPGRGGRRQL PQTPLTPRPS ITYKTANSSP IHFAGAQTSL2220
 2221 PAFSPGRLSR GLSEHNALLQ RDPLSQPLAP GSRIGSDPYL GQRLDSEASV HALPEDTLTF2280
 2281 EEAVATNSGR SSRTSYVSSL TSQSHPLRRV PNGYHCTLGL SSGGRARHSY HHPDQDHWC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MIS12	No Comments	Cheeseman, I.M., et al. (2004)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: CACNA1B

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: