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Protein Overview: IMPA1

General Information:
Name(s) found: IMPA1 [HGNC (HUGO)]
Description(s) found:
Found 70 descriptions.
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  • inositol(myo)-1(or 4)-monophosphatase 1 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 277 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADPWQECMD YAVTLARQAG EVVCEAIKNE MNVMLKSSPV DLVTATDQKV EKMLISSIKE  60
   61 KYPSHSFIGE ESVAAGEKSI LTDNPTWIID PIDGTTNFVH RFPFVAVSIG FAVNKKIEFG 120
  121 VVYSCVEGKM YTARKGKGAF CNGQKLQVSQ QEDITKSLLV TELGSSRTPE TVRMVLSNME 180
  181 KLFCIPVHGI RSVGTAAVNM CLVATGGADA YYEMGIHCWD VAGAGIIVTE AGGVLMDVTG 240
  241 GPFDLMSRRV IAANNRILAE RIAKEIQVIP LQRDDED

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..277] PSI-BLAST 84.69897 Inositol monophosphatase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphatase activity
    		•  6.94859134959555 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.73672244222293 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.8594723090245 bayes_pls_golite062009
  • hydrolase activity
    		•  4.43275987578288 bayes_pls_golite062009
  • inositol or phosphatidylinositol phosphatase activity
    		•  3.57479316466542 bayes_pls_golite062009
  • inositol-1(or 4)-monophosphatase activity
    		•  3.34662957972704 bayes_pls_golite062009
  • carbohydrate phosphatase activity
    		•  2.20066245856029 bayes_pls_golite062009
  • catalytic activity
    		•  2.13229228332707 bayes_pls_golite062009
  • fructose 1,6-bisphosphate 1-phosphatase activity
    		•  1.61382250100271 bayes_pls_golite062009
  • 3'(2'),5'-bisphosphate nucleotidase activity
    		•  1.03636246295147 bayes_pls_golite062009
  • binding
    		•  0.890627780120238 bayes_pls_golite062009
  • protein binding
    		•  0.286223098418614 bayes_pls_golite062009
  • nucleotidase activity
    		•  0.191173184964385 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.58

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle