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Protein Overview: HGS

General Information:
Name(s) found: HGS [HGNC (HUGO)]
Description(s) found:
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  • gi|71152119|sp|O14964.1|HGS_HUMAN RecName: Full=Hepatocyte growth factor-regulated tyrosine kinase substrate; AltName: Full=Protein pp110; AltName: Full=Hrs [NCBI NR]
  • gi|4758528|ref|NP_004703.1| hepatocyte growth factor-regulated tyrosine kinase substrate [Homo sapiens] [NCBI NR]
  • gi|32879851|gb|AAP88756.1| hepatocyte growth factor-regulated tyrosine kinase substrate [Homo sapiens] [NCBI NR]
  • gi|2731383|gb|AAC51929.1| hepatocyte growth factor-regulated tyrosine kinase substrate [Homo sapiens] [NCBI NR]
  • gi|2618588|dbj|BAA23366.1| Hrs [Homo sapiens] [NCBI NR]
  • gi|13097723|gb|AAH03565.1| Hepatocyte growth factor-regulated tyrosine kinase substrate [Homo sapiens] [NCBI NR]
  • gi|119610081|gb|EAW89675.1| hepatocyte growth factor-regulated tyrosine kinase substrate, isoform CRA_a [Homo sapiens] [NCBI NR]
  • hepatocyte growth factor-regulated tyrosine kinase substrate [HGNC (HUGO)]
  • Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Homo sapiens GN=HGS PE=1 SV=1 [Swiss-Prot]
  • HRS protein [hmr_yeast5_DM3-1_pombe.fasta]
  • hepatocyte growth factor-regulated tyrosine kinase substrate; human growth factor-regulated tyrosine kinase substrate [HMR_022704.fasta]
  • hepatocyte growth factor-regulated tyrosine kinase substrate [Homo sapiens]gi|32879851|gb|AAP88756.1| hepatocyte growth factor-regulated tyrosine kinase substrate [Homo sapiens]gi|13097723|gb|AAH03565.1| Hepatocyte growth factor-regulated tyrosine kinas [nrdb_11152004_Chlamydomonas]
  • Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Hepatocyte growth factor-regulated tyrosine kinase substrate [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_004712) hepatocyte growth factor-regulated tyrosine kinase substrate; human growth factor-regulated tyrosine kinase substrate [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • hepatocyte growth factor-regulated tyrosine kinase substrate [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Hrs [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • hepatocyte growth factor-regulated tyrosine kinase substrate; human growth factor-regulated tyrosine kinase substrate [Homo sapiens] [HumanGallus06162005.fasta]
  • hepatocyte growth factor-regulated tyrosine kinase substrate, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Hepatocyte growth factor-regulated tyrosine kinase substrate [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Hrs [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • RecName: Full=Hepatocyte growth factor-regulated tyrosine kinase substrate; AltName: Full=Protein pp110; AltName: Full=Hrs [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=HGS Isoform 1 of Hepatocyte growth factor-regulated tyrosine kinase substrate [human-ipi-250309-contam.fasta]
  • IPI:IPI00006176.3|SWISS-PROT:O14964-1|ENSEMBL:ENSP00000331201|REFSEQ:NP_004703|H-INV:HIT000031603|VEGA:OTTHUMP00000181430 Tax_Id=9606 Gene_Symbol=HGS Isoform 1 of Hepatocyte growth factor-regulated tyrosine kinase substrate [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=HGS Hepatocyte growth factor-regulated tyrosine kinase substrate ENSG00000185359 IPI00006176 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=HGS Hepatocyte growth factor-regulated tyrosine kinase substrate [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • O14964;Q9NR36; RecName: Full=Hepatocyte growth factor-regulated tyrosine kinase substrate; AltName: Full=Protein pp110; AltName: Full=Hrs; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Homo sapiens GN=HGS [011711_HMR.fasta]
  • GeneSymbol=HGS Synonyms=FLJ11421|FLJ39878|HRS hepatocyte growth factor-regulated tyrosine kinase substrate [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00006176.3|SWISS-PROT:O14964-1|ENSEMBL:ENSP00000331201|REFSEQ:NP_004703|H-INV:HIT000031603 Tax_Id=9606 Gene_Symbol=HGS Isoform 1 of Hepatocyte growth factor-regulated tyrosine kinase substrate [ipi.HUMAN.20110912.fasta]
  • Hepatocyte growth factor-regulated tyrosine kinase substrate GN=HGS [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 777 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRGSGTFER LLDKATSQLL LETDWESILQ ICDLIRQGDT QAKYAVNSIK KKVNDKNPHV  60
   61 ALYALEVMES VVKNCGQTVH DEVANKQTME ELKDLLKRQV EVNVRNKILY LIQAWAHAFR 120
  121 NEPKYKVVQD TYQIMKVEGH VFPEFKESDA MFAAERAPDW VDAEECHRCR VQFGVMTRKH 180
  181 HCRACGQIFC GKCSSKYSTI PKFGIEKEVR VCEPCYEQLN RKAEGKATST TELPPEYLTS 240
  241 PLSQQSQLPP KRDETALQEE EELQLALALS QSEAEEKERL RQKSTYTSYP KAEPMPSASS 300
  301 APPASSLYSS PVNSSAPLAE DIDPELARYL NRNYWEKKQE EARKSPTPSA PVPLTEPAAQ 360
  361 PGEGHAAPTN VVENPLPETD SQPIPPSGGP FSEPQFHNGE SEESHEQFLK ALQNAVTTFV 420
  421 NRMKSNHMRG RSITNDSAVL SLFQSINGMH PQLLELLNQL DERRLYYEGL QDKLAQIRDA 480
  481 RGALSALREE HREKLRRAAE EAERQRQIQL AQKLEIMRQK KQEYLEVQRQ LAIQRLQEQE 540
  541 KERQMRLEQQ KQTVQMRAQM PAFPLPYAQL QAMPAAGGVL YQPSGPASFP STFSPAGSVE 600
  601 GSPMHGVYMS QPAPAAGPYP SMPSTAADPS MVSAYMYPAG ATGAQAAPQA QAGPTASPAY 660
  661 SSYQPTPTAG YQNVASQAPQ SLPAISQPPQ SSTMGYMGSQ SVSMGYQPYN MQNLMTTLPS 720
  721 QDASLPPQQP YIAGQQPMYQ QMAPSGGPPQ QQPPVAQQPQ AQGPPAQGSE AQLISFD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle