Protein Overview: TDO2

General Information:
Name(s) found:	TDO2 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|993046\|gb\|AAB08514.1\| tryptophan oxygenase [Homo sapiens] [NCBI NR] pir\|\|G02022 tryptophan oxygenase - human [NCBI NR] gi\|5032165\|ref\|NP_005642.1\| tryptophan 2,3-dioxygenase [Homo sapiens] [NCBI NR] gi\|158259859\|dbj\|BAF82107.1\| unnamed protein product [Homo sapiens] [NCBI NR] gi\|13529173\|gb\|AAH05355.1\| Tryptophan 2,3-dioxygenase [Homo sapiens] [NCBI NR] gi\|1351188\|sp\|P48775.1\|T23O_HUMAN RecName: Full=Tryptophan 2,3-dioxygenase; Short=TDO; AltName: Full=Tryptophan pyrrolase; Short=Tryptophanase; AltName: Full=Tryptophan oxygenase; Short=TRPO; Short=TO; AltName: Full=Tryptamin 2,3-dioxygenase [NCBI NR] gi\|119625290\|gb\|EAX04885.1\| tryptophan 2,3-dioxygenase, isoform CRA_b [Homo sapiens] [NCBI NR] tryptophan 2,3-dioxygenase [HGNC (HUGO)] Tryptophan 2,3-dioxygenase OS=Homo sapiens GN=TDO2 PE=1 SV=1 [Swiss-Prot] Tryptophan 2,3-dioxygenase [hmr_yeast5_DM3-1_pombe.fasta] tryptophan 2,3-dioxygenase; Tryptophan oxygenase [HMR_022704.fasta] tryptophan 2,3-dioxygenase [Homo sapiens]gi\|13529173\|gb\|AAH05355.1\| Tryptophan 2,3-dioxygenase [Homo sapiens]gi\|1351188\|sp\|P48775\|T23O_HUMAN Tryptophan 2,3-dioxygenase (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygen [nrdb_11152004_Chlamydomonas] Tryptophan 2,3-dioxygenase (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Tryptophan 2,3-dioxygenase [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_005651) tryptophan 2,3-dioxygenase; Tryptophan oxygenase [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] tryptophan 2,3-dioxygenase [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] tryptophan 2,3-dioxygenase; Tryptophan oxygenase [Homo sapiens] [HumanGallus06162005.fasta] Tryptophan 2,3-dioxygenase (TO) (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] tryptophan 2,3-dioxygenase, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tryptophan 2,3-dioxygenase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] tryptophan oxygenase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 TRYPTOPHAN 2,3-DIOXYGENASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=TDO2 Tryptophan 2,3-dioxygenase [human-ipi-250309-contam.fasta] IPI:IPI00011206.3\|SWISS-PROT:P48775\|TREMBL:A8K053\|ENSEMBL:ENSP00000281525\|REFSEQ:NP_005642\|H-INV:HIT000219299 Tax_Id=9606 Gene_Symbol=TDO2 Tryptophan 2,3-dioxygenase [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=TDO2 Tryptophan 2,3-dioxygenase ENSG00000151790 IPI00011206 [drosphohumanreversed.fasta] P48775;A8K053; RecName: Full=Tryptophan 2,3-dioxygenase; AltName: Full=Tryptophan pyrrolase; AltName: Full=Tryptophanase; AltName: Full=Tryptophan oxygenase; AltName: Full=Tryptamin 2,3-dioxygenase; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Tryptophan 2,3-dioxygenase OS=Homo sapiens GN=TDO2 [011711_HMR.fasta] IPI:IPI00011206.3\|SWISS-PROT:P48775\|ENSEMBL:ENSP00000281525\|REFSEQ:NP_005642\|H-INV:HIT000219299 Tax_Id=9606 Gene_Symbol=TDO2 Tryptophan 2,3-dioxygenase [ipi.HUMAN.fasta.20100406] GeneSymbol=TDO2 Synonyms=TDO\|TPH2\|TRPO tryptophan 2,3-dioxygenase [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00011206.3\|SWISS-PROT:P48775\|ENSEMBL:ENSP00000281525;ENSP00000444788\|REFSEQ:NP_005642\|H-INV:HIT000219299\|VEGA:OTTHUMP00000220788 Tax_Id=9606 Gene_Symbol=TDO2 Tryptophan 2,3-dioxygenase [ipi.HUMAN.20110912.fasta] Tryptophan 2,3-dioxygenase GN=TDO2 [Doctor+uniprot-HUMAN-120911.fasta] IPI:IPI00011206.3\|SWISS-PROT:P48775\|ENSEMBL:ENSP00000444788\|REFSEQ:NP_005642\|H-INV:HIT000219299\|VEGA:OTTHUMP00000220788 Tax_Id=9606 Gene_Symbol=TDO2 Tryptophan 2,3-dioxygenase [ipi.HUMAN.fasta.20110927] Tryptophan 2,3-dioxygenase OS=Homo sapiens GN=TDO2 PE=2 SV=1 [HUMAN.fasta.20131015]
Organism:	Homo sapiens
Length:	406 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGCPFLGNN FGYTFKKLPV EGSEEDKSQT GVNRASKGGL IYGNYLHLEK VLNAQELQSE  60
   61 TKGNKIHDEH LFIITHQAYE LWFKQILWEL DSVREIFQNG HVRDERNMLK VVSRMHRVSV 120
  121 ILKLLVQQFS ILETMTALDF NDFREYLSPA SGFQSLQFRL LENKIGVLQN MRVPYNRRHY 180
  181 RDNFKGEENE LLLKSEQEKT LLELVEAWLE RTPGLEPHGF NFWGKLEKNI TRGLEEEFIR 240
  241 IQAKEESEEK EEQVAEFQKQ KEVLLSLFDE KRHEHLLSKG ERRLSYRALQ GALMIYFYRE 300
  301 EPRFQVPFQL LTSLMDIDSL MTKWRYNHVC MVHRMLGSKA GTGGSSGYHY LRSTVSDRYK 360
  361 VFVDLFNLST YLIPRHWIPK MNPTIHKFLY TAEYCDSSYF SSDESD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: TDO2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: