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Protein Overview: SIL1

General Information:
Name(s) found: SIL1 [HGNC (HUGO)]
Description(s) found:
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  • gi|83641896|ref|NP_001032722.1| SIL1 protein precursor [Homo sapiens] [NCBI NR]
  • gi|74733533|sp|Q9H173.1|SIL1_HUMAN RecName: Full=Nucleotide exchange factor SIL1; AltName: Full=BiP-associated protein; Short=BAP; Flags: Precursor [NCBI NR]
  • gi|37183018|gb|AAQ89309.1| SIL1 [Homo sapiens] [NCBI NR]
  • gi|26225130|gb|AAN84477.1| BiP-associated protein precursor; BAP precursor [Homo sapiens] [NCBI NR]
  • gi|22761097|dbj|BAC11452.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|15079466|gb|AAH11568.1| SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae) [Homo sapiens] [NCBI NR]
  • gi|11968009|ref|NP_071909.1| SIL1 protein precursor [Homo sapiens] [NCBI NR]
  • gi|119582525|gb|EAW62121.1| SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae), isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119582524|gb|EAW62120.1| SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae), isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|11558402|emb|CAC17773.1| SIL1 protein [Homo sapiens] [NCBI NR]
  • SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae) [HGNC (HUGO)]
  • Nucleotide exchange factor SIL1 OS=Homo sapiens GN=SIL1 PE=1 SV=1 [Swiss-Prot]
  • SIL1 protein precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • endoplasmic reticulum chaperone SIL1, homolog of yeast; BiP-associated protein [HMR_022704.fasta]
  • SIL1 [Homo sapiens]gi|11968009|ref|NP_071909.1| endoplasmic reticulum chaperone SIL1, homolog of yeast [Homo sapiens]gi|15079466|gb|AAH11568.1| Endoplasmic reticulum chaperone SIL1, homolog of yeast [Homo sapiens]gi|11558402|emb|CAC17773.1| SIL1 protei [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 Nucleotide exchange factor SIL1 precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_022464) endoplasmic reticulum chaperone SIL1, homolog of yeast [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • SIL1 protein precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • endoplasmic reticulum chaperone SIL1, homolog of yeast; BiP-associated protein [Homo sapiens] [HumanGallus06162005.fasta]
  • Nucleotide exchange factor SIL1 precursor (BiP-associated protein) (BAP) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae), isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • SIL1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • BiP-associated protein precursor; BAP precursor [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • SIL1 protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=SIL1 Nucleotide exchange factor SIL1 [human-ipi-250309-contam.fasta]
  • IPI:IPI00296197.2|SWISS-PROT:Q9H173|ENSEMBL:ENSP00000265195;ENSP00000378294|REFSEQ:NP_001032722;NP_071909|H-INV:HIT000296322|VEGA:OTTHUMP00000159527 Tax_Id=9606 Gene_Symbol=SIL1 Nucleotide exchange factor SIL1 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=SIL1 Nucleotide exchange factor SIL1 precursor ENSG00000120725 IPI00296197 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=SIL1 Nucleotide exchange factor SIL1 precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • nucleotide exchange factor SIL1 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q9H173;Q8N2L3; RecName: Full=Nucleotide exchange factor SIL1; AltName: Full=BiP-associated protein; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Nucleotide exchange factor SIL1 OS=Homo sapiens GN=SIL1 [011711_HMR.fasta]
  • IPI:IPI00296197.2|SWISS-PROT:Q9H173|TREMBL:D3DQC2|ENSEMBL:ENSP00000265195;ENSP00000378294|REFSEQ:NP_001032722;NP_071909|H-INV:HIT000296322|VEGA:OTTHUMP00000159527 Tax_Id=9606 Gene_Symbol=SIL1 Nucleotide exchange factor SIL1 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=SIL1 Synonyms=BAP|MSS|ULG5 nucleotide exchange factor SIL1 precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00296197.2|SWISS-PROT:Q9H173|ENSEMBL:ENSP00000265195;ENSP00000378294|REFSEQ:NP_001032722;NP_071909|H-INV:HIT000296322|VEGA:OTTHUMP00000159527;OTTHUMP00000223767 Tax_Id=9606 Gene_Symbol=SIL1 Nucleotide exchange factor SIL1 [ipi.HUMAN.20110912.fasta]
  • Nucleotide exchange factor SIL1 GN=SIL1 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 461 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPQSLPSSR MAPLGMLLGL LMAACFTFCL SHQNLKEFAL TNPEKSSTKE TERKETKAEE  60
   61 ELDAEVLEVF HPTHEWQALQ PGQAVPAGSH VRLNLQTGER EAKLQYEDKF RNNLKGKRLD 120
  121 INTNTYTSQD LKSALAKFKE GAEMESSKED KARQAEVKRL FRPIEELKKD FDELNVVIET 180
  181 DMQIMVRLIN KFNSSSSSLE EKIAALFDLE YYVHQMDNAQ DLLSFGGLQV VINGLNSTEP 240
  241 LVKEYAAFVL GAAFSSNPKV QVEAIEGGAL QKLLVILATE QPLTAKKKVL FALCSLLRHF 300
  301 PYAQRQFLKL GGLQVLRTLV QEKGTEVLAV RVVTLLYDLV TEKMFAEEEA ELTQEMSPEK 360
  361 LQQYRQVHLL PGLWEQGWCE ITAHLLALPE HDAREKVLQT LGVLLTTCRD RYRQDPQLGR 420
  421 TLASLQAEYQ VLASLELQDG EDEGYFQELL GSVNSLLKEL R

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..461] PSI-BLAST 62.0 Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.04462323043166 bayes_pls_golite062009
  • protein binding
    		•  1.04044934052933 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.549076739943715 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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