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Protein Overview: PEX12

General Information:
Name(s) found: PEX12 [HGNC (HUGO)]
Description(s) found:
Found 35 descriptions.
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  • peroxisomal biogenesis factor 12 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 359 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEHGAHFTA ASVADDQPSI FEVVAQDSLM TAVRPALQHV VKVLAESNPT HYGFLWRWFD  60
   61 EIFTLLDLLL QQHYLSRTSA SFSENFYGLK RIVMGDTHKS QRLASAGLPK QQLWKSIMFL 120
  121 VLLPYLKVKL EKLVSSLREE DEYSIHPPSS RWKRFYRAFL AAYPFVNMAW EGWFLVQQLR 180
  181 YILGKAQHHS PLLRLAGVQL GRLTVQDIQA LEHKPAKASM MQQPARSVSE KINSALKKAV 240
  241 GGVALSLSTG LSVGVFFLQF LDWWYSSENQ ETIKSLTALP TPPPPVHLDY NSDSPLLPKM 300
  301 KTVCPLCRKT RVNDTVLATS GYVFCYRCVF HYVRSHQACP ITGYPTEVQH LIKLYSPEN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..138] Pfam 18.481486 No description for PF04757.5 was found. Confident ab initio structure predictions are available.
    2 View Details [139..359] PSI-BLAST 12.154902 Cbl; N-terminal domain of cbl (N-cbl); CBL

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • signal transducer activity
    		•  2.59589726924784 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.59589726924784 bayes_pls_golite062009
  • binding
    		•  2.49943137715788 bayes_pls_golite062009
  • protein binding
    		•  2.04603930248857 bayes_pls_golite062009
  • transporter activity
    		•  1.15928534291452 bayes_pls_golite062009
  • calcium ion binding
    		•  1.03474411638676 bayes_pls_golite062009
  • molecular adaptor activity
    		•  1.01125482062944 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.945691505472547 bayes_pls_golite062009
  • SH3/SH2 adaptor activity
    		•  0.80276046490236 bayes_pls_golite062009
  • receptor binding
    		•  0.79540672491346 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.75057755360417 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.693724160233023 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.45412801027969 bayes_pls_golite062009
  • protein binding, bridging
    		•  0.28270375006511 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.246383459363256 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.193201281459889 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0305250212662123 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle