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Protein Overview: gi|18497288, gi|...

General Information:
Name(s) found: gi|18497288 [NCBI NR]
gi|18466810 [NCBI NR]
Description(s) found:
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  • gi|18497288|ref|NP_066548.2| latent transforming growth factor beta binding protein 3 isoform 2 [Homo sapiens] [NCBI NR]
  • gi|18466810|gb|AAF62352.3|AF135960_1 latent transforming growth factor beta binding protein 3 [Homo sapiens] [NCBI NR]
  • Latent transforming growth factor beta binding protein 3 [hmr_yeast5_DM3-1_pombe.fasta]
  • latent transforming growth factor beta binding protein 3 [HMR_022704.fasta]
  • latent transforming growth factor beta binding protein 3 [Homo sapiens]gi|18466810|gb|AAF62352.3| latent transforming growth factor beta binding protein 3 [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 latent transforming growth factor beta binding protein 3 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_021070) latent transforming growth factor beta binding protein 3 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • latent transforming growth factor beta binding protein 3 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Latent transforming growth factor beta binding protein 3 [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • Tax_Id=9606 Latent transforming growth factor beta binding protein 3 [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • latent transforming growth factor beta binding protein 3 isoform 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 2 of Latent-transforming growth factor beta-binding protein 3 precursor [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 LATENT TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN 3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=LTBP3 Isoform 2 of Latent-transforming growth factor beta-binding protein 3 [human-ipi-250309-contam.fasta]
  • latent transforming growth factor beta binding protein 3 isoform 2 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_02-15-2010_reversed.fasta]
  • IPI:IPI00398794.2|SWISS-PROT:Q9NS15-2|TREMBL:B4DQL8;B9EG76|ENSEMBL:ENSP00000326647|REFSEQ:NP_066548|H-INV:HIT000071068 Tax_Id=9606 Gene_Symbol=LTBP3 Isoform 2 of Latent-transforming growth factor beta-binding protein 3 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=LTBP3 Isoform 2 of Latent-transforming growth factor beta-binding protein 3 precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • latent-transforming growth factor beta-binding protein 3 isoform 2 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Isoform 2 of Latent-transforming growth factor beta-binding protein 3 OS=Homo sapiens GN=LTBP3 [011711_HMR.fasta]
  • IPI:IPI00398794.2|SWISS-PROT:Q9NS15-2|ENSEMBL:ENSP00000326647|REFSEQ:NP_066548|H-INV:HIT000071068 Tax_Id=9606 Gene_Symbol=LTBP3 Isoform 2 of Latent-transforming growth factor beta-binding protein 3 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=LTBP3 Synonyms=DKFZp586M2123|FLJ33431|FLJ39893|FLJ42533|FLJ44138|FLJ45576|LTBP-3|LTBP2|STHAG6|pp6425 latent-transforming growth factor beta-binding protein 3 isoform 2 precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00398794.2|SWISS-PROT:Q9NS15-2|ENSEMBL:ENSP00000326647|REFSEQ:NP_066548|H-INV:HIT000071068|VEGA:OTTHUMP00000233545 Tax_Id=9606 Gene_Symbol=LTBP3 Isoform 2 of Latent-transforming growth factor beta-binding protein 3 [ipi.HUMAN.20110912.fasta]
  • Isoform 2 of Latent-transforming growth factor beta-binding protein 3 GN=LTBP3 [Doctor+uniprot-HUMAN-120911.fasta]
  • Isoform of Q9NS15, Isoform 2 of Latent-transforming growth factor beta-binding protein 3 OS=Homo sapiens GN=LTBP3 [2016-04-human-contam-aPKC-His-Par6.fasta]
    • Organism: Homo sapiens
    Length: 1256 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGPRGAAGG LAPEMRGAGA AGLLALLLLL LLLLLGLGGR VEGGPAGERG AGGGGALARE  60
   61 RFKVVFAPVI CKRTCLKGQC RDSCQQGSNM TLIGENGHST DTLTGSGFRV VVCPLPCMNG 120
  121 GQCSSRNQCL CPPDFTGRFC QVPAGGAGGG TGGSGPGLSR TGALSTGALP PLAPEGDSVA 180
  181 SKHAIYAVQV IADPPGPGEG PPAQHAAFLV PLGPGQISAE VQAPPPVVNV RVHHPPEASV 240
  241 QVHRIESSNA ESAAPSQHLL PHPKPSHPRP PTQKPLGRCF QDTLPKQPCG SNPLPGLTKQ 300
  301 EDCCGSIGTA WGQSKCHKCP QLQYTGVQKP GPVRGEVGAD CPQGYKRLNS THCQDINECA 360
  361 MPGVCRHGDC LNNPGSYRCV CPPGHSLGPS RTQCIADKPE EKSLCFRLVS PEHQCQHPLT 420
  421 TRLTRQLCCC SVGKAWGARC QRCPTDGTAA FKEICPAGKG YHILTSHQTL TIQGESDFSL 480
  481 FLHPDGPPKP QQLPESPSQA PPPEDTEEER GVTTDSPVSE ERSVQQSHPT ATTTPARPYP 540
  541 ELISRPSPPT MRWFLPDLPP SRSAVEIAPT QVTETDECRL NQNICGHGEC VPGPPDYSCH 600
  601 CNPGYRSHPQ HRYCVDVNEC EAEPCGPGRG ICMNTGGSYN CHCNRGYRLH VGAGGRSCVD 660
  661 LNECAKPHLC GDGGFCINFP GHYKCNCYPG YRLKASRPPV CEDIDECRDP SSCPDGKCEN 720
  721 KPGSFKCIAC QPGYRSQGGG ACRDVNECAE GSPCSPGWCE NLPGSFRCTC AQGYAPAPDG 780
  781 RSCLDVDECE AGDVCDNGIC SNTPGSFQCQ CLSGYHLSRD RSHCEDIDEC DFPAACIGGD 840
  841 CINTNGSYRC LCPQGHRLVG GRKCQDIDEC SQDPSLCLPH GACKNLQGSY VCVCDEGFTP 900
  901 TQDQHGCEEV EQPHHKKECY LNFDDTVFCD SVLATNVTQQ ECCCSLGAGW GDHCEIYPCP 960
  961 VYSSAEFHSL CPDGKGYTQD NNIVNYGIPA HRDIDECMLF GSEICKEGKC VNTQPGYECY1020
 1021 CKQGFYYDGN LLECVDVDEC LDESNCRNGV CENTRGGYRC ACTPPAEYSP AQRQCLSPEE1080
 1081 MERAPERRDV CWSQRGEDGM CAGPLAGPAL TFDDCCCRQG RGWGAQCRPC PPRGAGSHCP1140
 1141 TSQSESNSFW DTSPLLLGKP PRDEDSSEED SDECRCVSGR CVPRPGGAVC ECPGGFQLDA1200
 1201 SRARCVDIDE CRELNQRGLL CKSERCVNTS GSFRCVCKAG FARSRPHGAC VPQRRR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..211] PSI-BLAST 4.39794 No description for 2gy5A was found.
    2 View Details [212..311] deduced N/A No confident structure predictions are available.
    3 View Details [312..361] FFAS03 2.39 Coagulation factor VIIa
    4 View Details [362..613] FFAS03 4.11 Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, holo form.
    5 View Details [614..698] PSI-BLAST 5.0 Fibrillin-1
    6 View Details [699..784] FFAS03 2.78 Activated protein c (autoprothrombin IIa)
    7 View Details [785..867] PSI-BLAST 3.69897 NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, MINIMIZED AVERAGE STRUCTURE
    8 View Details [868..1256] PSI-BLAST 16.69897 Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  1.36707749198024 bayes_pls_golite062009
  • structural constituent of bone
    		•  1.09446266124376 bayes_pls_golite062009
  • protein binding
    		•  0.193079522686232 bayes_pls_golite062009
    4 No functions predicted.
    5
    Term Confidence Notes
  • receptor binding
    		•  4.60755835611133 bayes_pls_golite062009
  • growth factor activity
    		•  4.38305031783896 bayes_pls_golite062009
  • epidermal growth factor receptor binding
    		•  2.63546895705146 bayes_pls_golite062009
  • extracellular matrix structural constituent
    		•  2.25506386782176 bayes_pls_golite062009
  • binding
    		•  2.07793256968292 bayes_pls_golite062009
  • protein binding
    		•  1.71989387545809 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  1.59362625477231 bayes_pls_golite062009
  • heparin binding
    		•  1.18377533277052 bayes_pls_golite062009
  • polysaccharide binding
    		•  0.9177636847106 bayes_pls_golite062009
  • ErbB-3 class receptor binding
    		•  0.65339109098708 bayes_pls_golite062009
  • pattern binding
    		•  0.59201056851242 bayes_pls_golite062009
  • ErbB-2 class receptor binding
    		•  0.470263535896705 bayes_pls_golite062009
    6
    Term Confidence Notes
  • receptor binding
    		•  4.27252497280864 bayes_pls_golite062009
  • growth factor activity
    		•  3.99323701198118 bayes_pls_golite062009
  • extracellular matrix structural constituent
    		•  2.12504268450415 bayes_pls_golite062009
  • epidermal growth factor receptor binding
    		•  2.11629206230008 bayes_pls_golite062009
  • binding
    		•  1.98073403587238 bayes_pls_golite062009
  • protein binding
    		•  1.57046350131335 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  1.34029908248821 bayes_pls_golite062009
  • heparin binding
    		•  0.904794195857948 bayes_pls_golite062009
  • polysaccharide binding
    		•  0.683674808850842 bayes_pls_golite062009
  • pattern binding
    		•  0.377980933320322 bayes_pls_golite062009
  • ErbB-3 class receptor binding
    		•  0.0837042404322571 bayes_pls_golite062009
    7 No functions predicted.
    8
    Term Confidence Notes
  • receptor binding
    		•  4.60755835611133 bayes_pls_golite062009
  • growth factor activity
    		•  4.38305031783896 bayes_pls_golite062009
  • epidermal growth factor receptor binding
    		•  2.63546895705146 bayes_pls_golite062009
  • extracellular matrix structural constituent
    		•  2.25506386782176 bayes_pls_golite062009
  • binding
    		•  2.07793256968292 bayes_pls_golite062009
  • protein binding
    		•  1.71989387545809 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  1.59362625477231 bayes_pls_golite062009
  • heparin binding
    		•  1.18377533277052 bayes_pls_golite062009
  • polysaccharide binding
    		•  0.9177636847106 bayes_pls_golite062009
  • ErbB-3 class receptor binding
    		•  0.65339109098708 bayes_pls_golite062009
  • pattern binding
    		•  0.59201056851242 bayes_pls_golite062009
  • ErbB-2 class receptor binding
    		•  0.470263535896705 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle