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Protein Overview: SRD5A1

General Information:
Name(s) found: SRD5A1 [HGNC (HUGO)]
Description(s) found:
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  • gi|4507201|ref|NP_001038.1| steroid-5-alpha-reductase 1 [Homo sapiens] [NCBI NR]
  • gi|338476|gb|AAA60995.1| steroid 5-alpha-reductase [Homo sapiens] [NCBI NR]
  • gi|3360435|gb|AAC28620.1| steroid 5-alpha-reductase [Homo sapiens] [NCBI NR]
  • gi|32891811|gb|AAP88935.1| steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) [Homo sapiens] [NCBI NR]
  • gi|30582507|gb|AAP35480.1| steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) [Homo sapiens] [NCBI NR]
  • gi|189053646|dbj|BAG35898.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|177767|gb|AAA35490.1| steroid 5-alpha-reductase (EC 1.3.99.5) [NCBI NR]
  • gi|14250468|gb|AAH08673.1| Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) [Homo sapiens] [NCBI NR]
  • gi|13937855|gb|AAH07033.1| Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) [Homo sapiens] [NCBI NR]
  • gi|134151|sp|P18405.1|S5A1_HUMAN RecName: Full=3-oxo-5-alpha-steroid 4-dehydrogenase 1; AltName: Full=Steroid 5-alpha-reductase 1; Short=S5AR; AltName: Full=SR type 1 [NCBI NR]
  • gi|119628509|gb|EAX08104.1| steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1), isoform CRA_b [Homo sapiens] [NCBI NR]
  • pir||A55274 3-oxo-5alpha-steroid 4-dehydrogenase (EC 1.3.99.5) - human [NCBI NR]
  • steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) [HGNC (HUGO)]
  • 3-oxo-5-alpha-steroid 4-dehydrogenase 1 OS=Homo sapiens GN=SRD5A1 PE=1 SV=1 [Swiss-Prot]
  • 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [hmr_yeast5_DM3-1_pombe.fasta]
  • steroid-5-alpha-reductase 1; 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1; 5-alpha reductase [HMR_022704.fasta]
  • steroid-5-alpha-reductase 1 [Homo sapiens]gi|32891811|gb|AAP88935.1| steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) [Homo sapiens]gi|30582507|gb|AAP35480.1| steroid-5-alpha-reductase, alpha polypepti [nrdb_11152004_Chlamydomonas]
  • 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Steroid 5-alpha-reductase 1) (SR type 1) (S5AR) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_001047) steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1); 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1; 5-alpha reductase [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • steroid-5-alpha-reductase 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • steroid-5-alpha-reductase 1; 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1; 5-alpha reductase [Homo sapiens] [HumanGallus06162005.fasta]
  • 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Steroid 5-alpha-reductase 1) (S5AR) (SR type 1) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1), isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • steroid 5-alpha-reductase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • steroid 5-alpha-reductase [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • steroid 5-alpha-reductase (EC 1.3.99.5) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [human-ipi-250309-contam.fasta]
  • IPI:IPI00032233.1|SWISS-PROT:P18405|TREMBL:B2R7Q1|ENSEMBL:ENSP00000274192|REFSEQ:NP_001038|H-INV:HIT000064321|VEGA:OTTHUMP00000115519 Tax_Id=9606 Gene_Symbol=SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 ENSG00000145545 IPI00032233 [drosphohumanreversed.fasta]
  • P18405;B2R7Q1;Q9UHY4;Q9UP36;Q9UP37; RecName: Full=3-oxo-5-alpha-steroid 4-dehydrogenase 1; AltName: Full=Steroid 5-alpha-reductase 1; AltName: Full=SR type 1; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • 3-oxo-5-alpha-steroid 4-dehydrogenase 1 OS=Homo sapiens GN=SRD5A1 [011711_HMR.fasta]
  • IPI:IPI00032233.1|SWISS-PROT:P18405|ENSEMBL:ENSP00000274192|REFSEQ:NP_001038|H-INV:HIT000064321|VEGA:OTTHUMP00000115519 Tax_Id=9606 Gene_Symbol=SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=SRD5A1 Synonyms=S5AR 1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • 3-oxo-5-alpha-steroid 4-dehydrogenase 1 GN=SRD5A1 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 259 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATATGVAEE RLLAALAYLQ CAVGCAVFAR NRQTNSVYGR HALPSHRLRV PARAAWVVQE  60
   61 LPSLALPLYQ YASESAPRLR SAPNCILLAM FLVHYGHRCL IYPFLMRGGK PMPLLACTMA 120
  121 IMFCTCNGYL QSRYLSHCAV YADDWVTDPR FLIGFGLWLT GMLINIHSDH ILRNLRKPGD 180
  181 TGYKIPRGGL FEYVTAANYF GEIMEWCGYA LASWSVQGAA FAFFTFCFLS GRAKEHHEWY 240
  241 LRKFEEYPKF RKIIIPFLF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..107] MSA 5.196997 View MSA. No confident structure predictions are available.
    2 View Details [108..259] Pfam 104.744727 No description for PF02544.7 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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