Protein Overview: UNG

General Information:
Name(s) found:	UNG [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|37999897\|sp\|P13051.2\|UNG_HUMAN RecName: Full=Uracil-DNA glycosylase; Short=UDG [NCBI NR] gi\|21780365\|gb\|AAM77695.1\|AF526277_1 uracil-DNA glycosylase [Homo sapiens] [NCBI NR] gi\|19718751\|ref\|NP_550433.1\| uracil-DNA glycosylase isoform UNG2 [Homo sapiens] [NCBI NR] gi\|189069296\|dbj\|BAG36328.1\| unnamed protein product [Homo sapiens] [NCBI NR] gi\|1850821\|emb\|CAA70211.1\| uracil-DNA glycosylase [Homo sapiens] [NCBI NR] gi\|1654005\|emb\|CAA61578.1\| uracil-DNA-glycosylase, UNG2 [Homo sapiens] [NCBI NR] gi\|119618255\|gb\|EAW97849.1\| uracil-DNA glycosylase, isoform CRA_b [Homo sapiens] [NCBI NR] gi\|119618253\|gb\|EAW97847.1\| uracil-DNA glycosylase, isoform CRA_b [Homo sapiens] [NCBI NR] uracil-DNA glycosylase [HGNC (HUGO)] Uracil-DNA glycosylase OS=Homo sapiens GN=UNG PE=1 SV=2 [Swiss-Prot] Uracil-DNA-glycosylase [hmr_yeast5_DM3-1_pombe.fasta] uracil-DNA glycosylase isoform UNG2; uracil-DNA glycosylase 1 [HMR_022704.fasta] uracil-DNA glycosylase isoform UNG2 [Homo sapiens]gi\|21780365\|gb\|AAM77695.1\| uracil-DNA glycosylase [Homo sapiens]gi\|1850821\|emb\|CAA70211.1\| uracil-DNA glycosylase [Homo sapiens]gi\|1654005\|emb\|CAA61578.1\| uracil-DNA-glycosylase, UNG2 [Homo sapiens]gi\| [nrdb_11152004_Chlamydomonas] Uracil-DNA glycosylase (UDG) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Splice Isoform 2 of Uracil-DNA glycosylase [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_080911) uracil-DNA glycosylase, isoform UNG2; uracil-DNA glycosylase, nuclear; uracil-DNA glycosylase 2 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] uracil-DNA glycosylase isoform UNG2 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] uracil-DNA glycosylase isoform UNG2; uracil-DNA glycosylase 1 [Homo sapiens] [HumanGallus06162005.fasta] unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] uracil-DNA glycosylase, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] uracil-DNA-glycosylase, UNG2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] uracil-DNA glycosylase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] HUMAN URACIL-DNA GLYCOSYLASE 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 Isoform 2 of Uracil-DNA glycosylase [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta] Tax_Id=9606 SPLICE ISOFORM 1 OF URACIL-DNA GLYCOSYLASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=UNG Isoform 2 of Uracil-DNA glycosylase [human-ipi-250309-contam.fasta] IPI:IPI00011069.1\|SWISS-PROT:P13051-1\|TREMBL:B2R8Y1\|ENSEMBL:ENSP00000242576\|REFSEQ:NP_550433\|H-INV:HIT000325494\|VEGA:OTTHUMP00000169121 Tax_Id=9606 Gene_Symbol=UNG Isoform 2 of Uracil-DNA glycosylase [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=UNG Isoform 2 of Uracil-DNA glycosylase ENSG00000076248 IPI00011069 IPI00006516 [drosphohumanreversed.fasta] P13051;A8K5M6;B2R8Y1;O00637;O00719;Q93028; RecName: Full=Uracil-DNA glycosylase; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Isoform 2 of Uracil-DNA glycosylase OS=Homo sapiens GN=UNG [011711_HMR.fasta] IPI:IPI00011069.1\|SWISS-PROT:P13051-1\|ENSEMBL:ENSP00000242576\|REFSEQ:NP_550433\|H-INV:HIT000325494\|VEGA:OTTHUMP00000169121 Tax_Id=9606 Gene_Symbol=UNG Isoform 2 of Uracil-DNA glycosylase [ipi.HUMAN.fasta.20100406] GeneSymbol=UNG Synonyms=DGU\|DKFZp781L1143\|HIGM4\|UDG\|UNG1\|UNG15\|UNG2 uracil-DNA glycosylase isoform UNG2 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00011069.1\|SWISS-PROT:P13051-1\|TREMBL:E5KTA5\|ENSEMBL:ENSP00000242576\|REFSEQ:NP_550433\|H-INV:HIT000325494\|VEGA:OTTHUMP00000240527 Tax_Id=9606 Gene_Symbol=UNG Isoform 2 of Uracil-DNA glycosylase [ipi.HUMAN.20110912.fasta] Uracil-DNA glycosylase GN=UNG [Doctor+uniprot-HUMAN-120911.fasta] Uracil-DNA glycosylase OS=Homo sapiens GN=UNG PE=3 SV=1 [uniprot-human-031015-contam.fasta]
Organism:	Homo sapiens
Length:	313 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIGQKTLYSF FSPSPARKRH APSPEPAVQG TGVAGVPEES GDAAAIPAKK APAGQEEPGT  60
   61 PPSSPLSAEQ LDRIQRNKAA ALLRLAARNV PVGFGESWKK HLSGEFGKPY FIKLMGFVAE 120
  121 ERKHYTVYPP PHQVFTWTQM CDIKDVKVVI LGQDPYHGPN QAHGLCFSVQ RPVPPPPSLE 180
  181 NIYKELSTDI EDFVHPGHGD LSGWAKQGVL LLNAVLTVRA HQANSHKERG WEQFTDAVVS 240
  241 WLNQNSNGLV FLLWGSYAQK KGSAIDRKRH HVLQTAHPSP LSVYRGFFGC RHFSKTNELL 300
  301 QKSGKKPIDW KEL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..91]	MSA	2.115997	View MSA. No confident structure predictions are available.
2	View Details	[92..313]	PSI-BLAST	106.0	Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA N-glycosylase (UNG)from atlantic cod (Gadus morhua)

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: UNG

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: