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Protein Overview: FGF13

General Information:
Name(s) found: FGF13 [HGNC (HUGO)]
Description(s) found:
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  • gi|66350813|emb|CAI95673.1| fibroblast growth factor 13 [Homo sapiens] [NCBI NR]
  • gi|66347225|emb|CAI95613.1| fibroblast growth factor 13 [Homo sapiens] [NCBI NR]
  • gi|50234979|gb|AAT70720.1| fibroblast growth factor 13 [Homo sapiens] [NCBI NR]
  • gi|4758366|ref|NP_004105.1| fibroblast growth factor 13 isoform 1 [Homo sapiens] [NCBI NR]
  • gi|4323513|gb|AAD16400.1| fibroblast growth factor 13 isoform 1A [Homo sapiens] [NCBI NR]
  • gi|2494461|sp|Q92913.1|FGF13_HUMAN RecName: Full=Fibroblast growth factor 13; Short=FGF-13; AltName: Full=Fibroblast growth factor homologous factor 2; Short=FHF-2 [NCBI NR]
  • gi|21706385|gb|AAH34340.1| Fibroblast growth factor 13 [Homo sapiens] [NCBI NR]
  • gi|158260943|dbj|BAF82649.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|15706434|gb|AAH12347.1| Fibroblast growth factor 13 [Homo sapiens] [NCBI NR]
  • gi|1563887|gb|AAB18914.1| fibroblast growth factor homologous factor 2 [Homo sapiens] [NCBI NR]
  • gi|119608843|gb|EAW88437.1| fibroblast growth factor 13, isoform CRA_c [Homo sapiens] [NCBI NR]
  • fibroblast growth factor 13 [HGNC (HUGO)]
  • (Q92913) Fibroblast growth factor-13 (FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2) [Swiss-Prot]
  • Fibroblast growth factor 13 OS=Homo sapiens GN=FGF13 PE=1 SV=1 [Swiss-Prot]
  • Splice isoform 1A of Q92913 [hmr_yeast5_DM3-1_pombe.fasta]
  • fibroblast growth factor 13 isoform 1A; fibroblast growth factor homologous factor 2 [HMR_022704.fasta]
  • fibroblast growth factor 13 isoform 1A [Homo sapiens]gi|50234979|gb|AAT70720.1| fibroblast growth factor 13 [Homo sapiens]gi|21706385|gb|AAH34340.1| Fibroblast growth factor 13, isoform 1A [Homo sapiens]gi|15706434|gb|AAH12347.1| Fibroblast growth fact [nrdb_11152004_Chlamydomonas]
  • Fibroblast growth factor 13 (FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1A of Fibroblast growth factor 13 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • fibroblast growth factor 13, isoform 1A; fibroblast growth factor homologous factor 2 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • fibroblast growth factor 13 isoform 1A [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1A of Fibroblast growth factor-13 [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • fibroblast growth factor 13 isoform 1A; fibroblast growth factor homologous factor 2 [Homo sapiens] [HumanGallus06162005.fasta]
  • fibroblast growth factor 13 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • fibroblast growth factor 13, isoform CRA_c [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Fibroblast growth factor 13 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • fibroblast growth factor homologous factor 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1A of Fibroblast growth factor 13 [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 1 OF FIBROBLAST GROWTH FACTOR-13 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Fibroblast growth factor 13; Short=FGF-13; AltName: Full=Fibroblast growth factor homologous factor 2; Short=FHF-2 [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • fibroblast growth factor 13 isoform 1 [Homo sapiens] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=FGF13 Isoform 1A of Fibroblast growth factor 13 [human-ipi-250309-contam.fasta]
  • IPI:IPI00024251.1|SWISS-PROT:Q92913-1|TREMBL:A8K1P5|ENSEMBL:ENSP00000322390|REFSEQ:NP_004105|VEGA:OTTHUMP00000024143 Tax_Id=9606 Gene_Symbol=FGF13 Isoform 1A of Fibroblast growth factor 13 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Q92913;B1AK18;O95830; RecName: Full=Fibroblast growth factor 13; AltName: Full=Fibroblast growth factor homologous factor 2; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1A of Fibroblast growth factor 13 OS=Homo sapiens GN=FGF13 [011711_HMR.fasta]
  • Fibroblast growth factor 13 OS=Homo sapiens GN=FGF13 [011711_HMR.fasta]
  • Fibroblast growth factor 13 n=17 Tax=Euteleostomi RepID=FGF13_HUMAN [UniProt_Xenopus_laevis_01-01-2011_reversed.fasta]
  • GeneSymbol=FGF13 Synonyms=FGF2|FHF-2|FHF2 fibroblast growth factor 13 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Fibroblast growth factor 13 GN=FGF13 [Doctor+uniprot-HUMAN-120911.fasta]
  • Fibroblast growth factor OS=Homo sapiens GN=FGF13 PE=2 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 245 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAIASSLI RQKRQARERE KSNACKCVSS PSKGKTSCDK NKLNVFSRVK LFGSKKRRRR  60
   61 RPEPQLKGIV TKLYSRQGYH LQLQADGTID GTKDEDSTYT LFNLIPVGLR VVAIQGVQTK 120
  121 LYLAMNSEGY LYTSELFTPE CKFKESVFEN YYVTYSSMIY RQQQSGRGWY LGLNKEGEIM 180
  181 KGNHVKKNKP AAHFLPKPLK VAMYKEPSLH DLTEFSRSGS GTPTKSRSVS GVLNGGKSMS 240
  241 HNEST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..245] PSI-BLAST 50.69897 Crystal structure of human FHF1b (FGF12b)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor binding
    		•  4.30358117760805 bayes_pls_golite062009
  • growth factor activity
    		•  3.97089267530575 bayes_pls_golite062009
  • cytokine activity
    		•  3.76931834545338 bayes_pls_golite062009
  • binding
    		•  2.90110516688922 bayes_pls_golite062009
  • protein binding
    		•  1.94397222237906 bayes_pls_golite062009
  • fibroblast growth factor receptor binding
    		•  1.9437092554389 bayes_pls_golite062009
  • pattern binding
    		•  0.839280621598109 bayes_pls_golite062009
  • interleukin-1 receptor binding
    		•  0.8084616632765 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  0.69866345905635 bayes_pls_golite062009
  • heparin binding
    		•  0.290941670257021 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle