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Protein Overview: OSM

General Information:
Name(s) found: OSM [HGNC (HUGO)]
Description(s) found:
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  • gi|49456367|emb|CAG46504.1| OSM [Homo sapiens] [NCBI NR]
  • gi|47678599|emb|CAG30420.1| OSM [Homo sapiens] [NCBI NR]
  • gi|386988|gb|AAA36388.1| oncostatin M [NCBI NR]
  • gi|2935614|gb|AAC05173.1| oncostatin M precursor [Homo sapiens] [NCBI NR]
  • gi|15079523|gb|AAH11589.1| Oncostatin M [Homo sapiens] [NCBI NR]
  • gi|129168|sp|P13725.2|ONCM_HUMAN RecName: Full=Oncostatin-M; Short=OSM; Flags: Precursor [NCBI NR]
  • gi|119580268|gb|EAW59864.1| oncostatin M, isoform CRA_a [Homo sapiens] [NCBI NR]
  • pir||A32489 oncostatin M precursor - human [NCBI NR]
  • gi|10092621|ref|NP_065391.1| oncostatin M precursor [Homo sapiens] [NCBI NR]
  • oncostatin M [HGNC (HUGO)]
  • Oncostatin-M OS=Homo sapiens GN=OSM PE=1 SV=2 [Swiss-Prot]
  • Oncostatin M precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • oncostatin M precursor [HMR_022704.fasta]
  • oncostatin M precursor [Homo sapiens]gi|15079523|gb|AAH11589.1| Oncostatin M, precursor [Homo sapiens]gi|2935614|gb|AAC05173.1| oncostatin M precursor [Homo sapiens]gi|107241|pir||A32489 oncostatin M precursor - humangi|49456367|emb|CAG46504.1| OSM [H [nrdb_11152004_Chlamydomonas]
  • Oncostatin M precursor (OSM) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Oncostatin M precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_020530) oncostatin M [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • oncostatin M precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • OSM [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Oncostatin-M precursor (OSM) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • oncostatin M, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Oncostatin M [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 ONCOSTATIN M PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Oncostatin-M; Short=OSM; Flags: Precursor [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=OSM Oncostatin-M [human-ipi-250309-contam.fasta]
  • IPI:IPI00010336.1|SWISS-PROT:P13725|ENSEMBL:ENSP00000215781|REFSEQ:NP_065391|H-INV:HIT000035313|VEGA:OTTHUMP00000028540;OTTHUMP00000198700 Tax_Id=9606 Gene_Symbol=OSM Oncostatin-M [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Oncostatin-M precursor [IPI_human_3.26.fasta]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=OSM Oncostatin-M precursor ENSG00000099985 IPI00010336 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=OSM Oncostatin-M precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • oncostatin-M precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P13725;Q6FHP8;Q9UCP6; RecName: Full=Oncostatin-M; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Oncostatin-M OS=Homo sapiens GN=OSM [011711_HMR.fasta]
  • GeneSymbol=OSM Synonyms=MGC20461 oncostatin-M precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00010336.1|SWISS-PROT:P13725|ENSEMBL:ENSP00000215781|REFSEQ:NP_065391|H-INV:HIT000035313|VEGA:OTTHUMP00000198700 Tax_Id=9606 Gene_Symbol=OSM Oncostatin-M [ipi.HUMAN.20110912.fasta]
  • Oncostatin-M GN=OSM [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 252 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVLLTQRTL LSLVLALLFP SMASMAAIGS CSKEYRVLLG QLQKQTDLMQ DTSRLLDPYI  60
   61 RIQGLDVPKL REHCRERPGA FPSEETLRGL GRRGFLQTLN ATLGCVLHRL ADLEQRLPKA 120
  121 QDLERSGLNI EDLEKLQMAR PNILGLRNNI YCMAQLLDNS DTAEPTKAGR GASQPPTPTP 180
  181 ASDAFQRKLE GCRFLHGYHR FMHSVGRVFS KWGESPNRSR RHSPHQALRK GVRRTRPSRK 240
  241 GKRLMTRGQL PR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..252] PSI-BLAST 87.69897 Oncostatin M

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ciliary neurotrophic factor receptor binding
    		•  7.7149955236337 bayes_pls_golite062009
  • cytokine receptor binding
    		•  6.47223189691244 bayes_pls_golite062009
  • receptor binding
    		•  5.3304255990112 bayes_pls_golite062009
  • cytokine activity
    		•  5.1883241815362 bayes_pls_golite062009
  • growth factor activity
    		•  4.92105782010612 bayes_pls_golite062009
  • oncostatin-M receptor binding
    		•  4.90961029698962 bayes_pls_golite062009
  • protein binding
    		•  3.52041127390038 bayes_pls_golite062009
  • binding
    		•  2.74412602806415 bayes_pls_golite062009
  • hormone activity
    		•  2.52921243340076 bayes_pls_golite062009
  • prolactin receptor binding
    		•  2.45721634350294 bayes_pls_golite062009
  • growth hormone activity
    		•  2.40761961528911 bayes_pls_golite062009
  • interleukin-6 receptor binding
    		•  2.37535614986843 bayes_pls_golite062009
  • macrophage colony stimulating factor receptor binding
    		•  1.79494229909143 bayes_pls_golite062009
  • interleukin-10 receptor binding
    		•  1.70583547295961 bayes_pls_golite062009
  • signal transducer activity
    		•  1.52819399447638 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.52819399447638 bayes_pls_golite062009
  • erythropoietin receptor binding
    		•  1.40250979351968 bayes_pls_golite062009
  • interleukin-5 receptor binding
    		•  0.89757450102906 bayes_pls_golite062009
  • interleukin-27 binding
    		•  0.47086358315465 bayes_pls_golite062009
  • interleukin-12 binding
    		•  0.30601802121141 bayes_pls_golite062009
  • catalytic activity
    		•  0.246169290135575 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle